Pharmacologic Treatment Strategies

Author(s):  
Rachael A. Evans ◽  
Robert G. Varadi ◽  
Kambiz Mirzaei ◽  
Roger S. Goldstein
2014 ◽  
Vol 3 (2) ◽  
pp. 595-613 ◽  
Author(s):  
Gayotri Goswami ◽  
Nataliya Shinkazh ◽  
Nichola Davis

2019 ◽  
Vol 06 (02) ◽  
pp. 145-152
Author(s):  
Andrew K. Treister ◽  
Ines P. Koerner

AbstractMeningitis and encephalitis are two inflammatory, often infectious, disorders of the meninges and the central nervous system. Both are associated with significant morbidity and mortality, and require early and aggressive targeted treatment. This article reviews pharmacologic treatment strategies for infectious meningitis and encephalitis, using the latest available research and guidelines. It provides an overview of empiric antimicrobial treatment approaches for a variety of organisms, including a discussion of trends in antibiotic resistance where applicable. Key steps in diagnosis and general management are briefly reviewed.


1996 ◽  
Vol 9 (3) ◽  
pp. 107-119 ◽  
Author(s):  
Melinda S. Lantz ◽  
Deborah Marin

Agitated behaviors are a common and nearly universal occurrence among patients suffering from dementing illnesses. The pharmacologic treatments available for this troubling syndrome are varied, but treatment studies are limited. Clinicians are frequently faced with the challenging management of patients with disruptive behavior who fail to respond to trials with multiple agents. This review summarizes available treatment studies of agitation in dementia and offers a guide to therapy and management. Reports of therapies for agitation in dementia are limited by lack of controlled studies, variability of diagnostic criteria and outcome measures, and small sample size. The need for carefully designed, well-controlled studies of outcome in this growing population is formidable. It is imperative to identify effective and well-tolerated treatment strategies to reduce the morbidity of these distressing and burdensome symptoms.


2012 ◽  
Vol 15 (4) ◽  
pp. 499 ◽  
Author(s):  
Hoan Linh Banh

Delirium is a common manifestation of acute, reversible, brain dysfunction in critically ill patients. It is associated with increased morbidity and mortality in the intensive care unit (ICU). Detection and prevention of risk factors for delirium is critical. Daily assessment for delirium should be part of the treatment strategies. Although, non-pharmacologic treatment have been successful, often, pharmacologic intervention is necessary. Currently, there are no approved medications indicated for the treatment of ICU delirium. The objective of this review article is to provide a comprehensive overview of non-pharmacologic and pharmacologic options for the treatment of ICU delirium. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.


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