Determination of N 1,N 12-Diacetylspermine in Urine: A Novel Tumor Marker

2011 ◽  
pp. 367-378 ◽  
Author(s):  
Masao Kawakita ◽  
Kyoko Hiramatsu ◽  
Mari Yanagiya ◽  
Yosuke Doi ◽  
Mieko Kosaka
Keyword(s):  
Tumor Marker

scholarly journals Significance of Serial Determination of Tumor Marker with Reference to the Differential Diagnosis between Pancreatic Cancer and Tumor Forming Pancreatitis.

1992 ◽  
Vol 25 (5) ◽  
pp. 1222-1227
Author(s):  
Yoshito Yamashita ◽  
Young-Suk Chung ◽  
Hideaki Yokomatsu ◽  
Bunzo Nakata ◽  
Tetsuzi Sawada ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Differential Diagnosis ◽  
Tumor Marker ◽  
Serial Determination

Experimental pancreatic adenocarcinoma: An immunohistochemical study for CA 19-9 and its correlation with serum levels

1989 ◽  
Vol 4 (4) ◽  
pp. 229-232
Author(s):  
M. Abad ◽  
J.I. Paz ◽  
M.J. Pedraz ◽  
E. Muñoz ◽  
A. Bullón
Keyword(s):  
Tumor Marker ◽  
Pancreatic Carcinoma ◽  
Pancreatic Adenocarcinoma ◽  
Immunohistochemical Study ◽  
Serum Levels ◽  
Subcutaneous Injections ◽  
Syrian Hamsters ◽  
Important Correlation ◽  
Papillary Lesions

Experimental pancreatic carcinoma induced in Golden Syrian Hamsters by subcutaneous injections of N-nitrosobis-(2-oxopropyl) amine (BOP) was studied during the different phases of its development by determination of serum CA 19-9 levels and tissue labeling with CA 19-9 TM. Significant differences were observed in the CA 19-9 values between the controls and animals with carcinoma (p < 0.01) and between the latter and animals with cystic or cystic papillary lesions (p < 0.01). Distribution of the deposits of CA 19-9 TM was different in the initial tumoral lesions and in the longer-developed tumors. An important correlation was observed between tissue deposits and serum levels of this tumor marker.

The Determination of Urinary Oxypurines as Markers of Gastrointestinal Tumors

1987 ◽  
Vol 73 (3) ◽  
pp. 289-294 ◽  
Author(s):  
Marco Lorenzi ◽  
Daniela Vannoni ◽  
Roberto Leoncini ◽  
Ranieri Caldarone ◽  
Enrico Marinello
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
Urinary Excretion ◽  
Tumor Marker ◽  
Cancer Patients ◽  
Plasma Levels ◽  
Colorectal Tumor ◽  
Reverse Phase ◽  
Tumor Bearing

Plasma levels and urinary excretion of oxypurines – hypoxanthine and xanthine – were evaluated by reverse-phase high-pressure liquid chromatography in 13 patients affected by gastric tumors and in 19 colorectal tumor-bearing patients. Preliminary results indicate higher values of urinary xanthine and an increase in the xanthine/hypoxanthine ratio in cancer patients. The increase was not generalized to all subjects, and did not appear related either to the stage of the disease or to CEA values. The limits within which the determination of urinary oxypurines can be employed as a tumor marker are discussed.

Clinical Significance of the New Tumor Marker MCA in the follow-up of Patients with Mammary Carcinoma

1993 ◽  
Vol 8 (2) ◽  
pp. 130-132 ◽  
Author(s):  
J. Müller-Brand ◽  
H. Mäcke
Keyword(s):  
Breast Cancer ◽  
Serum Concentration ◽  
Tumor Marker ◽  
Mammary Carcinoma ◽  
Solid Phase ◽  
Clinical Status ◽  
Subsequent Increase ◽  
Degree Of Differentiation

MCA is a mucin-like carcinoma-associated antigen which has been found in all breast cancer independent of histological type and degree of differentiation. A two-step solid-phase EIA was developed and the serum concentration of MCA was measured in 176 breast cancer patiens after surgery. Using a cutoff of 11.0 U/ml the test showed a sensitivity of 77% and a specifity of 82% when compared to clinical status. The predictive value of this tumor marker was 72% for a positive diagnosis and 93% for a negative diagnosis. Based on these observations it is recommended that determination of MCA values take place 2 to 3 times in the first postoperative week in all women with surgically treated mammary carcinoma. These MCA values should then serve as reference for further determinations, which should be performed at each check-up. A subsequent increase in the MCA value should be considered as a first sign of metastasis.

Overview: Quality Control of Tumor Marker Assays

1998 ◽  
Vol 13 (4) ◽  
pp. 238-240
Author(s):  
R. Kruse ◽  
W.-J. Geilenkeuser ◽  
G. Röhle
Keyword(s):  
Quality Control ◽  
Tumor Marker ◽  
Ca 125 ◽  
Analytical Results ◽  
Commercial Kit

Data from interlaboratory surveys for the determination of CA 125 (1987 to 1998) show large differences depending on the commercial kit used. Samples of the same material produced different analytical results in different interlaboratory surveys, thus showing that some kits did not have a satisfactory rate of reproducibility over a longer period of time.

Direct determination of the tumor marker AFP via silver nanoparticle enhanced SERS and AFP-modified gold nanoparticles as capturing substrate

2018 ◽  
Vol 185 (2) ◽  
Author(s):  
Chenmeng Zhang ◽  
Yukun Gao ◽  
Nan Yang ◽  
Tingting You ◽  
Huaxiang Chen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Tumor Marker ◽  
Silver Nanoparticle ◽  
Direct Determination

NIR-II emissive lateral flow immunoassay for accurate determination of tumor marker in hemolysis

2021 ◽  
Vol 328 ◽  
pp. 129050
Author(s):  
Rui Chen ◽  
Xiaobo Zhou ◽  
Yong Wu ◽  
Qingyun Liu ◽  
Qian Liu ◽  
...  
Keyword(s):  
Tumor Marker ◽  
Accurate Determination ◽  
Lateral Flow ◽  
Lateral Flow Immunoassay

Phytic acid-based copper(ii) ion-selective electrode on graphene oxide for potentiometric immunoassay of breast cancer antigen 15-3

2019 ◽  
Vol 43 (28) ◽  
pp. 11171-11177 ◽  
Author(s):  
Min Zheng ◽  
Yong-Jin Cao ◽  
Wei-Hua Cai ◽  
Xi Shi ◽  
Mou-Feng Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Graphene Oxide ◽  
Quantitative Determination ◽  
Tumor Marker ◽  
Phytic Acid ◽  
Carbohydrate Antigen ◽  
Ion Selective Electrode ◽  
Selective Electrode ◽  
Cancer Antigen

A potentiometric immunoassay based on a copper(ii) ion-selective electrode (Cu-ISE) was designed for the quantitative determination of carbohydrate antigen 15-3 (CA 15-3; a tumor marker associated with breast cancer).

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