Large-Scale, High-Resolution Microelectrode Arrays for Interrogation of Neurons and Networks

Author(s):  
Marie Engelene J. Obien ◽  
Urs Frey
2014 ◽  
Vol 31 (2) ◽  
Author(s):  
Mariela Gabioux ◽  
Vladimir Santos da Costa ◽  
Joao Marcos Azevedo Correia de Souza ◽  
Bruna Faria de Oliveira ◽  
Afonso De Moraes Paiva

Results of the basic model configuration of the REMO project, a Brazilian approach towards operational oceanography, are discussed. This configuration consists basically of a high-resolution eddy-resolving, 1/12 degree model for the Metarea V, nested in a medium-resolution eddy-permitting, 1/4 degree model of the Atlantic Ocean. These simulations performed with HYCOM model, aim for: a) creating a basic set-up for implementation of assimilation techniques leading to ocean prediction; b) the development of hydrodynamics bases for environmental studies; c) providing boundary conditions for regional domains with increased resolution. The 1/4 degree simulation was able to simulate realistic equatorial and south Atlantic large scale circulation, both the wind-driven and the thermohaline components. The high resolution simulation was able to generate mesoscale and represent well the variability pattern within the Metarea V domain. The BC mean transport values were well represented in the southwestern region (between Vitória-Trinidade sea mount and 29S), in contrast to higher latitudes (higher than 30S) where it was slightly underestimated. Important issues for the simulation of the South Atlantic with high resolution are discussed, like the ideal place for boundaries, improvements in the bathymetric representation and the control of bias SST, by the introducing of a small surface relaxation. In order to make a preliminary assessment of the model behavior when submitted to data assimilation, the Cooper & Haines (1996) method was used to extrapolate SSH anomalies fields to deeper layers every 7 days, with encouraging results.


2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Chris E. Blenkinsopp ◽  
Paul M. Bayle ◽  
Daniel C. Conley ◽  
Gerd Masselink ◽  
Emily Gulson ◽  
...  

A Correction to this paper has been published: https://doi.org/10.1038/s41597-021-00874-2.


2021 ◽  
Vol 13 (15) ◽  
pp. 2877
Author(s):  
Yu Tao ◽  
Siting Xiong ◽  
Susan J. Conway ◽  
Jan-Peter Muller ◽  
Anthony Guimpier ◽  
...  

The lack of adequate stereo coverage and where available, lengthy processing time, various artefacts, and unsatisfactory quality and complexity of automating the selection of the best set of processing parameters, have long been big barriers for large-area planetary 3D mapping. In this paper, we propose a deep learning-based solution, called MADNet (Multi-scale generative Adversarial u-net with Dense convolutional and up-projection blocks), that avoids or resolves all of the above issues. We demonstrate the wide applicability of this technique with the ExoMars Trace Gas Orbiter Colour and Stereo Surface Imaging System (CaSSIS) 4.6 m/pixel images on Mars. Only a single input image and a coarse global 3D reference are required, without knowing any camera models or imaging parameters, to produce high-quality and high-resolution full-strip Digital Terrain Models (DTMs) in a few seconds. In this paper, we discuss technical details of the MADNet system and provide detailed comparisons and assessments of the results. The resultant MADNet 8 m/pixel CaSSIS DTMs are qualitatively very similar to the 1 m/pixel HiRISE DTMs. The resultant MADNet CaSSIS DTMs display excellent agreement with nested Mars Reconnaissance Orbiter Context Camera (CTX), Mars Express’s High-Resolution Stereo Camera (HRSC), and Mars Orbiter Laser Altimeter (MOLA) DTMs at large-scale, and meanwhile, show fairly good correlation with the High-Resolution Imaging Science Experiment (HiRISE) DTMs for fine-scale details. In addition, we show how MADNet outperforms traditional photogrammetric methods, both on speed and quality, for other datasets like HRSC, CTX, and HiRISE, without any parameter tuning or re-training of the model. We demonstrate the results for Oxia Planum (the landing site of the European Space Agency’s Rosalind Franklin ExoMars rover 2023) and a couple of sites of high scientific interest.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Peipei Du ◽  
Jinghui Li ◽  
Liang Wang ◽  
Liang Sun ◽  
Xi Wang ◽  
...  

AbstractWith rapid advances of perovskite light-emitting diodes (PeLEDs), the large-scale fabrication of patterned PeLEDs towards display panels is of increasing importance. However, most state-of-the-art PeLEDs are fabricated by solution-processed techniques, which are difficult to simultaneously achieve high-resolution pixels and large-scale production. To this end, we construct efficient CsPbBr3 PeLEDs employing a vacuum deposition technique, which has been demonstrated as the most successful route for commercial organic LED displays. By carefully controlling the strength of the spatial confinement in CsPbBr3 film, its radiative recombination is greatly enhanced while the nonradiative recombination is suppressed. As a result, the external quantum efficiency (EQE) of thermally evaporated PeLED reaches 8.0%, a record for vacuum processed PeLEDs. Benefitting from the excellent uniformity and scalability of the thermal evaporation, we demonstrate PeLED with a functional area up to 40.2 cm2 and a peak EQE of 7.1%, representing one of the most efficient large-area PeLEDs. We further achieve high-resolution patterned perovskite film with 100 μm pixels using fine metal masks, laying the foundation for potential display applications. We believe the strategy of confinement strength regulation in thermally evaporated perovskites provides an effective way to process high-efficiency and large-area PeLEDs towards commercial display panels.


2019 ◽  
Vol 15 (S359) ◽  
pp. 312-317
Author(s):  
Francoise Combes

AbstractGas fueling AGN (Active Galaxy Nuclei) is now traceable at high-resolution with ALMA (Atacama Large Millimeter Array) and NOEMA (NOrthern Extended Millimeter Array). Dynamical mechanisms are essential to exchange angular momentum and drive the gas to the super-massive black hole. While at 100pc scale, the gas is sometimes stalled in nuclear rings, recent observations reaching 10pc scale (50mas), may bring smoking gun evidence of fueling, within a randomly oriented nuclear gas disk. AGN feedback is also observed, in the form of narrow and collimated molecular outflows, which point towards the radio mode, or entrainment by a radio jet. Precession has been observed in a molecular outflow, indicating the precession of the radio jet. One of the best candidates for precession is the Bardeen-Petterson effect at small scale, which exerts a torque on the accreting material, and produces an extended disk warp. The misalignment between the inner and large-scale disk, enhances the coupling of the AGN feedback, since the jet sweeps a large part of the molecular disk.


2012 ◽  
Vol 8 (S292) ◽  
pp. 199-208 ◽  
Author(s):  
Susanne Aalto

AbstractStudying the molecular phase of the interstellar medium in galaxies is fundamental for the understanding of the onset and evolution of star formation and the growth of supermassive black holes. We can use molecules as observational tools exploiting them as tracers of chemical, physical and dynamical conditions. In this short review, key molecules (e.g. HCN, HCO+, HNC, HC3N, CN, H3O+) in identifying the nature of buried activity and its evolution are discussed including some standard astrochemical scenarios. Furthermore, we can use IR excited molecular emission to probe the very inner regions of luminous infrared galaxies (LIRGs) allowing us to get past the optically thick dust barrier of the compact obscured nuclei, e.g. in the dusty LIRG NGC4418. High resolution studies are often necessary to separate effects of excitation and radiative transport from those of chemistry - one example is absorption and effects of stimulated emission in the ULIRG Arp220. Finally, molecular gas in large scale galactic outflows is briefly discussed.


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