Natural Products as Immunomodulatory and Chemosensitizing Agents in Colon Cancer Treatment

2021 ◽  
pp. 187-207
Author(s):  
Sandeep Kumar ◽  
Abhishek Goel ◽  
Yogendra S. Padwad
1999 ◽  
Vol 23 (5) ◽  
pp. 428-434 ◽  
Author(s):  
Sarah E. Tropman ◽  
Theresa Hatzell ◽  
Electra Paskett ◽  
Thomas Ricketts ◽  
M. robert Cooper ◽  
...  

2020 ◽  
Vol 231 (4) ◽  
pp. S55-S56
Author(s):  
Scarlett B. Hao ◽  
Rebecca A. Snyder ◽  
William Irish ◽  
Alexander A. Parikh

2018 ◽  
Vol 73 (1) ◽  
pp. 34-41 ◽  
Author(s):  
Louise Hayes ◽  
Lynne Forrest ◽  
Jean Adams ◽  
Mira Hidajat ◽  
Yoav Ben-Shlomo ◽  
...  

BackgroundOlder people experience poorer outcomes from colon cancer. We examined if treatment for colon cancer was related to age and if inequalities changed over time.MethodsData from the UK population-based Northern and Yorkshire Cancer Registry on 31 910 incident colon cancers (ICD10 C18) diagnosed between 1999–2010 were obtained. Likelihood of receipt of: (1) cancer-directed surgery, (2) chemotherapy in surgical patients, (3) chemotherapy in non-surgical patients by age, adjusting for sex, area deprivation, cancer stage, comorbidity and period of diagnosis, was examined.ResultsAge-related inequalities in treatment exist after adjustment for confounding factors. Patients aged 60– 69, 70–79 and 80+ years were significantly less likely to receive surgery than those aged <60 years (multivariable ORs (95% CI) 0.84(0.74 to 0.95), 0.54(0.48 to 0.61) and 0.19(0.17 to 0.21), respectively). Age-related differences in receipt of surgery and adjuvant chemotherapy (but not chemotherapy in non-surgical patients) narrowed over time for the ’younger old’ (aged <80 years) but did not diminish for the oldest patients.ConclusionsAge inequality in treatment of colon cancer remains after adjustment for confounders, suggesting age remains a major factor in treatment decisions. Research is needed to better understand the cancer treatment decision-making process, and how to influence this, for older patients.


2015 ◽  
Vol 32 (8) ◽  
pp. 1170-1182 ◽  
Author(s):  
A. AlQathama ◽  
J. M. Prieto

Natural products continue to provide lead cytotoxic compounds for cancer treatment but less attention has been given to antimigratory compounds. We here systematically and critically survey more than 30 natural products with direct in vitro and in vivo pharmacological effects on migration and/or metastasis of melanoma cells and chart the mechanisms of action for this underexploited property.


2017 ◽  
Vol 32 (3) ◽  
pp. 571-579 ◽  
Author(s):  
Nicole Ernstmann ◽  
Markus Wirtz ◽  
Anika Nitzsche ◽  
Sophie E. Gross ◽  
Lena Ansmann ◽  
...  

Nanomedicine ◽  
2021 ◽  
Author(s):  
Firdos Alam Khan ◽  
Razan Aldahhan ◽  
Dana Almohazey

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