Is Decreasing Sperm Concentrations a Sign of a General Decay in Fertility Potential?

Author(s):  
Lars Björndahl
1998 ◽  
Vol 16 (2) ◽  
pp. 733-734 ◽  
Author(s):  
H W Herr ◽  
N Bar-Chama ◽  
M O'Sullivan ◽  
P C Sogani

PURPOSE We report long-term paternity in men with stage I testis tumors who were managed initially by surveillance. PATIENTS AND METHODS One hundred five patients with clinical stage I nonseminomatous germ cell tumors of the testis were entered on a surveillance protocol and followed up for more than 10 years. Actual fertility potential was assessed by pregnancy. RESULTS Of the 105 patients, 41 (39%) have fathered children, which includes 36 of 78 (46%) patients while on active surveillance and five of 27 (19%) patients after treatment for relapse. Of 63 couples who attempted a pregnancy on surveillance or were presumed capable of impregnation (whether they tried or not), 41 (65%) were successful. CONCLUSION These results show that the majority of men with stage I testis tumor who are on surveillance after orchiectomy, have a suitable partner, and attempt impregnation achieve a successful pregnancy. Pregnancy rates appear to be less than reported in men who have a nerve-sparing retroperitoneal lymph node dissection (RPLND) because more patients on surveillance require treatment for relapse, which reduces their chances for pregnancy.


Author(s):  
Nabil A. Khouri ◽  
Haytham M. Daradka ◽  
Mohammed Z. Allouh ◽  
Ahmad S. Alkofahi

Abstract: The effects of: Both plants were administered orally to two separate mice groups at a dose of 800 mg/kg/day for 35 days and compared with control group. After treatment, 5 mice of each group were sacrificed and total mice weights, reproductive organs’ weights, spermatogenesis, and androgenic serum markers were investigated. The remaining mice from all groups were allowed to mate with virgin female mice to explore male fertility potential.: Results indicated that body and organs’ weights were increased significantly in mice treated with: We can conclude that


2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
Mohammad M. Al-Gharabli ◽  
Adel M. Al-Mahdi ◽  
Salim A. Messaoudi

Abstract This work is concerned with a system of two singular viscoelastic equations with general source terms and nonlocal boundary conditions. We discuss the stabilization of this system under a very general assumption on the behavior of the relaxation function $k_{i}$ k i , namely, $$\begin{aligned} k_{i}^{\prime }(t)\le -\xi _{i}(t) \Psi _{i} \bigl(k_{i}(t)\bigr),\quad i=1,2. \end{aligned}$$ k i ′ ( t ) ≤ − ξ i ( t ) Ψ i ( k i ( t ) ) , i = 1 , 2 . We establish a new general decay result that improves most of the existing results in the literature related to this system. Our result allows for a wider class of relaxation functions, from which we can recover the exponential and polynomial rates when $k_{i}(s) = s^{p}$ k i ( s ) = s p and p covers the full admissible range $[1, 2)$ [ 1 , 2 ) .


2021 ◽  
Vol 500 (1) ◽  
pp. 125136
Author(s):  
Adel M. Al-Mahdi ◽  
Mohammad M. Al-Gharabli ◽  
Salim A. Messaoudi

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Sarah E. Moorey ◽  
Fernando H. Biase

Abstract The development of replacement heifers is at the core of cow-calf beef production systems. In 2020, the USDA, National Agricultural Statistics Service reported 5.771 million beef heifers, 500 pounds and over, are under development for cow replacement. A compilation of data from several studies indicate that between 85% and 95% of these heifers will become pregnant in their first breeding season. Several thousands of heifers being raised for replacement may not deliver a calf on their first breeding season and result in economic losses to cow-calf producers. Many management procedures have been developed to maximize the reproductive potential of beef heifers. Such approaches include, but are not limited to the following: nutritional management for controlled weight gain, identification of reproductive maturity by physiological and morphological indicators, and the implementation of an estrous synchronization program. The implementation of management strategies has important positive impact(s) on the reproductive efficiency of heifers. There are limitations, however, because some heifers deemed ready to enter their first breeding season do not become pregnant. In parallel, genetic selection for fertility-related traits in beef heifers have not promoted major genetic gains on this particular area, most likely due to low heritability of female fertility traits in cattle. Technologies such as antral follicle counting, DNA genotyping and RNA profiling are being investigated as a means to aid in the identification of heifers of low fertility potential. To date, many polymorphisms have been associated with heifer fertility, but no DNA markers have been identified across herds. Antral follicle count is an indication of the ovarian reserve and is an indicator of the reproductive health of a heifer. We have been working on the identification of transcriptome profiles in heifers associated with pregnancy outcome. Our current investigations integrating protein-coding transcript abundance and artificial intelligence have identified the potential for bloodborne transcript abundance to be used as indicators of fertility potential in beef heifers. In summary, there is an ongoing pressure for reducing costs and increasing efficiency in cow-calf production systems, and new technologies can help reduce the long-standing limitations in beef heifer fertility.


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