Soft Matter Systems for Biomedical Applications

2022 ◽  
Macromol ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 155-172
Author(s):  
Aristeidis Papagiannopoulos

Polyelectrolytes have been at the center of interdisciplinary research for many decades. In the field of polymer science and soft matter, they have provided the dimensions of electrostatic interactions, which opens a vast variety of opportunities for new physical properties and applications. In biological matter, polyelectrolytes are present in many forms, from extracellular polysaccharides to complex DNA molecules and proteins. This review discusses the recent research on polyelectrolytes covering the fundamental level of their conformations and nanostructures, their molecular interactions with materials that have close relevance to bioapplications and their applications in the biomedical field. This approach is motivated by the fact that the polyelectrolyte research is constantly active in all the aforementioned levels and continually affects many critical scientific areas.


2017 ◽  
Vol 20 (2) ◽  
pp. 134-141 ◽  
Author(s):  
A. S. Lozhkomoev ◽  
M. I. Lerner ◽  
A. A. Tsukanov ◽  
S. O. Kazantsev ◽  
O. V. Bakina ◽  
...  

Matter ◽  
2019 ◽  
Vol 1 (5) ◽  
pp. 1127-1147 ◽  
Author(s):  
Adrianna N. Shy ◽  
Beom Jin Kim ◽  
Bing Xu

Nanoscale ◽  
2016 ◽  
Vol 8 (38) ◽  
pp. 16819-16840 ◽  
Author(s):  
Meiying Liu ◽  
Guangjian Zeng ◽  
Ke Wang ◽  
Qing Wan ◽  
Lei Tao ◽  
...  

Recent progress and advances in mussel-inspired surface modification strategies and the biomedical applications of polydopamine-based materials are summarized in this review.


2001 ◽  
Vol 7 (S2) ◽  
pp. 132-133
Author(s):  
D.J. Stokes ◽  
S.M. Rea ◽  
A.E. Porter ◽  
S.M. Best ◽  
W. Bonfield

The ability of ESEM to image insulating and/or moist specimens without the need for the removal of volatile components or the application of a conductive coating has significantly increased the potential range of experiments and observations that can be performed at the high resolution of electron microscopy. Such a technological advance has particularly important implications for the study of soft matter, complex fluids and biological specimens.An important area of study to which ESEM can be readily applied is that of materials for biomedical applications. Hydroxyapatite (HA) ceramics and HA/polymer composites (e.g. HAPEX™) are being developed for use as synthetic scaffolds in bone tissue engineering. The bioactivity of these materials is dependent upon such factors as phase composition, chemical composition, surface activity, crystallinity and microstructure. Using ESEM it is possible to obtain surface-sensitive, specimen-dependent secondary electron images (in the absence of specimen coating), yielding potentially new perspectives on microstructure to complement information derived from other techniques.


2018 ◽  
Vol 116 (1) ◽  
pp. 84-89 ◽  
Author(s):  
Asier Marzo ◽  
Bruce W. Drinkwater

Acoustic tweezers use sound radiation forces to manipulate matter without contact. They provide unique characteristics compared with the more established optical tweezers, such as higher trapping forces per unit input power and the ability to manipulate objects from the micrometer to the centimeter scale. They also enable the trapping of a wide range of sample materials in various media. A dramatic advancement in optical tweezers was the development of holographic optical tweezers (HOT) which enabled the independent manipulation of multiple particles leading to applications such as the assembly of 3D microstructures and the probing of soft matter. Now, 20 years after the development of HOT, we present the realization of holographic acoustic tweezers (HAT). We experimentally demonstrate a 40-kHz airborne HAT system implemented using two 256-emitter phased arrays and manipulate individually up to 25 millimetric particles simultaneously. We show that the maximum trapping forces are achieved once the emitting array satisfies Nyquist sampling and an emission phase discretization below π/8 radians. When considered on the scale of a wavelength, HAT provides similar manipulation capabilities as HOT while retaining its unique characteristics. The examples shown here suggest the future use of HAT for novel forms of displays in which the objects are made of physical levitating voxels, assembly processes in the micrometer and millimetric scale, as well as positioning and orientation of multiple objects which could lead to biomedical applications.


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