Global Burden of Surgical Disease and the Role of Academia

Author(s):  
Doruk Ozgediz ◽  
Keith P. Martin ◽  
Emmanuel A. Ameh
2011 ◽  
Vol 127 (2) ◽  
pp. 1019-1020 ◽  
Author(s):  
Anup Patel ◽  
Indranil Sinha ◽  
Mark McRae ◽  
Niclas Broer ◽  
James Watkins ◽  
...  

2020 ◽  
Vol 162 (3) ◽  
pp. 296-303 ◽  
Author(s):  
Rolvix H. Patterson ◽  
Victoria G. Fischman ◽  
Isaac Wasserman ◽  
Jennifer Siu ◽  
Mark G. Shrime ◽  
...  

Objective We aimed to describe the mortality burden and macroeconomic effects of head and neck cancer as well as delineate the role of surgical workforce in improving head and neck cancer outcomes. Study Design Statistical and economic analysis. Setting Research group. Subjects and Methods We conducted a statistical analysis on data from the World Development Indicators and the 2016 Global Burden of Disease study to describe the relationship between surgical workforce and global head and neck cancer mortality-to-incidence ratios. A value of lost output model was used to project the global macroeconomic effects of head and neck cancer. Results Significant differences in mortality-to-incidence ratios existed between Global Burden of Disease study superregions. An increase of surgical, anesthetic, and obstetric provider density by 10% significantly correlated with a reduction of 0.76% in mortality-to-incidence ratio ( P < .0001; adjusted R2 = 0.84). There will be a projected global cumulative loss of $535 billion US dollars (USD) in economic output due to head and neck cancer between 2018 and 2030. Southeast Asia, East Asia, and Oceania will suffer the greatest gross domestic product (GDP) losses at $180 billion USD, and South Asia will lose $133 billion USD. Conclusion The mortality burden of head and neck cancer is increasing and disproportionately affects those in low- and middle-income countries and regions with limited surgical workforces. This imbalance results in large and growing economic losses in countries that already face significant resource constraints. Urgent investment in the surgical workforce is necessary to ensure access to timely surgical services and reverse these negative trends.


2017 ◽  
Vol 47 ◽  
pp. S68-S69
Author(s):  
F. Ahmed ◽  
N. Chaudhry ◽  
Z. Abdi ◽  
S. Shami ◽  
A. Shah ◽  
...  

2012 ◽  
Vol 37 (3) ◽  
pp. 498-503 ◽  
Author(s):  
Jessica H. Beard ◽  
Lawrence B. Oresanya ◽  
Michael Ohene-Yeboah ◽  
Rochelle A. Dicker ◽  
Hobart W. Harris

2022 ◽  
Vol 12 ◽  
Author(s):  
J. P. Jose Merlin ◽  
Xiaogang Li

Nanoparticles (NPs) are differing in particle size, charge, shape, and compatibility of targeting ligands, which are linked to improved pharmacologic characteristics, targetability, and bioavailability. Researchers are now tasked with developing a solution for enhanced renal treatment that is free of side effects and delivers the medicine to the active spot. A growing number of nano-based medication delivery devices are being used to treat renal disorders. Kidney disease management and treatment are currently causing a substantial global burden. Renal problems are multistep processes involving the accumulation of a wide range of molecular and genetic alterations that have been related to a variety of kidney diseases. Renal filtration is a key channel for drug elimination in the kidney, as well as a burgeoning topic of nanomedicine. Although the use of nanotechnology in the treatment of renal illnesses is still in its early phases, it offers a lot of potentials. In this review, we summarized the properties of the kidney and characteristics of drug delivery systems, which affect a drug’s ability should focus on the kidney and highlight the possibilities, problems, and opportunities.


2020 ◽  
Vol 44 (7) ◽  
pp. 2139-2143
Author(s):  
Brittany L. Powell ◽  
Rebecca Luckett ◽  
Abebe Bekele ◽  
Tiffany E. Chao

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