scholarly journals Correction to: Advances in Early Detection and Diagnostic Adjuncts in Oral Cavity Cancer

2020 ◽  
pp. C3-C4
Author(s):  
Camile S. Farah ◽  
Nirav Bhatia ◽  
Yastira Lalla ◽  
An Vu ◽  
Keziah John ◽  
...  
2016 ◽  
pp. 355-421 ◽  
Author(s):  
Camile S. Farah ◽  
Nirav Bhatia ◽  
Yastira Lalla ◽  
An Vu ◽  
Keziah John ◽  
...  

2020 ◽  
Vol 58 (225) ◽  
Author(s):  
Gambhir Shrestha ◽  
Leison Maharjan

Oral cavity cancer is one of the most common preventable cancers in the world. The burden of thedisease is high in South Asia. Therefore, public health strategies such as creating awareness anddisease screening should be advocated for its prevention and early detection. Mouth self-examinationserves both the purposes. It is easy to perform, non-invasive, and low-cost methods. It not only helpsin the early detection of suspicious oral lesions but also helps people to quit their high-risk behaviorssuch as consumption of tobacco and alcohol.


Oral Diseases ◽  
2021 ◽  
Author(s):  
Ku‐Hao Fang ◽  
Sheng‐Wei Chang ◽  
Yi‐Chan Lee ◽  
Ethan I Huang ◽  
Chia‐Hsuan Lai ◽  
...  

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2674
Author(s):  
Tessa Buckle ◽  
Maarten van Alphen ◽  
Matthias N. van Oosterom ◽  
Florian van Beurden ◽  
Nina Heimburger ◽  
...  

Intraoperative tumor identification (extension/margins/metastases) via receptor-specific targeting is one of the ultimate promises of fluorescence-guided surgery. The translation of fluorescent tracers that enable tumor visualization forms a critical component in the realization of this approach. Ex vivo assessment of surgical specimens after topical tracer application could help provide an intermediate step between preclinical evaluation and first-in-human trials. Here, the suitability of the c-Met receptor as a potential surgical target in oral cavity cancer was explored via topical ex vivo application of the fluorescent tracer EMI-137. Freshly excised tumor specimens obtained from ten patients with squamous cell carcinoma of the tongue were incubated with EMI-137 and imaged with a clinical-grade Cy5 prototype fluorescence camera. In-house developed image processing software allowed video-rate assessment of the tumor-to-background ratio (TBR). Fluorescence imaging results were related to standard pathological evaluation and c-MET immunohistochemistry. After incubation with EMI-137, 9/10 tumors were fluorescently illuminated. Immunohistochemistry revealed c-Met expression in all ten specimens. Non-visualization could be linked to a more deeply situated lesion. Tumor assessment was improved via video representation of the TBR (median TBR: 2.5 (range 1.8–3.1)). Ex vivo evaluation of tumor specimens suggests that c-Met is a possible candidate for fluorescence-guided surgery in oral cavity cancer.


2008 ◽  
Vol 29 (4) ◽  
pp. 318-322 ◽  
Author(s):  
Girolamo Tartaglione ◽  
Maurizio G. Vigili ◽  
Siavash Rahimi ◽  
Alessandra Celebrini ◽  
Marco Pagan ◽  
...  

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