Antimicrobial Resistance: An International Public Health Problem

2017 ◽  
pp. 1519-1528 ◽  
Author(s):  
Joseph D. Lutgring ◽  
Carlos A. Diaz Granados ◽  
John E. McGowan
Keyword(s):  
Public Health ◽  
Antimicrobial Resistance ◽  
Health Problem ◽  
Public Health Problem ◽  
International Public Health

Antimicrobial Resistance of Campylobacter jejuni Isolated from Chicken Carcasses in the Federal District, Brazil

2013 ◽  
Vol 76 (4) ◽  
pp. 691-693 ◽  
Author(s):  
HELENIRA MELO de MOURA ◽  
PATRÍCIA RENAULT SILVA ◽  
PATRÍCIA HELENA CALDEIRA da SILVA ◽  
NARA RÚBIA SOUZA ◽  
ALINE MONDINI C. RACANICCI ◽  
...  
Keyword(s):  
Public Health ◽  
Antimicrobial Resistance ◽  
Nalidixic Acid ◽  
Campylobacter Jejuni ◽  
Health Problem ◽  
Food Processing ◽  
Public Health Problem ◽  
Federal District ◽  
Antimicrobial Drugs ◽  
High Level

The aim of the present study was to perform microbiological isolation of Campylobacter jejuni from chilled chicken carcasses marketed in the Federal District of Brazil and to subject the strains to an antibiogram. A total of 92 samples from chilled chicken carcasses were acquired, 18 of which (19.56%) tested positive for C. jejuni. A total of 16 strains were tested for susceptibility to eight antimicrobial drugs. All 16 strains were resistant to ciprofloxacin, 15 strains to nalidixic acid, streptomycin, tetracycline, and gentamycin, 14 strains to amoxicillin, 11 strains to erythromycin, and 6 strains to chloramphenicol. The present study is the first to report on the presence of C. jejuni in chilled chicken carcasses marketed in the Federal District region of Brazil. These results may indicate flaws in certain steps of this food processing and highlight a possible public health problem due to the high level of resistance exhibited by the isolated strains.

scholarly journals Editorial: Antimicrobial Resistance as a Global Public Health Problem: How Can We Address It?

2020 ◽  
Vol 8 ◽  
Author(s):  
Luciene Andrade Da Rocha Minarini ◽  
Leonardo Neves de Andrade ◽  
Eliana De Gregorio ◽  
Filipa Grosso ◽  
Thierry Naas ◽  
...  
Keyword(s):  
Public Health ◽  
Antimicrobial Resistance ◽  
Health Problem ◽  
Public Health Problem ◽  
Global Public Health ◽  
Global Public Health Problem

scholarly journals A review on Antibiotic Policy and Antimicrobial Stewardship Program (AMSP) – Need of the hour

2021 ◽  
Vol 12 (2) ◽  
pp. 1233-1237
Author(s):  
Manoj Kumar ◽  
Anu Sharma ◽  
Yasmeen M ◽  
Parwez
Keyword(s):  
Public Health ◽  
Antimicrobial Resistance ◽  
Antimicrobial Stewardship ◽  
Health Problem ◽  
Public Health Problem ◽  
Current Situation ◽  
Resistant Bacteria ◽  
Antimicrobial Stewardship Program ◽  
Antibiotic Policy ◽  
Stewardship Program

Emerging trends of antimicrobial resistance and development of multidrug resistance and pan resistant strains have become a significant public health problem worldwide. The rate at which newer drugs are developing has slowed down and clinicians are left with only limited therapeutic options for treatment of the patient. We are heading towards the pre antibiotic discovery phase where mortality was high due to unavailability of appropriate drugs; however, in current situation due to misuse or over use of antibiotics, microbes have developed newer methods of resistance, thus rendering these antimicrobials ineffective in their action which has resulted in increased morbidity and mortality among patient and increase in the health care expenditure. Antimicrobial resistance continues to be a major public health problem of international concern. As there is alarming situation globally due to development of multi and pan resistant bacteria which are also known as superbugs, these superbugs have resulted in havoc as these infections are not treatable and is of great concern to the treating physician. Judicious use of antibiotics and implementation of antibiotic stewardship program are the only ways to combat the current situation. The present review aims to provide information on framing of antibiotic policy and implementation of antimicrobial stewardship program.      

Detection of Antibiotic Resistance in Escherichia coli Strains: Can Fish Commonly Used in Raw Preparations such as Sushi and Sashimi Constitute a Public Health Problem?

2019 ◽  
Vol 82 (7) ◽  
pp. 1130-1134 ◽  
Author(s):  
VANESSA SILVA ◽  
JOÃO NUNES ◽  
ANÍCIA GOMES ◽  
ROSA CAPITA ◽  
CARLOS ALONSO-CALLEJA ◽  
...  
Keyword(s):  
Public Health ◽  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Antimicrobial Resistance ◽  
Health Problem ◽  
Antibiotic Resistance Genes ◽  
Public Health Problem ◽  
Commercial Fish ◽  
E Coli ◽  
Raw Fish

ABSTRACT We studied 50 antimicrobial resistance mechanisms associated with Escherichia coli strains isolated from five species of commercial fish to evaluate the carriage and type of extended-spectrum β-lactamases (ESBLs) in these isolates. One hundred fifty samples of fresh raw fish were collected from large supermarkets and fish markets in northern Portugal during 2017. Thirty samples from each species were screened for the presence of E. coli and ESBL-producing E. coli. The samples were spread onto Levine plates with or without cefotaxime (2 μg/mL). The sensitivity of the isolates was determined for 16 antibiotics. The resistance and virulence genes were investigated by PCR. From the 150 samples, 45 E. coli isolates were recovered, and 3 of these isolates produced ESBL. All of these ESBL-producing isolates were resistant to β-lactams and harbored the blaCTX-M-1 and blaTEM genes, and all belonged to phylogenetic group A. One ESBL-producing E. coli isolate also was resistant to tetracycline and harbored the tet(A) gene, and another isolate was resistant to streptomycin and harbored the aadA gene. The remaining E. coli isolates were resistant to individual or combinations of the following antibiotics: tetracycline (16 isolates), sulfamethoxazole-trimethoprim (10 isolates), streptomycin (9 isolates), ampicillin (8 isolates), and chloramphenicol (2 isolates). The blaTEM, tet(A), aadA, and cmlA genes and combinations of sul genes were detected among most isolates that were resistant to ampicillin, tetracycline, streptomycin, chloramphenicol, and sulfamethoxazole-trimethoprim, respectively. The unmonitored and excessive use of antibiotics in aquatic environments promotes the development and propagation of antimicrobial resistance, and fish can be reservoirs of antibiotic resistance genes, which can easily be transmitted to humans through the consumption of raw fish, creating a public health problem. HIGHLIGHTS

Sign in / Sign up

Export Citation Format

Share Document