In Vitro Studies, Biosynthesis of Secondary Metabolites and Pharmacological Utility of Catharanthus roseus (L.) G. Don.: A Review

2017 ◽  
pp. 153-199 ◽  
Author(s):  
P. Senbagalakshmi ◽  
M. V. Rao ◽  
T. Senthil Kumar
Keyword(s):  
Secondary Metabolites ◽  
Catharanthus Roseus ◽  
In Vitro Studies

In vitro Production of Secondary Metabolites Using Elicitor in Catharanthus roseus: A Case Study

2013 ◽  
pp. 401-419 ◽  
Author(s):  
Zahid Hameed Siddiqui ◽  
Abdul Mujib ◽  
Mahmooduzzafar ◽  
Junaid Aslam ◽  
Khalid Rehman Hakeem ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Catharanthus Roseus ◽  
In Vitro Production ◽  
Vitro Production

scholarly journals Influence of L-Tryptophan and salicylic acid on secondary metabolites production from leaves induced callus of Catharanthus roseus L.G.Don in vitro

2014 ◽  
Vol 8 (2) ◽  
pp. 35-43
Author(s):  
Emad H. Jassim ◽  
Sami K. M. Ameen
Keyword(s):  
Salicylic Acid ◽  
Secondary Metabolites ◽  
Catharanthus Roseus ◽  
Leaf Explants ◽  
Ms Medium ◽  
Plant Leaves ◽  
Fresh Weight ◽  
Metabolites Production ◽  
Different Levels

An experiment was conducted to steady the effect of L-Tryptophan and salicylic acid on callus induced on leaf explants of Catharanthus roseus. Callus induction was achieved by culturing true leaves of the plant on Murashige and Skoog (MS) medium supplemented with 0.5 mg /L 2,4-D and 1mg / L Kin. The best medium to maintain callus was MS medium supplemented with 0.5 mg /L 2,4-D and 1.5 mg / L Kin. Different levels added to MS medium for each L-Tryptophan 0,200,300or400 mg /L and salicylic acid 0, 0.5,1or1.5mg /L. The medium supplemented with 30 g/ L sucrose was used as a control. Results showed the medium supplemented with 200 mgL of L-Tryptophan gave the highest quantity of Vincristine reached 48.66 µg/100 fresh weight of callus. MS medium content at the concentration 1 mg L of salicylic acid gave the highest level of Vinblastine recording 50.98 µg/100 fresh weight of callus. While MS medium supplemented with 0.5 mg /L of salicylic acid gave the highest level of Serpentine 24.76 µg/100 fresh weight of callus. The concentrations of active compound derived from plant leaves were much less than the concentrations produced by the callus grown in vitro. The concentration of Serpentine was 0.059 while Vinblastine was 0.183 and the concentration of Vincristine was 0.064.

scholarly journals Activities of Tannins – from in Vitro Studies to Clinical Trials

2015 ◽  
Vol 10 (11) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Elwira Sieniawska
Keyword(s):  
Clinical Trials ◽  
Secondary Metabolites ◽  
Human Health ◽  
Laboratory Tests ◽  
Plant Secondary Metabolites ◽  
In Vitro Studies ◽  
Literature Research ◽  
Wide Range

Tannins are considered as valuable plant secondary metabolites providing many benefits for human health. In this review information was gathered about bioactivity in vitro and in vivo, as well as about conducted clinical trials. The literature research was based on ScienceDirect, Scopus, and Cochrane databases and presents a wide range of tested activities of tannins. The described clinical trials verify laboratory tests and show the effective health benefits taken from supplementation with tannins.

Effect of the medium pH on the release of secondary metabolites from roots ofDatura stramonium, Catharanthus roseus, andTagetes patula cultured in vitro

1993 ◽  
Vol 38 (3) ◽  
pp. 257-267 ◽  
Author(s):  
L. A. Sáenz-Carbonell ◽  
I. E. Maldonado-Mendoza ◽  
O. Moreno-Valenzula ◽  
R. Clau-Uitz ◽  
M. López-Meyer ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Catharanthus Roseus ◽  
Medium Ph

In vitro - studies with antler bone cells: Structure forming capacity, osteocalcin production and influence of sex steroids

2006 ◽  
Vol 15 (04) ◽  
pp. 245-257 ◽  
Author(s):  
H. J. Rolf ◽  
K. G. Wiese ◽  
H. Siggelkow ◽  
H. Schliephake ◽  
G. A. Bubernik
Keyword(s):  
Sex Steroids ◽  
Bone Cells ◽  
In Vitro Studies ◽  
Osteocalcin Production

In Vitro Studies on the Mechanism of the Antifibrino-lytic Action of E-Aminocaproic Acid (EACA)

1968 ◽  
Vol 19 (03/04) ◽  
pp. 584-592 ◽  
Author(s):  
Hanna Lukasiewicz ◽  
S Niewiarowski
Keyword(s):  
Aminocaproic Acid ◽  
Test Tube ◽  
In Vitro Studies ◽  
Lytic Action ◽  
Human Plasminogen ◽  
Experimental Findings ◽  
Fibrin Clots

Summary and Conclusion1. It has been found that EACA does not inhibit activation of human plasminogen into plasmin by SK and UK in a concentration of 5 × 10–2 M. The activation of bovine plasminogen by SK and UK is inhibited by this concentration of EACA but not by a lower one.2. EACA in concentrations of 1,5 × 10–1 – 10–4 M does not inhibit casein proteolysis by plasmin. The proteolysis of fibrinogen and fibrin measured by the release of TCA soluble tyrosine is inhibited by EACA in concentrations of 1,5 × 10–1 – 10–2 M.3. The lysis of non-stabilized clots by plasmin measured in a test tube was inhibited by an EACA concentration of 5 × 10–3 – 5 × 10–4 M. The lysis of stabilized clots by plasmin was inhibited by an EACA concentration of 10–5 M.4. On the basis of experimental findings and data given in literature the authors postulate that the mechanism of the antifibrinolytic effects of EACA consists mainly in a modification of plasmin action on fibrin. These effects are dependent on the structure of the fibrin clots.

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