The Novel Device for Irreversible Electroporation: Thermographic Comparison with Radiofrequency Ablation

2017 ◽  
pp. 72-79 ◽  
Author(s):  
Veronika Novotna ◽  
Dalibor Cervinka
Keyword(s):  
Radiofrequency Ablation ◽  
Irreversible Electroporation ◽  
The Novel ◽  
Novel Device

EFFICACY OF A NOVEL DEVICE TO DETECT, ALERT AND RESOLVE NEONATAL APNEA - PILOT STUDY

2019 ◽  
Vol 9 (9) ◽  
pp. 608-613
Author(s):  
Dr. Swapna Lingaldinna,Dr. Himabindu Singh,Mona Sharma*
Keyword(s):  
Newborn Care ◽  
Standard Of Care ◽  
The Novel ◽  
Tertiary Referral ◽  
Tertiary Referral Hospital ◽  
Care Community ◽  
Novel Device ◽  
Sick Newborn ◽  
Central Apneas ◽  
Neonatal Apnea

Objective: To measure the accuracy of a novel device in detecting Bradycardia andDesaturation (B&D) events and to determine its efficacy in resolving apneas innewborns with comparison to standard monitor (which only detects B&D eventsand alerts).Design: This was a prospective observational study.Setting: Sick Newborn Care Unit of a large tertiary referral hospital in Hyderabad,India.Methods: 31 newborns were provided with a novel device, which monitored oxygensaturation and pulse rate and alarmed when values dropped below a set thresholdwhich is referred as an event, henceforth. The novel device also provided footstimulation in response to above-mentioned events. When the monitor alarmed, anurse attended to the baby to confirm whether the baby was breathing and whetherthe event had been resolved by the device. If the event had not resolved, appropriateaction as per the standard-of-care was performed.Results: The novel device “ApneBootTM” positively detected B&D events 94.03% oftimes as compared to the standard reference monitor. 56 of 67 observed B&D eventswere visually confirmed to be apneas, indicating that 83.6% of B&D eventscoincided with apneas. Of the 56 apneic events, 50 were central apneas, of which 35were resolved by the novel device, making the device’s efficacy of apnea resolution70%.Conclusion: The results of the study indicate that this novel device “ApneBootTM”is very effective in detecting and alarming B&D events, which coincides with theapnea, and resolving it by providing foot stimulation.Keywords: Novel Device, Neonatal Apnea, Low Birth Weight, Body Temperature,Kangaroo Mother Care, Community Health,

Measuring Earwax Cortisol Concentration Using a Non-Stressful Method (Preprint)

2020 ◽  
Author(s):  
Andrés Herane-Vives
Keyword(s):  
Cortisol Level ◽  
Local Stress ◽  
Extraction Methods ◽  
Cortisol Concentration ◽  
The Novel ◽  
Sampling Device ◽  
Related Factors ◽  
Novel Device ◽  
Cortisol Levels ◽  
The Right

BACKGROUND “Short-term” samples are not the most appropriate for reflecting Chronic Cortisol Concentration (CCC). Although hair is used for reflecting the systemic cortisol level over “long-term”, its use appears clinically problematic. Local stress and non-stress related factors may release a circumscribed cortisol secretion that is accumulated in hair. Non-stressful earwax extraction methods may provide a more accurate specimen to measure CCC. OBJECTIVE Correlate cortisol levels using hair, serum and earwax samples METHODS Earwax from both ears of 37 controls were extracted using a clinical procedure commonly associated with local pain. One month later, earwax from the left ear side was extracted using the same procedure, and earwax from the right ear side was comfortably extracted, using an earwax self-sampling device. Participants also provided one centimetre of hair that represented the retrospective month of cortisol output, and one serum sample that reflected the effect of systemic stressors on cortisol levels. Earwax (ECC), Hair (HCC) and Serum (SCC) Cortisol Concentration were correlated and compared. Confounders´ effect on cortisol levels were studied. RESULTS Serum showed the largest and hair the lowest cortisol concentration (p<0.01). Left-ECC was larger than Right-ECC (p=0.03). Right-ECC was the only sample unaffected by confounders (all p>0.05). Right-ECC and HCC showed the only significant association (r=0.39; p=0.03). CONCLUSIONS The self-sampling device did not represent a local stressor for the ceruminous glands. It provided the cortisol level with the least likely to be affected by confounding factors over the previous month. ECC using the novel device may constitute another accurate, but more suitable and affordable specimen for measuring CCC.

Assessment of Various Types of US Findings after Irreversible Electroporation in Porcine Liver: Comparison with Radiofrequency Ablation

2015 ◽  
Vol 26 (2) ◽  
pp. 279-287.e3 ◽  
Author(s):  
Katsutoshi Sugimoto ◽  
Fuminori Moriyasu ◽  
Yoshiyuki Kobayashi ◽  
Kazuhiko Kasuya ◽  
Yuichi Nagakawa ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Irreversible Electroporation ◽  
Porcine Liver ◽  
Us Findings

scholarly journals PYROLYSIS OF SOLID WASTE AND ITS COMPONENTS IN A LAB SCALE INDUCTION-HEATING REACTOR

Detritus ◽  
2021 ◽  
pp. 107-112
Author(s):  
Oscar Sosa ◽  
Sylvie Valin ◽  
Sébastien Thiery ◽  
Sylvain Salvador
Keyword(s):  
Beech Wood ◽  
Fast Pyrolysis ◽  
Fluidized Bed Reactor ◽  
Thermochemical Conversion ◽  
Homogeneous Distribution ◽  
The Novel ◽  
Reaction Products ◽  
Heating Rates ◽  
Fast Heating ◽  
Novel Device

The present study investigates the thermochemical conversion of Solid Recovered Fuel (SRF), represented by selected “model materials”. A laboratory-scale induction heated device was specifically developed to achieve fast pyrolysis conditions close to those encountered in a fluidized bed reactor. The novel device can handle up to 5 grams of solid, allowing fast heating rates (near 70°C/s) and a homogeneous distribution of temperature all along the reactor. Pyrolysis tests of a SRF sample and four model materials (Polyethylene, Polyethylene Terephthalate, beech wood, cardboard) were performed at 800°C. The yield and composition of the produced gas for each sample were determined. Experimental results will help to elucidate the relation between the initial components of waste derived fuels and the obtained reaction products.

scholarly journals A Novel Earwax Method to Measure Acute and Chronic Glucose Levels

Diagnostics ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1069
Author(s):  
Andrés Herane-Vives ◽  
Susana Espinoza ◽  
Rodrigo Sandoval ◽  
Lorena Ortega ◽  
Luis Alameda ◽  
...  
Keyword(s):  
Postprandial Glucose ◽  
The Novel ◽  
Sampling Device ◽  
Clinical Method ◽  
Postprandial Glycemia ◽  
Novel Device ◽  
Glucose Levels ◽  
Standard Serum

Diabetes is the fourth cause of death globally. To date, there is not a practical, as well as an accurate sample for reflecting chronic glucose levels. We measured earwax glucose in 37 controls. Participants provided standard serum, glycated hemoglobin (HbA1c) and earwax samples at two time-points, one month apart. The specimens measured baseline fasting glucose, a follow-up postprandial glucose level and a between sample chronic glucose, calculated using the average level on the two occasions. The baseline earwax sample was obtained using a clinical method and the follow-up using a novel self-sampling earwax device. The earwax analytic time was significantly faster using the novel device, in comparison to the clinical use of the syringe. Earwax accurately reflected glucose at both assessments with stronger correlations than HbA1c. Follow-up postprandial concentrations were more significant than their respective fasting baseline concentrations, reflecting differences in fasting and postprandial glycemia and more efficient standardization at follow up. Earwax demonstrated to be more predictable than HbA1c in reflecting systemic fasting, postprandial and long-term glucose levels, and to be less influenced by confounders. Earwax glucose measurements were approximately 60% more predictable than HbA1c in reflecting glycemia over a month. The self-sampling device provided a sample that might accurately reflect chronic glycemia.

scholarly journals AngioVac System Used for Vegetation Debulking in a Patient with Tricuspid Valve Endocarditis: A Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Hossam Abubakar ◽  
Ahmed Rashed ◽  
Ahmed Subahi ◽  
Ahmed S. Yassin ◽  
Mohamed Shokr ◽  
...  
Keyword(s):  
Case Report ◽  
Tricuspid Valve ◽  
The Novel ◽  
Review Of The Literature ◽  
Novel Device ◽  
Heart Chamber ◽  
Improved Outcomes ◽  
Percutaneous Removal ◽  
Few Data ◽  
Tricuspid Valve Endocarditis

AngioVac is a vacuum-based device approved in 2014 for percutaneous removal of undesirable materials from the intravascular system. Although numerous reports exist with regard to the use of the AngioVac device in aspiration of iliocaval, pulmonary, upper extremity, and right-sided heart chamber thrombi, very few data are present demonstrating its use in treatment of right-sided endocarditis. In this case report, we describe the novel device used in debulking a large right-sided tricuspid valve vegetation reducing the occurrence of septic embolisation and enhancing the efficacy of antibiotics in clearance of bloodstream infection. Further research is needed in larger RSIE patient populations to confirm the benefits and the potential of improved outcomes associated with the AngioVac device as well as identify its potential complications.

Efficiency Optimized Pneumatic Pressure Booster

2019 ◽  
Author(s):  
Olivier Reinertz ◽  
Katharina Schmitz
Keyword(s):  
Load Distribution ◽  
State Of The Art ◽  
Analytical Description ◽  
The Novel ◽  
One Dimensional ◽  
Pneumatic Pressure ◽  
Novel Device ◽  
Working Cycle ◽  
Promising Solution ◽  
Dimensional Simulation

Abstract In the scope of this paper, a novel efficiency optimized supply pressure adaptive concept of pneumatic pressure boosters is presented. It is deduced from a profound analysis of state of the art components. The working cycle of the pump chambers can be divided into a filling, compression, pumping and decompression phase. A promising solution for efficiency improvements, which is further analyzed in the scope of this paper, is to adapt the required force of the compression chambers by nonlinear mechanics. Thus, a smaller force at the end of the stroke is required and a reduced air consumption of the driving chamber occurs. As the force demand of the compression chamber and therewith the load distribution over the stroke changes with the operational pressures, an adaptive concept needs to be implemented. The novel device and its parameterization are deduced by means of an analytical description of state of the art pressure boosters. Subsequently, it is investigated by one-dimensional simulation in DSHplus. The results show broad applicability of the method in relevant applications and huge energy saving potentials compared to state of the art products.

scholarly journals Genicular Nerve Radiofrequency Ablation for Chronic Knee Pain Using a Three-Tined Electrode: A Technical Description and Case Series

Pain Medicine ◽  
2020 ◽  
Vol 21 (12) ◽  
pp. 3344-3349
Author(s):  
Edvin Koshi ◽  
Cole W Cheney ◽  
Beau P Sperry ◽  
Aaron Conger ◽  
Zachary L McCormick
Keyword(s):  
Radiofrequency Ablation ◽  
Knee Osteoarthritis ◽  
Knee Pain ◽  
Rating Scale ◽  
Case Series ◽  
Numeric Rating Scale ◽  
Vastus Medialis ◽  
The Novel ◽  
Chronic Knee Pain ◽  
Numeric Rating

Abstract Background Genicular nerve radiofrequency ablation (RFA) for the treatment of chronic knee pain has traditionally targeted the superomedial, superolateral, and inferomedial genicular nerves. However, recent cadaveric studies of knee neuroanatomy demonstrate varied locations of these specific nerves as well as additional articular nerves. This work suggests that traditional genicular nerve RFA lesion locations may be inadequate. Objective 1) To describe a novel protocol utilizing a three-tined RFA electrode to target the superomedial (SMGN), superolateral (SLGN), and inferomedial genicular nerves (IMGN), as well as the terminal articular branches of the nerves to the vastus medialis (NVM), intermedius (NVI), and lateralis (NVL). 2) To assess the ability of this technique to reduce chronic knee pain. Methods Case series of consecutive patients with six or more months of refractory knee pain who underwent genicular nerve RFA according to the novel protocol described. Seven discrete RFA lesions were placed to target the SMGN, NVM, NVI, NVL, SLGN, and IGMN. Results Eleven patients underwent RFA, nine with knee osteoarthritis and two postarthroplasty. At one month, 91% (95% CI = 59–100%), 82% (95% CI = 48–98%), and 9% (95% CI = 2–41%), of patients reported ≥50%, ≥80%, and 100% improvement in knee pain on the numeric rating scale, respectively. These results were sustained at six months. There were no complications. Discussion/Conclusions These preliminary data suggest the feasibility and possible effectiveness of genicular nerve RFA using the described novel protocol including a three-tined electrode. Larger-scale studies with comparative groups are warranted.

Sign in / Sign up

Export Citation Format

Share Document