Use of Molecular Markers in the Conservation Management of Tropical Trees

The rarest species of relict ironwood C. caucasica Willd. is naturally occurred on the Ile-Alatau Mountains but very little is known about genetic diversity and distribution and size of its populations in Kazakhstan. In during the sampling expedition were found two additional plant populations in Dzungarian and Kyrgyz Alatau Ranges. The objective of this work was targeted towards sequencing ITS region of C. caucasica and compare the obtained nucleotide sequence with available data on NCBI GeneBank for confident species identification. The identity of C. caucasica sequence and available C. australis and C. bungeana sequences was 93.87% and less. It could be associated with absence sequences producing significant alignments with the studied ironwood sequence and important deposited sequences of GenBank lacking Latin binominals is from environmental samples. Clarifying taxonomical status species and subspecies is difficult by morphological data and molecular markers should be used to correct identifying an endangered species of C. caucasica growing in the east-southern and the south regions of Kazakhstan and providing direction to the conservation management of the plant.

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Trawling the peripheral circulation for disseminating breast cancer cells and micrometastatic lymph node deposits using 3 new molecular markers: UROC28, CLSP and BCSG1

European Journal of Cancer ◽

10.1016/s0959-8049(02)80544-5 ◽

2002 ◽

Vol 38 (11) ◽

pp. S163

Author(s):

K Gomez

Keyword(s):

Breast Cancer ◽

Molecular Markers ◽

Lymph Node ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Peripheral Circulation

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CD44-9v and CD44-10v are potential molecular markers for squamous cell carcinoma of the vulva

Journal of the Society for Gynecologic Investigation ◽

10.1016/s1071-5576(99)00045-3 ◽

2000 ◽

Vol 7 (1) ◽

pp. 70-75 ◽

Cited By ~ 3

Author(s):

L Rodríguez-Rodríguez

Keyword(s):

Squamous Cell Carcinoma ◽

Molecular Markers ◽

Cell Carcinoma ◽

Squamous Cell

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Molecular Markers for Colorectal Cancer

Swiss Surgery ◽

10.1024/1023-9332.7.6.243 ◽

2001 ◽

Vol 7 (6) ◽

pp. 243-248

Author(s):

Scheunemann ◽

Hosch ◽

Kutup ◽

Izbicki

Keyword(s):

Colorectal Cancer ◽

Molecular Markers ◽

Prospektive Studien ◽

Therapeutische Konsequenzen

Die Einführung von immunhisto-/zytochemischen und molekularbiologischen bzw. zytogenetischen Methoden in der onkologische Forschung hat trotz vieler nach wie vor bestehender offener Fragen insgesamt zu einem besseren Verständnis der genetischen Ursachen der Tumorentstehung geführt. Darüber hinaus ergaben sich in verschiedenen Studien Hinweise für eine prognostische Relevanz von bestimmten (zyto)genetischen Veränderungen bzw. residualen Tumorzellen in Lymphknoten oder Knochenmark. Bevor diese Untersuchungen jedoch in den klinischen Alltag Einzug halten und therapeutische Konsequenzen abgeleitet werden können, sind weitere prospektive Studien mit groáen Patientenfallzahlen sowie vereinheitlichte und methodologisch praktikable Untersuchungstechniken zu fordern.

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