scholarly journals Evaluation of the Lambs’ State of Consciousness Signs during Halal and Traditional Slaughtering

Agriculture ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 557
Author(s):  
Roberta Barrasso ◽  
Vincenzo Tufarelli ◽  
Edmondo Ceci ◽  
Francesco Luposella ◽  
Giancarlo Bozzo
Keyword(s):  
Electric Current ◽  
Brain Function ◽  
Traditional Method ◽  
Time Intervals ◽  
Corneal Reflex ◽  
Group A ◽  
Group B ◽  
The Brain

The aim of this study was to evaluate the persistence of two signs of consciousness (rhythmic breathing and corneal reflex) in lambs slaughtered according to the traditional method and Halal ritual rite. A total of 240 lambs were examined and divided into two equal groups (n = 120 each). Lambs of group A were subjected to the stunning phase by the action of an electric current on the brain, while lambs of group B were slaughtered according to the religious Halal method without prior stunning. Rhythmic breathing (RB) and corneal reflex (CR) were used as indicators of prolonged brain function, and their evaluation was carried out by the operators in three subsequent steps at 15 s, 30 s, and 90 s post-bleeding, respectively. The stunning of the lambs reduced the animal’s state of consciousness and, consequently, reduced suffering, pain, and distress. Indeed, the lambs of group B showed longer duration consciousness than the animals stunned by electrodes. The permanence of the reflexes in Halal slaughter could be reduced by introducing a reversible stunning method to make the animal temporarily unconscious. Moreover, given that our results revealed consciousness also after 90 s post-cut, the assessment of the animal’s state of consciousness in wider time intervals than those commonly used is recommended.

scholarly journals The Influence of Broilers’ Body Weight on the Efficiency of Electrical Stunning and Meat Quality under Field Conditions

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1362
Author(s):  
Giorgio Smaldone ◽  
Stefano Capezzuto ◽  
Rosa Luisa Ambrosio ◽  
Maria Francesca Peruzy ◽  
Raffaele Marrone ◽  
...  
Keyword(s):  
European Union ◽  
Body Weight ◽  
Meat Quality ◽  
Well Being ◽  
Electrical Equipment ◽  
Post Mortem ◽  
The European Union ◽  
Body Weights ◽  
Corneal Reflex ◽  
Experimental Trials

Water-bath stunning represents the most-applied stunning system in poultry slaughtering, but within the European Union, specific indications on electric parameters that should be used, such as voltage, are missing. The objective of this study was to evaluate the efficiency of two commercially available types of electrical equipment (A and B) on broilers with different live body weights and the influence of the tested parameters on meat quality. Experimental trials in a European Union-approved slaughterhouse were carried out using two different stunners. 6600 broilers, divided into three weight groups, were stunned applying different protocols based on the same current frequencies and intensity but different voltages. The state of unconsciousness (presence of corneal reflex and wings flapping) and post-mortem defects (pectoral hemorrhages and dark meat) were evaluated by blinded trained operators. The presence of corneal reflex and petechiae were the most reported consciousness signs and post-mortem injuries, respectively. Different weights played an important role within stunner A, registering statistical differences (p < 0.01) among groups. Considering injuries, an inverse relationship between body weight and lesions was found. The results highlighted the effectiveness of both stunning systems applying the best combination of electrical parameters considering the weight of the animal and ensuring its well-being.

Effect of Subarachnoid Bupivacaine Block on Anesthetic Requirements for Thiopental in Rats 

1998 ◽  
Vol 88 (4) ◽  
pp. 1036-1042 ◽  
Author(s):  
Sunil Eappen ◽  
Igor Kissin
Keyword(s):  
Local Anesthetic ◽  
Direct Action ◽  
Afferent Input ◽  
Crossover Design ◽  
Hemodynamic Parameters ◽  
Motor Responses ◽  
Withdrawal Reflex ◽  
Corneal Reflex ◽  
To Receive ◽  
The Brain

Background Subarachnoid bupivacaine blockade has been reported to reduce thiopental and midazolam hypnotic requirements in patients. The purpose of this study was to examine if local anesthetically induced lumbar intrathecal blockade would reduce thiopental requirements for blockade of motor responses to noxious and nonnoxious stimuli in rats. Methods After intrathecal and external jugular catheter placement, rats were assigned randomly to two groups in a crossover design study, with each rat to receive either 10 microl of 0.75% bupivacaine or 10 microl of normal saline intrathecally. The doses of intravenously administered thiopental required to ablate the eyelid reflex, to block the withdrawal reflex of a front limb digit, and to block the corneal reflex were compared. In two separate groups of animals, hemodynamic parameters and concentrations of thiopental in the brain were compared between intrathecally administered bupivacaine and saline. Results The thiopental dose required to block the described responses was decreased with intrathecally administered bupivacaine versus intrathecally administered saline from (mean +/- SD) 40 +/- 5 to 24 +/- 4 mg/kg (P &lt; 0.001) for the eyelid reflex, from 51 +/- 6 to 29 +/- 6 mg/kg (P &lt; 0.005) for front limb withdrawal, and from 67 +/- 8 to 46 +/- 8 mg/kg (P &lt; 0.01) for the corneal reflex. The concentration of thiopental in the brain at the time of corneal reflex blockade for the group given bupivacaine was significantly lower than in the group given saline (24.1 vs. 35.8 microg/g, P = 0.02). Conclusion This study demonstrates that lumbar intrathecally administered local anesthetic blockade decreases anesthetic requirements for thiopental for a spectrum of end points tested. This effect is due neither to altered pharmacokinetics nor to a direct action of the local anesthetic on the brain; rather, it is most likely due to decreased afferent input.

THE CORNEAL REFLEX IN ANAESTHESIA

BMJ ◽  
1905 ◽  
Vol 1 (2313) ◽  
pp. 971-972
Author(s):  
S. C. Legge
Keyword(s):  
Corneal Reflex

Abstract 16483: Prognostic Value of Neurological Exam in Cardiac Arrest Patients Treated With Therapeutic Hypothermia in the Absence of Withdrawal of Life-sustaining Therapy

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Elizabeth Matthews ◽  
Jessica Magid-Bernstein ◽  
Angela Velazquez ◽  
Cristina Falo ◽  
Soojin Park ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Therapeutic Hypothermia ◽  
Cause Of Death ◽  
Prognostic Value ◽  
Light Response ◽  
Pupillary Response ◽  
Columbia University ◽  
Poor Outcome ◽  
Corneal Reflex ◽  
Neurological Exam

Objectives: Withdrawal of life-sustaining therapy (WLST) is the most common cause of death following cardiac arrest (CA). A well-described “self-fulfilling prophecy” exists, in which a poor exam often prompts WLST. The prognostic value of the neurological exam at various time points, in the absence of WLST, remains unknown. Methods: All patients (N=291) treated at Columbia University with therapeutic hypothermia (TH) following CA between May 2007 and February 2015 were identified. Neurological exams were documented at admission, 72 hours, five days and seven days after arrest. Glasgow coma motor scores (GCS-motor) no better than extensor posturing, bilaterally absent pupillary light response and bilaterally absent corneal reflexes were considered poor exams. Patients were excluded if the cause of death was WLST (n=125) or they died despite full support prior to 7 days (n=70). A cerebral performance score (CPC) at hospital discharge of 3-5 was considered a bad outcome. False positive rates (FPRs) in percentages were calculated. Results: A total of 96 patients were analyzed (average age 59±17 years, 40% female, 91% with pre-hospitalization CPC 1-2, bystander CPR in 69%, initial rhythm of VT/FT in 41%, mean ROSC 19±15 minutes). Sixty-one percent of patients had a poor outcome. GCS-motor was associated with a poor outcome, with FPRs of 36.3% (21-63.6), 29.4% (15.7-47.7), 11.8% (3.8-28.4) and 10.8% (3.5-26.4) at admission, 72 hours, five days and seven days respectively. Bilaterally absent corneal reflexes had FPRs of 29.2% (13.4-51.3), 26.3% (10.1-51.4), 5.3% (0.3-28.1) and 0% (0-18.5). Bilaterally absent pupillary response had the lowest FPRs at 8.3% (2.2-23.6), 0% (0-13.3), 0% (0-14.1), and 0% (0-13.7). Conclusion: A poor neurological exam remains a significant predictor of poor outcome following cardiac arrest. In the setting of TH, the pupillary exam reaches 100% specificity at 72 hours, while the GCS-motor and corneal reflex have unacceptably high rates of good outcomes despite poor exams. They become more specific over time, suggesting that patients may benefit from delaying prognostication until at least five days after arrest.

Sumatriptan and Corneal Reflexes in Headache-Free Migraine Patients: A Randomized and Placebo-Controlled Crossover Study

Cephalalgia ◽  
2007 ◽  
Vol 27 (2) ◽  
pp. 165-172 ◽  
Author(s):  
V Busch ◽  
S Kaube ◽  
W Schulte-Mattler ◽  
H Kaube ◽  
A May
Keyword(s):  
Oral Administration ◽  
Crossover Study ◽  
Blink Reflex ◽  
Trigeminal System ◽  
Healthy Controls ◽  
Free Interval ◽  
Nociceptive Blink Reflex ◽  
Before And After ◽  
Corneal Reflex ◽  
Baseline Response

A temporary sensitization of central trigeminal neurones in migraine patients during acute attacks has been described in previous studies using the electrically evoked nociceptive blink reflex. The cornea is innervated by small myelinated A-delta and unmyelinated C-fibres only. Stimulation with air puffs activates peripheral nociceptors and allows the investigation of peripheral trigeminal nerve structures. Our objective was to investigate whether corneal reflex examinations with air puff stimulation detect abnormalities in migraineurs during their pain-free interval and if the corneal reflex may be modulated by the administration of an oral triptan. After validation of the nociceptive air puff technique by investigating the corneal reflexes before and after a local anaesthesia of the cornea, we recorded corneal reflexes in 25 migraineurs during their pain-free period and 25 healthy controls before and after the oral administration of 100 mg sumatriptan in a randomized, placebo-controlled, crossover study. Baseline response areas under the curve (AUCs) and latencies of the R2 components of the corneal reflexes did not show any significant differences between patients and controls. Patients did not show any significant differences regarding their headache and non-headache side. The use of an oral triptan had no significant influence on latencies or AUCs in both patients and controls. Our data suggest that there is no facilitation of the trigeminal system in the headache-free interval among patients with migraine. The stable corneal reflexes after the oral administration of 100 mg sumatriptan suggest that there was no inhibition of the trigeminal system, both in patients during their headache-free period and in healthy controls.

The Trigemino-Pupillary Response in Cluster Headache

Cephalalgia ◽  
1993 ◽  
Vol 13 (5) ◽  
pp. 338-342 ◽  
Author(s):  
Giuseppe Micieli ◽  
Cristina Tassorelli ◽  
Luigi Ruiz ◽  
Giorgio Sandrini ◽  
Giuseppe Nappi
Keyword(s):  
Cluster Headache ◽  
Pain Perception ◽  
Active Phase ◽  
Pupillary Response ◽  
Neural Systems ◽  
Episodic Cluster Headache ◽  
Corneal Reflex ◽  
Remission Phase ◽  
Electrical Stimuli ◽  
Trigeminal Reflex

Central impairment of the integrative neural systems controlling vegetative function and pain perception has been demonstrated in cluster headache (CH). Recently, we described the human pupillary response (trigeminal reflex) to quantified (painless and painful) corneal stimulation with a combined neurophysiological and pharmacological technique. In this study, the trigeminal reflex was evaluated in 26 subjects with episodic cluster headache. During the active phase of the disease, on the side of the pain we observed reduced mydriasis to electrical stimuli with an intensity equal to the corneal reflex threshold, and on both sides to stimuli with intensity that equalled the pain threshold. No difference was found when amplitude of the miotic phase was compared in the different groups. These suggest disordered pupillary activation in response to pain, probably sympathetic in origin, which is bilateral, detectable also during the remission phase and which cannot be explained simply by the antidromic release of pain-related peptides.

Hypothalamic stimulation for trigeminal neuralgia in multiple sclerosis patients: efficacy on the paroxysmal ophthalmic pain

2009 ◽  
Vol 15 (11) ◽  
pp. 1322-1328 ◽  
Author(s):  
R. Cordella ◽  
A. Franzini ◽  
L. La Mantia ◽  
C. Marras ◽  
A. Erbetta ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Deep Brain Stimulation ◽  
Trigeminal Neuralgia ◽  
Posterior Hypothalamus ◽  
Corneal Reflex ◽  
Multiple Sclerosis Patients ◽  
Ablative Procedures ◽  
Paroxysmal Pain ◽  
Deep Brain

Trigeminal neuralgia is a disorder characterized by paroxysmal pain arising in one or more trigeminal branches; it is commonly reported in multiple sclerosis. In multiple sclerosis patients the ophthalmic branch may be frequently involved and the risks carried by neurosurgical ablative procedures are higher including major adverse effects such as corneal reflex impairment and keratitis. The objective of this works is to assess the role of posterior hypothalamus neuromodulation in the treatment of trigeminal neuralgia in multiple sclerosis patients. Five multiple sclerosis patients suffering from refractory recurrent trigeminal neuralgia involving all three trigeminal branches underwent deep brain stimulation of the posterior hypothalamus. The rationale of this intervention emerges from our earlier success in treating pain patients suffering from trigeminal autonomic cephalalgias. After follow-up periods that ranged from 1 to 4 years after treatment, the paroxysmal pain arising from the first trigeminal branch was controlled, whereas the recurrence of pain in the second and third trigeminal branches necessitated repeated thermorhizotomies to control in pain in two patients after 2 years of follow-up. In conclusion, deep brain stimulation may be considered as an adjunctive procedure for treating refractory paroxysmal pain within the first trigeminal division so as to avoid the complication of corneal reflex impairment that is known to follow ablative procedures.

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