Motion Compensated Magnetic Resonance Reconstruction Using Inverse-Consistent Deformable Registration: Application to Real-Time Cine Imaging

Abstract Background Coronavirus disease 2019 (COVID-19) induces myocardial injury, either direct myocarditis or indirect injury due to systemic inflammatory response. Myocardial involvement has been proved to be one of the primary manifestations of COVID-19 infection, according to laboratory test, autopsy, and cardiovascular magnetic resonance (CMR). However, the middle-term outcome of cardiac involvement after the patients were discharged from the hospital is yet unknown. The present study aimed to evaluate mid-term cardiac sequelae in recovered COVID-19 patients by CMR Methods A total of 47 recovered COVID-19 patients were prospectively recruited and underwent CMR examination. The CMR protocol consisted of black blood fat-suppressed T2 weighted imaging, T2 star mapping, left ventricle (LV) cine imaging, pre- and post-contrast T1 mapping, and late gadolinium enhancement (LGE). LGE were assessed in mixed both recovered COVID-19 patients and healthy controls. The LV and right ventricle (RV) function and LV mass were assessed and compared with healthy controls. Results A total of 44 recovered COVID-19 patients and 31 healthy controls were studied. LGE was found in 13 (30%) of COVID-19 patients. All LGE lesions were located in the mid myocardium and/or sub-epicardium with a scattered distribution. Further analysis showed that LGE-positive patients had significantly decreased LV peak global circumferential strain (GCS), RV peak GCS, RV peak global longitudinal strain (GLS) as compared to non-LGE patients (p < 0.05), while no difference was found between the non-LGE patients and healthy controls. Conclusion Myocardium injury existed in 30% of COVID-19 patients. These patients have depressed LV GCS and peak RV strains at the 3-month follow-up. CMR can monitor the COVID-19-induced myocarditis progression, and CMR strain analysis is a sensitive tool to evaluate the recovery of LV and RV dysfunction.

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Fusion imaging in brain structure measurements on a fetus phantom, combining real‐time ultrasound with magnetic resonance imaging

Australasian Journal of Ultrasound in Medicine ◽

10.1002/ajum.12246 ◽

2021 ◽

Author(s):

Anastasija Arechvo ◽

Göran Lingman ◽

Lars Thurn ◽

Tomas Jansson ◽

Ligita Jokubkiene

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Real Time ◽

Brain Structure ◽

Fusion Imaging ◽

Resonance Imaging

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Nanometre-Scale Visualization of Chemical Parameter Changes by T1-Weighted ODMR Imaging Using a Fluorescent Nanodiamond

Chemosensors ◽

10.3390/chemosensors8030068 ◽

2020 ◽

Vol 8 (3) ◽

pp. 68

Author(s):

Takahiro Fujisaku ◽

Ryuji Igarashi ◽

Masahiro Shirakawa

Keyword(s):

Magnetic Resonance ◽

Laser Pulse ◽

Real Time ◽

Physical Parameters ◽

Biological Processes ◽

Chemical Parameter ◽

Ph Conditions ◽

Optically Detected ◽

Life Phenomena ◽

Selection Of

The dynamics of physical parameters in cells is strongly related to life phenomena; thus, a method to monitor and visualize them on a single-organelle scale would be useful to reveal unknown biological processes. We demonstrate real-time nanometre-scale T1-weighted imaging using a fluorescent nanodiamond. We explored optically detected magnetic resonance (ODMR) contrast at various values of interval laser pulse (τ), showing that sufficient contrast is obtained by appropriate selection of τ. By this method, we visualized nanometre-scale pH changes using a functionalized nanodiamond whose T1 has a dependence on pH conditions.

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