Respiratory Syncytial Virus Mechanisms to Interfere with Type 1 Interferons

Author(s):  
Sailen Barik
1976 ◽  
Vol 4 (4) ◽  
pp. 322-325
Author(s):  
D Bardell

Infectious adenovirus type 5 and coxsackievirus type B5, both nonlipid-containing viruses, were isolated from cells fixed in acetone at 22 degrees C for 15 min, from acetone used for fixation, from the solution used for washing slides during the fluorescent antibody procedure, and after complete processing of antigen preparations with serial twofold dilutions of human antisera and fluorescein-labeled goat anti-human immunoglobulin G. Lipid-containing herpes simplex virus type 1 and respiratory syncytial virus were inactivated by acetone, and infectious virus could not be recovered at any stage in the fluorescent antibody test. Fixation in acetone at 56 degrees C destroyed the infectivity of adenovirus 5 and coxsackievirus B5 within 30 min, but no adverse effect on the antigenic determinants of either virus occurred until after 60 min, thus demonstrating that these antigens can be utilized without the hazard of infectious virus.


2011 ◽  
Vol 32 (1) ◽  
pp. 295 ◽  
Author(s):  
Ingrid Bortolin Affonso ◽  
Sandra Possebon Gatti ◽  
Bruna Alexandrino ◽  
Mônica Costa Oliveira ◽  
Andréa Souza Ramos de Medeiros ◽  
...  

1972 ◽  
Vol 70 (3) ◽  
pp. 523-529 ◽  
Author(s):  
Roy Jennings

SUMMARYSurveys for respiratory virus antibodies in the Jamaican population have shown that adenovirus, respiratory syncytial virus and parainfluenza types 1 and 3 virus antibodies are acquired early in life. The incidence of haemagglutination-inhibiting antibodies to parainfluonza viruses increases rapidly with age and almost all adults possess parainfluenza type 3 antibody, usually in high titre. Parainfluenza type 1 antibodies are only slightly less common. Complement-fixing antibodies to the adenovirus group were also observed to increase in incidence with age.Complement-fixing antibody to respiratory syncytial virus was less common in Jamaican sera than antibody to the other respiratory viruses described here. The highest titres were observed in the youngest age-group.


2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Krist Helen Antunes ◽  
José Luís Fachi ◽  
Rosemeire de Paula ◽  
Emanuelle Fraga da Silva ◽  
Laís Passariello Pral ◽  
...  

2003 ◽  
Vol 92 (2) ◽  
pp. 151-156 ◽  
Author(s):  
Rachel Cameron ◽  
Charles Buck ◽  
Denise Merrill ◽  
Angela Luttick

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