Dynamic Radioisotope Study of the Internal Carotid Region of the Neck in Cerebrovascular Disease

1978 ◽  
pp. 171-172
Author(s):  
T. Kryst-Widźgowska ◽  
P. Kozłowski ◽  
J. Zajgner ◽  
S. Rudnicki
Keyword(s):  
Cerebrovascular Disease ◽  
Internal Carotid

Circulatory Reflexes in Cerebral Ischaemia Involving Different Vascular Territories

1970 ◽  
Vol 38 (4) ◽  
pp. 491-502 ◽  
Author(s):  
M. Gross
Keyword(s):  
Statistical Analysis ◽  
Arterial Pressure ◽  
Cerebrovascular Disease ◽  
Internal Carotid ◽  
Transient Ischaemic Attacks ◽  
Vasoconstrictor Response ◽  
Ischaemic Cerebrovascular Disease ◽  
Significant Difference ◽  
Valsalva's Manoeuvre ◽  
Circulatory Reflexes

1. Circulatory reflex function was assessed in a series of subjects with chronic ischaemic cerebrovascular disease and compared with a group of subjects with no known cerebrovascular disease by intra-arterial pressure responses to Valsalva's manoeuvre. 2. Circulatory reflexes were impaired in the patients with cerebrovascular disease as compared with controls, but statistical analysis indicated that age was a more important factor than chronic cerebrovascular disease in producing the deterioration. 3. No significant difference was found in the circulatory reflex function of subjects with ischaemia in the internal carotid territory when compared with those having ischaemia in the vertebrobasilar territory. 4. Combined ischaemia in both carotid and vertebrobasilar territories significantly impaired the cardioaccelerator but not the vasoconstrictor response to Valsalva's manoeuvre. 5. No significant difference was found in circulatory reflex function in subjects who had suffered cerebral infarction as opposed to transient ischaemic attacks.

scholarly journals Supergiant Cavernous Carotid Aneurysm: Successful Management with Ligation of Internal Carotid Artery and STA–MCA Bypass

2019 ◽  
Vol 10 (04) ◽  
pp. 697-699
Author(s):  
Navneet Singla ◽  
Ashish Aggarwal ◽  
Kokkula Praneeth ◽  
Chirag Ahuja
Keyword(s):  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Cerebrovascular Disease ◽  
Effective Treatment ◽  
Cerebral Aneurysm ◽  
Treatment Option ◽  
Internal Carotid ◽  
Successful Management ◽  
Effective Treatment Option ◽  
Cavernous Carotid Aneurysm

AbstractSupergiant cerebral aneurysm (size > 6 cm) is a rare and challenging cerebrovascular disease with few documented cases in literature. We describe a simple, safe, and effective treatment option for supergiant cavernous carotid aneurysm and discuss the proposed mechanisms for a favorable outcome.

scholarly journals Patients Receiving Extracranial to Intracranial Bypass for Atherosclerotic Vessel Occlusion Today Differ Significantly From the COSS Population

Stroke ◽  
2021 ◽  
Vol 52 (10) ◽  
Author(s):  
Lars Wessels ◽  
Nils Hecht ◽  
Peter Vajkoczy
Keyword(s):  
Cerebrovascular Disease ◽  
Internal Carotid ◽  
Artery Bypass ◽  
Superficial Temporal Artery ◽  
Temporal Artery ◽  
Artery Occlusion ◽  
Carotid Artery Occlusion ◽  
Multivessel Disease ◽  
Vessel Occlusion ◽  
Ischemic Attack

Background and Purpose: Despite the findings reported in the COSS (Carotid Occlusion Surgery Study), patients with atherosclerotic cerebrovascular disease continue to be referred for superficial temporal artery to middle cerebral artery bypass surgery. Here, we determined how today’s patients differ from the population reported in COSS. Methods: We retrospectively analyzed all patients that were referred to our Department for superficial temporal artery to middle cerebral artery bypass surgery of atherosclerotic cerebrovascular disease following the publication of COSS. Results: Between 2012 and 2019, 179 patients were referred for 186 bypass surgeries. Ninety-one (51%) patients suffered atherosclerotic, unilateral internal carotid occlusion and 88 (49%) atherosclerotic multivessel disease. All patients had received intensive medical management. A single transitory ischemic attack or ischemic stroke within the last 120 days according to the inclusion criteria of COSS occurred in only 36 out of 179 (20%) patients, whereas 27 out of 179 (15%) suffered >1 transitory ischemic attack within 120 days, 109 out of 179 (61%) had recurrent minor ischemic stroke, and 7 out of 179 (4%) were hemodynamically unstable and required blood pressure maintenance. The distribution of symptoms did not differ between atherosclerotic unilateral internal carotid artery occlusion and atherosclerotic multivessel disease ( P =0.376) but hemodynamic impairment was significantly greater in atherosclerotic multivessel disease ( P <0.001 for atherosclerotic multivessel disease versus atherosclerotic unilateral internal carotid artery occlusion). The overall perioperative stroke rate was 4.3%. Conclusions: Patients referred for flow augmentation surgery today appear to suffer more severe symptoms and vessel occlusion patterns than patients reported in COSS. A new, carefully designed randomized controlled trial appears warranted, considering the still poor prognosis of severe atherosclerotic cerebrovascular disease.

scholarly journals Simultaneous PET-MRI imaging of cerebral blood flow and glucose metabolism in the symptomatic unilateral internal carotid artery/middle cerebral artery steno-occlusive disease

2019 ◽  
Vol 47 (7) ◽  
pp. 1668-1677 ◽  
Author(s):  
Bixiao Cui ◽  
Tianhao Zhang ◽  
Yan Ma ◽  
Zhongwei Chen ◽  
Jie Ma ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Glucose Metabolism ◽  
Cerebrovascular Disease ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Bypass Surgery ◽  
Internal Carotid ◽  
Ischaemic Cerebrovascular Disease ◽  
Before And After

Abstract Purpose Cerebral blood flow (CBF) and glucose metabolism are important and significant factors in ischaemic cerebrovascular disease. The objective of this study was to use quantitative hybrid PET/MR to evaluate the effects of surgery treatment on the symptomatic unilateral internal carotid artery/middle cerebral artery steno-occlusive disease. Methods Fifteen patients diagnosed with ischaemic cerebrovascular disease were evaluated using a hybrid TOF PET/MR system (Signa, GE Healthcare). The CBF value measured by arterial spin labelling (ASL) and the standardized uptake value ratio (SUVR) measured by 18F-FDG PET were obtained, except for the infarct area and its contralateral side, before and after bypass surgery. The asymmetry index (AI) was calculated from the CBF and SUVR of the ipsilateral and contralateral cerebral hemispheres, respectively. The ΔCBF and ΔSUVR were calculated as the percent changes of CBF and SUVR between before and after surgery, and paired t tests were used to determine whether a significant change occurred. Spearman’s rank correlation was also used to compare CBF with glucose metabolism in the same region. Results The analysis primarily revealed that after bypass surgery, a statistically significant increase occurred in the CBF on the affected side (P < 0.01). The postprocedural SUVR was not significantly higher than the preprocedural SUVR (P > 0.05). However, the postprocedural AI values for CBF and SUVR were significantly lower after surgery than before surgery (P < 0.01). A significant correlation was found between the AI values for preoperative CBF and SUVR on the ipsilateral hemisphere (P < 0.01). Conclusions The present study demonstrates that a combination of ASL and 18F-FDG PET could be used to simultaneously analyse changes in patients’ cerebral haemodynamic patterns and metabolism between before and after superficial temporal artery-middle cerebral artery (STA-MCA) bypass surgery. This therefore represents an essential tool for the evaluation of critical haemodynamic and metabolic status in patients with symptomatic unilateral ischaemic cerebrovascular disease.

scholarly journals Moyamoya Syndrome in a Child with HbEβ-Thalassemia

2021 ◽  
Author(s):  
Akmal Zahra ◽  
Hanan Al-Abboh ◽  
Yousif Habeeb ◽  
Adekunle Adekile
Keyword(s):  
Cerebrovascular Disease ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Circle Of Willis ◽  
Moyamoya Syndrome ◽  
Complete Occlusion ◽  
Internal Carotid Arteries

Moyamoya is a progressive cerebrovascular disease associated with stenosis or occlusion of the arteries of the Circle of Willis. It is uncommon in thalassemia. We present a 9-year-old girl, with HbEβ-thalassemia, who presented with headache, vomiting and episodes of transient hemiparesis with complete occlusion internal carotid arteries.

Internal carotid artery haemodynamics in women with polycystic ovaries

2000 ◽  
Vol 98 (6) ◽  
pp. 661-665 ◽  
Author(s):  
K. LAKHANI ◽  
N. CONSTANTINOVICI ◽  
W. M. PURCELL ◽  
R. FERNANDO ◽  
P. HARDIMAN
Keyword(s):  
Insulin Resistance ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Cerebrovascular Disease ◽  
Cerebral Circulation ◽  
Pulsatility Index ◽  
Internal Carotid ◽  
Back Pressure ◽  
Central Feature ◽  
Polycystic Ovaries

Although polycystic ovarian syndrome (PCOS) is associated with risk factors for cerebrovascular disease, the available evidence does not demonstrate increased stroke mortality, and it has been suggested that some protective mechanisms must be operating in these women. Haemodynamic changes have been demonstrated in the pelvic vessels and aorta in this syndrome, but there have been no studies of the cerebral circulation. Since insulin resistance is a central feature of PCOS, it is of interest that cerebral blood flow may be altered in diabetic subjects. The present study was designed to assess internal carotid artery haemodynamics in women with PCOS, asymptomatic women with polycystic ovaries (PCO women) and healthy controls. Mean internal carotid pulsatility index, measured using pulsed Doppler ultrasound under standardized conditions, was significantly lower in 35 PCOS and 15 PCO women than in the 18 controls. This was also shown on multiple regression analyses. Peak systolic velocity did not differ between groups. In view of the difficulty of interpreting pulsatility index in low-impedance vascular beds, the ‘back’ pressure was calculated and found to be lower in women with polycystic ovaries. This is the first demonstration of lower pulsatility index and back pressure (suggestive of reduced vascular tone) in the cerebral circulation of these women, independent of blood pressure, insulin resistance and other endocrine or metabolic factors. Changes in internal carotid haemodynamics may offset the risk of cerebrovascular disease commonly associated with polycystic ovaries.

Dynamic radioisotope study of the internal carotid region of the neck in cerebrovascular disease

1978 ◽  
Vol 16 (1) ◽  
pp. 171-172
Author(s):  
T. Kryst-Widźgowska ◽  
P. Kozŀowski ◽  
J. Zajgner ◽  
S. Rudnicki
Keyword(s):  
Cerebrovascular Disease ◽  
Internal Carotid

scholarly journals Diverse clinical presentations of Moyamoya disease: a case series

2021 ◽  
Author(s):  
Hendrick Henrique Fernandes Gramasco ◽  
Mateus Felipe dos Santos ◽  
Yasmim Nadime José Frigo ◽  
Guilherme Drumond Jardini Anastácio ◽  
Stella de Angelis Trivellato ◽  
...  
Keyword(s):  
Cerebrovascular Disease ◽  
Moyamoya Disease ◽  
Internal Carotid ◽  
Clinical Presentation ◽  
Clinical Manifestations ◽  
Case Series ◽  
Point Of View ◽  
Cerebrovascular Events ◽  
Clinical Presentations ◽  
Proximal Occlusion

Context: Moyamoya disease or chronic occlusive cerebrovascular disease is characterized by proximal occlusion of the internal carotid artery and its branches bilaterally, generating an angiographic “smoke” pattern (moyamoya, from Japanese “something hazy”) and by diverse ischemic manifestations. Case report: The sample consists of three female patients, aged between 13 and 46 years, followed in our service due to the diagnosis of Moyamoya Disease. Among the clinical manifestations presented, ischemic cerebrovascular events with neurological deficit predominated, and one of the patients presented two episodes compatible with stroke and one episode compatible with transient ischemic accident. The youngest patient presented with a choreic picture initially interpreted as Sydenham’s chorea. Although the gold standard for the diagnosis of chronic occlusive cerebrovascular disease is cerebral arterial angiography, it was possible to observe a pattern compatible with the disease in other modalities of examination, such as cerebral arterial angiotomography and cerebral arterial angioresonance. From the therapeutic point of view, one of the patients underwent surgical intervention (encephaloduromyosinangiosis), with improvement of symptoms after treatment. Conclusions: In this paper, we emphasize the importance of complementary imaging tests in the evaluation of patients with cerebrovascular syndromes and the diversity of clinical presentation of Moyamoya disease.

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