Molecular Information Processing in the Central Nervous System

Author(s):  
Michael Conrad
Author(s):  
Mitsuo Tonoike

Though olfaction is one of the necessary senses and indispensable for the maintenance of the life of the animal, the mechanism of olfaction had not yet been understood well compared with other sensory systems such as vision and audition. However, recently, the most basic principle of “signal transduction on the reception and transmission for the odor” has been clarified. Therefore, the important next problem is how the information of odors about is processed in the Central Nervous System (CNS) and how odor is perceived in the human brain. In this chapter, the basic olfactory systems in animal and human are described and examples such as “olfactory acuity, threshold, adaptation, and olfactory disorders” are discussed. The mechanism of olfactory information processing is described under the results obtained by using a few new non-invasive measuring methods. In addition, from a few recent studies, it is shown that olfactory neurophysiological information is passing through some deep central regions of the brain before finally being processed in the orbito-frontal areas.


Author(s):  
Keita Kamijo ◽  
Yoshiaki Nishihira ◽  
Arihiro Hatta ◽  
Takeshi Kaneda ◽  
Toshiaki Wasaka ◽  
...  

Cells ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 296
Author(s):  
Sun-Nyoung Hwang ◽  
Jae Seung Lee ◽  
Kain Seo ◽  
Hyosang Lee

Astrocytes, characterized by a satellite-like morphology, are the most abundant type of glia in the central nervous system. Their main functions have been thought to be limited to providing homeostatic support for neurons, but recent studies have revealed that astrocytes actually actively interact with local neural circuits and play a crucial role in information processing and generating physiological and behavioral responses. Here, we review the emerging roles of astrocytes in many brain regions, particularly by focusing on intracellular changes in astrocytes and their interactions with neurons at the molecular and neural circuit levels.


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