Coronary Artery Diameter Z Score Calculator

2016 ◽  
pp. 321-333
Author(s):  
Shigeto Fuse
Keyword(s):  
Coronary Artery ◽  
Z Score ◽  
Coronary Artery Diameter

scholarly journals Z-score is a possible predictor of the risk of coronary artery lesion development in patients with Kawasaki disease in Japan

2021 ◽  
Author(s):  
Takayuki Suzuki ◽  
Nobuyuki Kakimoto ◽  
Tomoya Tsuchihashi ◽  
Tomohiro Suenaga ◽  
Takashi Takeuchi ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Kawasaki Disease ◽  
Coronary Artery Lesion ◽  
Z Score ◽  
Lesion Development

Coronary artery z score values in adolescent elite male soccer players

2020 ◽  
pp. 1-5
Author(s):  
Stephan Gerling ◽  
Tobias Pollinger ◽  
Markus Johann Dechant ◽  
Michael Melter ◽  
Werner Krutsch ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Arteries ◽  
High Intensity ◽  
Left Main Coronary Artery ◽  
Left Ventricular ◽  
Soccer Players ◽  
Z Score ◽  
Left Main ◽  
Luminal Diameter ◽  
The Mean

Abstract Background: With the increased training loads at very early ages in European elite youth soccer, there is an interest to analyse coronary artery remodelling due to high-intensity exercise. Design and methods: Prospective echocardiographic study in 259 adolescent elite male soccer players and 48 matched controls. Results: The mean age was 12.7 ± 0.63 years in soccer players and 12.6 ± 0.7 years in controls (p > 0.05). Soccer players had significant greater indexed left ventricular mass (93 ± 13 g/m2 versus 79 ± 12 g/m2, p = 0.001). Both coronary arteries origin could be identified in every participant. In soccer players, the mean diameter of the left main coronary artery was 3.67 mm (SD ± 0.59) and 2.61 mm (SD ± 0.48) for right main coronary artery. Controls showed smaller mean luminal diameter (left main coronary artery, p = 0.01; right main coronary artery, p = 0.025). In soccer players, a total of 91% (n = 196) and in controls a total of 94% (n = 45) showed left main coronary artery z scores within the normal range: −2.0 to 2.0. In right main coronary artery, a pattern of z score values distribution was comparable (soccer players 94%, n = 202 vs. controls 84%, n = 40). A subgroup of soccer players had supernormal z score values (>2.0 to 2.5) for left main coronary artery (9%, n = 19, p = 0.01) and right main coronary artery (6%, n = 10, p = 0.025), respectively. Conclusion: Elite soccer training in early adolescence may be a stimulus strong enough to develop increased coronary arteries diameters. In soccer players, a coronary artery z score >2.0–2.5 might reflect a physiologic response induced by multiannual high-intensity training.

Abstract O.53: Occult Coronary Artery Dilatation: An Unrecognized Category Of Coronary Involvement

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Soha Rached-d'Astous ◽  
Nour Rached-d'Astous ◽  
Frederic Dallaire ◽  
Nagib Dahdah
Keyword(s):  
Coronary Artery ◽  
Linear Equations ◽  
Young Patients ◽  
Treatment Resistance ◽  
Trend Test ◽  
Ivig Treatment ◽  
Z Score ◽  
Inflammatory Parameters ◽  
Coronary Artery Dilatation ◽  
Significant Difference

Background: The current definition of Coronary artery dilatation (CAD), Z-score >2.5, in KD may omit patients at higher risk of later complications. We propose a category of occult CAD with a Z-score variation ≥ 2 for the same CA on 2 different echocardiograms, but absolute Z-score < 2.5. We compared this new category with cases of CAD and normal CA. >Method: A retrospective review included 337 patients diagnosed with KD in our institution. Echographic data were retrieved for the fist year following diagnosis. Patients were classified in three categories: definite CA dilatation (dCAD) with Z-score ≥ 2.5, occult CA dilatation (oCAD) and normal CA (nCA). We compared inflammatory profile, IVIG treatment resistance, and timing of CA involvement. Results: There were 26.3% patients with nCA, 32.2% with oCAD and 41.1% with dCAD.Patients with KD incomplete diagnostic criteria represented 35%, 14% and 17% for NCAD, OCAD and DCAD groups respectively (p=0.008). Median time for CAD was 7 and 9.5 days for dCAD and oCAD respectively (p=0.2). A Jonckheere trend test identified a progression of inflammatory parameters through the three groups for Platelet count (p< 0.001), Albumin (p = 0.007), ESR (p = 0.04), but not for CRP (p = 0.76) and WBC (p = 0.16). There was a significant difference in treatment resistance, with 5%, 19% and 31% for NCAD, OCAD and DCAD respectively (p=0,002). Conclusion: OCAD group appears like a distinctive subgroup of KD patients showing intermediate inflammatory profiles and treatment respond in the NCAD to DCAD spectrum. Recent Z-score equations, more accurate for young patients’ CA size than former linear equations, may explain the high incidence of dCAD in this report. Further studies are needed to define the profile and propensity to complications of this subpopulation.

Abstract 221: Use of Statins in Patients with Coronary Artery Aneurysms: A Pilot Study from the North American Kawasaki Disease Registry

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Michael Khoury ◽  
Michael A Portman ◽  
Cedric Manlhiot ◽  
Anne Fournier ◽  
Rejane F Dillenburg ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Pilot Study ◽  
Kawasaki Disease ◽  
Linear Regression ◽  
North American ◽  
Z Score ◽  
Disease Registry ◽  
Coronary Artery Aneurysms ◽  
The North ◽  
Significant Difference

Background: Statins have been considered as therapy for children with coronary artery aneurysms (CAA) after Kawasaki disease (KD), due to potential beneficial pleiotropic effects which might influence chronic vascular processes and inflammation. Methods: The North American Kawasaki Disease Registry was queried to identify patients who have received statins in the first 6 months following the convalescent phase of KD. Each identified patient was matched by age, gender and CAA z score to 3 patients who were statin-naïve (controls). Linear regression models adjusted for repeated measures and maximum coronary involvement were used to determine an association of statin use with longitudinal changes in coronary artery diameter z-score. Kaplan-Meier analysis was used to compare freedom from angiographically-confirmed stenosis or interventions. Results: Of 29 patients with KD and CAA (maximum coronary artery z-score >10) who received statins at any time (of n=621, 5%), 10 (9 males) patients were started within 6 months of the acute KD episode. The mean age at KD was 6.3±3.4 years (5.4±3.5 for controls, p=0.57). Mean maximum CAA z-score was 36±14 (vs. 29±16, p=0.20); 90% of statin patients and 87% of matched controls had CAAs in 3 or more branches. Linear regression analysis of 442 serial echocardiograms showed that maximum CAA z-score decreased by -1.5 (95%CI: -2.7; -0.4) SD/year (p=0.008) for control patients compared to -2.9 (95%CI: -4.4; -1.4) SD/year (p<0.001) for statin treated patients. The difference between the rate of change of CAA z-score for statin vs. control patients did not reach statistical significance (controls vs. statins: +1.4 SD/year, 95%CI: -0.6; +3.4, p=0.18). n=7 patients (3 on statin, 4 controls) developed stenosis or had revascularization, with no significant difference between groups (HR for statin group: 2.2 (0.4-11.4), p=0.41). Conclusions: This underpowered pilot study suggests that equipoise likely exists with regards to statin therapy in children with KD and CAA, and that a formal registry-nested trial might be considered.

Abstract 28: African American Race is Not Protective Against Coronary Artery Involvement in Kawasaki Disease

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Emily P Williams ◽  
Michael S Kelleman ◽  
William T Mahle
Keyword(s):  
African American ◽  
Coronary Artery ◽  
Kawasaki Disease ◽  
Reference Group ◽  
Artery Aneurysm ◽  
Z Score ◽  
Strict Adherence ◽  
Hispanic Patients ◽  
American Children ◽  
African American Race

It has been previously reported that African American race may be protective against coronary artery aneurysm development in Kawasaki Disease (KD). We aimed to test this with our own cohort of KD patients from a large pediatric cardiology practice. Data from 250 subjects diagnosed with KD and followed as outpatients with surveillance echocardiography over a two-year period were analyzed. Twelve patients were excluded due to incomplete records or an unconfirmed diagnosis. Race designated by parent was recorded. Charts were reviewed for any coronary involvement (ectasia or aneurysm) and coronary Z-score greater than 2.5 at the time of diagnosis and at subsequent follow-up visits. Odds rations were calculated comparing each racial group to others for any coronary involvement and for coronary Z-score > 2.5. Of 238 included patients, 44.5% were African American, 37.4% were non-Hispanic white, 10.5% were Hispanic, and 7.6% identified with other racial designations. Approximately 21.9% of African American patients had any coronary involvement and 9.5% had a coronary Z-score > 2.5. Approximately 21.4% of non-Hispanic whites had any coronary involvement and 13.5% of non-Hispanic whites had a coronary Z-score > 2.5. Twenty-eight percent of Hispanic patients had any coronary involvement and 12% had a coronary Z-score > 2.5%. Of patients that identified with other racial designations, 38.9% had coronary involvement and 22.2% had a coronary Z-score > 2.5. No statistically significant odds ratios were identified. Relative to reference group (non-Hispanic whites) African American patients had nearly identical rates of 1) any coronary involvement, or 2) coronary Z-score > 2.5. KD occurs commonly in African-American children. Given equal risk for late coronary sequelae vigilance and strict adherence to consensus guidelines is essential.

scholarly journals Effect of H1receptor stimulation on coronary artery diameter in patients with variant angina: Comparison with effect of acetylcholine

1991 ◽  
Vol 17 (2) ◽  
pp. 338-345 ◽  
Author(s):  
Ken Okumura ◽  
Hirofumi Yasue ◽  
Koshi Matsuyama ◽  
Kozaburo Matsuyama ◽  
Yasuhiro Morikami ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Variant Angina ◽  
Coronary Artery Diameter

Effect of arteriolar dilation on coronary artery diameter distal to coronary stenoses

1985 ◽  
Vol 249 (5) ◽  
pp. H981-H988 ◽  
Author(s):  
J. S. Schwartz ◽  
R. J. Bache
Keyword(s):  
Regression Analysis ◽  
Coronary Artery ◽  
Coronary Occlusion ◽  
Circumflex Coronary Artery ◽  
Intracoronary Injection ◽  
Open Chest ◽  
Close Relationship ◽  
Coronary Artery Diameter ◽  
Coronary Stenoses ◽  
Chronically Instrumented Dogs

Previous studies have suggested that worsening hemodynamic severity of coronary stenoses in response to distal arteriolar dilation may be related to dilation of the normal epicardial artery adjacent to the stenosis resulting in increasing percent stenosis. To test this hypothesis we used sonomicrometry to continuously measure external circumflex coronary artery diameter distal to snare stenoses of varying severity in 19 open-chest dogs and 5 awake, chronically instrumented dogs. Arteriolar dilation produced by release of a transient coronary occlusion or by intracoronary injection of adenosine caused a decrease in circumflex coronary diameter distal to the stenosis. Regression analysis showed that circumflex diameter and pressure distal to the stenosis were directly related (mean r: transient occlusion, 0.86 +/- 0.04; adenosine, 0.97 +/- 0.01). The close relationship between pressure and diameter suggests that the decrease in diameter in response to arteriolar dilation was a passive effect. Passive coronary narrowing distal to a stenosis suggests that a similar effect may occur within a compliant stenosis, thus partly explaining the increase in severity of compliant stenoses in response to arteriolar dilation.

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