Increased 8-Hydroxyguanine Repair Activity in Animal Livers and Human Leukocytes Induced by Oxidative Stress: Effects of Diet, Physical Exercise, and Cigarette Smoking

Author(s):  
Hiroshi Kasai ◽  
Shinya Asami ◽  
Raizo Yamaguchi ◽  
Takeshi Hirano
2012 ◽  
Vol 53 ◽  
pp. S197
Author(s):  
A.T.S. Wyse⁎ ◽  
M.J. Da Cunha ◽  
A.A. Da Cunha ◽  
A.G.K. Ferreira ◽  
F.R. Machado ◽  
...  

Redox Biology ◽  
2018 ◽  
Vol 17 ◽  
pp. 315-322 ◽  
Author(s):  
Agnès Martin ◽  
Camille Faes ◽  
Tadej Debevec ◽  
Chantal Rytz ◽  
Grégoire Millet ◽  
...  

2012 ◽  
Vol 30 (2) ◽  
pp. 69-74 ◽  
Author(s):  
Maira J. Cunha ◽  
Aline A. Cunha ◽  
Andréa G.K. Ferreira ◽  
Fernanda R. Machado ◽  
Felipe Schmitz ◽  
...  

2020 ◽  
Vol 19 (5) ◽  
pp. 336
Author(s):  
Luiza Minato Sagrillo ◽  
Viviane Nogueira De Zorzi ◽  
Luiz Fernando Freire Royes ◽  
Michele Rechia Fighera ◽  
Beatriz Da Silva Rosa Bonadiman ◽  
...  

Physical exercise has been shown to be an important modulator of the antioxidant system and neuroprotective in several diseases and treatments that affect the central nervous system. In this sense, the present study aimed to evaluate the effect of physical exercise in dynamic balance, motor coordination, exploratory locomotor activity and in the oxidative and immunological balance of rats treated with vincristine (VCR). For that, 40 adult rats were divided into two groups: exercise group (6 weeks of swimming, 1h/day, 5 days/week, with overload of 5% of body weight) and sedentary group. After training, rats were treated with 0.5 mg/kg of vincristine sulfate for two weeks or with the same dose of 0.9% NaCl. The behavioral tests were conducted 1 and 7 days after each dose of VCR. On day 15 we carried out the biochemical analyzes of the cerebellum. The physical exercise was able to protect against the loss of dynamic balance and motor coordination and, had effect per se in the exploratory locomotor activity, and neutralize oxidative stress, damage DNA and immune damage caused by VCR up to 15 days after the end of the training protocol. In conclusion, we observed that previous physical training protects of the damage motor induced by vincristine.Key-words: exercise, oxidative stress, neuroprotection, cerebellum.


2011 ◽  
Vol 15 (1) ◽  
pp. 30-40 ◽  
Author(s):  
Joanna Kruk

2017 ◽  
Vol 44 (4) ◽  
pp. 288-293 ◽  
Author(s):  
Shiho Yamadera ◽  
Yuya Nakamura ◽  
Masahiro Inagaki ◽  
Isao Ohsawa ◽  
Hiromichi Gotoh ◽  
...  

Aim: To examine the effects of vitamin E-coated dialyzer on oxidative stress in vitro. Methods: A dialyzer with a synthetic polymer membrane (APS-11SA) and vitamin E-coated dialyzer (VPS-11SA) were connected to a blood tubing line, and U937 cells were circulated in the device. The circulating fluid was collected at 1, 2, 5, 10, 25, and 50 cycles, which are estimated numbers of passes through the dialyzer. Intracellular reactive oxygen species (ROS) production, malondialdehyde (MDA), and Cu/Zn-superoxide dismutase (SOD) were quantified. Results: Intracellular ROS production was increased in the first cycle by APS-11SA and was decreased throughout the experiment by VPS-11SA. Intracellular ROS production in the VPS-11SA device was lower, and MDA levels were decreased. MDA levels were lower during VPS-11SA processing than during APS-11SA processing. Cu/Zn-SOD levels remained unchanged. Conclusion: Our results highlight anti-oxidative-stress effects of a vitamin E-coated dialyzer.


2014 ◽  
Vol 5 (12) ◽  
pp. 3107-3116 ◽  
Author(s):  
Cristian Del Bo’ ◽  
Marisa Porrini ◽  
Daniela Fracassetti ◽  
Jonica Campolo ◽  
Dorothy Klimis-Zacas ◽  
...  

Cigarette smoking causes oxidative stress, hypertension and endothelial dysfunction.


2021 ◽  
pp. 111562
Author(s):  
Marcelo Paes de Barros ◽  
André Luís Lacerda Bachi ◽  
Juliana de Melo Batista dos Santos ◽  
Rafael Herling Lambertucci ◽  
Rafael Ishihara ◽  
...  

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