Penicillin-Induced Oxidative Stress: Effects on Antioxidative Response of Midgut Tissues in Instars of Galleria mellonella

2007 ◽  
Vol 100 (5) ◽  
pp. 1533-1541 ◽  
Author(s):  
E. Buyukguzel ◽  
Y. Kalender
Keyword(s):  
Oxidative Stress ◽  
Galleria Mellonella ◽  
Stress Effects ◽  
Antioxidative Response

scholarly journals Vitamin E-Coated Dialyzer Inhibits Oxidative Stress

2017 ◽  
Vol 44 (4) ◽  
pp. 288-293 ◽  
Author(s):  
Shiho Yamadera ◽  
Yuya Nakamura ◽  
Masahiro Inagaki ◽  
Isao Ohsawa ◽  
Hiromichi Gotoh ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Synthetic Polymer ◽  
Intracellular Reactive Oxygen Species ◽  
Ros Production ◽  
Oxygen Species ◽  
In Vitro Methods ◽  
Stress Effects ◽  
Intracellular Ros

Aim: To examine the effects of vitamin E-coated dialyzer on oxidative stress in vitro. Methods: A dialyzer with a synthetic polymer membrane (APS-11SA) and vitamin E-coated dialyzer (VPS-11SA) were connected to a blood tubing line, and U937 cells were circulated in the device. The circulating fluid was collected at 1, 2, 5, 10, 25, and 50 cycles, which are estimated numbers of passes through the dialyzer. Intracellular reactive oxygen species (ROS) production, malondialdehyde (MDA), and Cu/Zn-superoxide dismutase (SOD) were quantified. Results: Intracellular ROS production was increased in the first cycle by APS-11SA and was decreased throughout the experiment by VPS-11SA. Intracellular ROS production in the VPS-11SA device was lower, and MDA levels were decreased. MDA levels were lower during VPS-11SA processing than during APS-11SA processing. Cu/Zn-SOD levels remained unchanged. Conclusion: Our results highlight anti-oxidative-stress effects of a vitamin E-coated dialyzer.

Comparative evaluation of adolescent repeated psychological or physical stress effects on adult cognitive performance, oxidative stress, and heart rate in female rats

Stress ◽  
2018 ◽  
Vol 22 (1) ◽  
pp. 123-132 ◽  
Author(s):  
Monireh-Sadat Mousavi ◽  
Gholamhossein Riazi ◽  
Alireza Imani ◽  
Sogol Meknatkhah ◽  
Nahid Fakhraei ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Heart Rate ◽  
Cognitive Performance ◽  
Comparative Evaluation ◽  
Physical Stress ◽  
Female Rats ◽  
Stress Effects

scholarly journals Oxidative Stress of Plants: Chemistry, Physiology, Methods of Protection

2021 ◽  
pp. 30-43
Author(s):  
Ekaterina Khozeeva ◽  
◽  
Yuliya Zimina ◽  
Galina Sroslova ◽  
◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Protective Mechanism ◽  
Oxygen Species ◽  
Biotic And Abiotic Stress ◽  
Stress Effects ◽  
Agricultural Plants ◽  
A Chain ◽  
Main Components

Under conditions of biotic and abiotic stress, reactive oxygen species (ROS) are formed in plants, which causes oxidative stress. At the same time, ROS play additional signaling roles in plant adaptation to stress. The study of the mechanisms of this process makes it possible to develop new ways of protecting organisms, in particular, agricultural plants, from negative stress effects. This review describes the current understanding of oxidative stress – the process of inhibition of the vital activity of cells under the action of reactive oxygen species. The distinctive features of plant oxidative stress and two main pathways of metabolic protection – the jasmonate and salicylate pathways – are separately identified. Various ways of identifying oxidative stress are also given. Innovative methods of protecting agricultural plants from oxidative stress are considered: the use of biopesticides – rhizobacteria and microscopic fungi, elicitors – the youngest direction in creating effective methods of protection. It also describes a relatively outdated method of protection – the use of fungicides. These substances were included in the review due to the recent appearance of biodegradable preparations of this type. Special attention is paid to elicitors – substances that are not typical for plants, the appearance of which in the cell causes a chain of biochemical processes similar to the metabolism of plants under oxidative stress. The most studied substances with the properties of elicitors are described: salicylic acid, jasmonates, hytosan and hydrogen peroxide; their role in the chain of response reactions. As an alternative, isothiocyanates – the main components of the “mustard bomb” – the protective mechanism of plants of the cruciferous family are considered. Also, the latest studies of isothiocyanates in the metabolic processes of plants are described.

scholarly journals Recovery from Oxidative Stress: Effects on the Tight Junction in Epithelial Cells.

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
D'Ann E. Arthur ◽  
Jeannette E. Gonzalez ◽  
Jonathan M. King
Keyword(s):  
Oxidative Stress ◽  
Epithelial Cells ◽  
Tight Junction ◽  
Stress Effects

scholarly journals Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension

2019 ◽  
Vol 53 (6) ◽  
pp. 1801524 ◽  
Author(s):  
Kirsty M. Mair ◽  
Katie Y. Harvey ◽  
Alasdair D. Henry ◽  
Dianne Z. Hillyard ◽  
Margaret Nilsen ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Pulmonary Hypertension ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Cytochrome P450 1B1 ◽  
Stress Effects ◽  
Endogenous Oestrogen ◽  
Pulmonary Arterial ◽  
Induced Changes ◽  
Species Production

Obesity is a common comorbidity for pulmonary arterial hypertension (PAH). Additionally, oestrogen and its metabolites are risk factors for the development of PAH. Visceral adipose tissue (VAT) is a major site of oestrogen production; however, the influence of obesity-induced changes in oestrogen synthesis and metabolism on the development of PAH is unclear. To address this we investigated the effects of inhibiting oestrogen synthesis and metabolism on the development of pulmonary hypertension in male and female obese mice.We depleted endogenous oestrogen in leptin-deficient (ob/ob) mice with the oestrogen inhibitor anastrozole (ANA) and determined the effects on the development of pulmonary hypertension, plasma oestradiol and urinary 16α-hydroxyestrone (16αOHE1). Oestrogen metabolism through cytochrome P450 1B1 (CYP1B1) was inhibited with 2,2′,4,6′-tetramethoxystilbene (TMS).ob/ob mice spontaneously develop pulmonary hypertension, pulmonary vascular remodelling and increased reactive oxygen species production in the lung; these effects were attenuated by ANA. Oestradiol levels were decreased in obese male mice; however, VAT CYP1B1 and 16αOHE1 levels were increased. TMS also attenuated pulmonary hypertension in male ob/ob mice. Intra-thoracic fat from ob/ob mice and VAT conditioned media produce 16αOHE1 and can contribute to oxidative stress, effects that are attenuated by both ANA and TMS.Obesity can induce pulmonary hypertension and changes in oestrogen metabolism, resulting in increased production of 16αOHE1 from VAT that contributes to oxidative stress. Oestrogen inhibitors are now in clinical trials for PAH. This study has translational consequences as it suggests that oestrogen inhibitors may be especially beneficial in treating obese individuals with PAH.

scholarly journals Evaluation of the Oxidative Stress Response of Aging Yeast Cells in Response to Internalization of Fluorescent Nanodiamond Biosensors

Nanomaterials ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 372
Author(s):  
Kiran J. van der Laan ◽  
Aryan Morita ◽  
Felipe P. Perona-Martinez ◽  
Romana Schirhagl
Keyword(s):  
Oxidative Stress ◽  
Free Radicals ◽  
Free Radical ◽  
Stress Response ◽  
Cell Metabolism ◽  
High Reactivity ◽  
Magnetic Sensors ◽  
Yeast Cells ◽  
Stress Effects ◽  
Related Stress

Fluorescent nanodiamonds (FNDs) are proposed to be used as free radical biosensors, as they function as magnetic sensors, changing their optical properties depending on their magnetic surroundings. Free radicals are produced during natural cell metabolism, but when the natural balance is disturbed, they are also associated with diseases and aging. Sensitive methods to detect free radicals are challenging, due to their high reactivity and transiency, providing the need for new biosensors such as FNDs. Here we have studied in detail the stress response of an aging model system, yeast cells, upon FND internalization to assess whether one can safely use this biosensor in the desired model. This was done by measuring metabolic activity, the activity of genes involved in different steps and the locations of the oxidative stress defense systems and general free radical activity. Only minimal, transient FND-related stress effects were observed, highlighting excellent biocompatibility in the long term. This is a crucial milestone towards the applicability of FNDs as biosensors in free radical research.

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