Myth: Patients with severe cerebrovascular accidents (CVA) require long-term bladder catheters

Author(s):  
Mary C. Mallappallil
Author(s):  
Atul Batra ◽  
Shiying Kong ◽  
Rodrigo Rigo ◽  
Winson Y Cheung

2014 ◽  
Vol 168 (6) ◽  
pp. 862-868.e1 ◽  
Author(s):  
Elena Guerra ◽  
Gjin Ndrepepa ◽  
Stefanie Schulz ◽  
Robert Byrne ◽  
Petra Hoppmann ◽  
...  

2016 ◽  
Vol 43 (6) ◽  
pp. 509-513 ◽  
Author(s):  
Glen J. Iannucci ◽  
Olufolake A. Adisa ◽  
Matthew E. Oster ◽  
Michael McConnell ◽  
William T. Mahle

Sickle cell disease is a risk factor for cerebrovascular accidents in the pediatric population. This risk is compounded by hypoxemia. Cyanotic congenital heart disease can expose patients to prolonged hypoxemia. To our knowledge, the long-term outcome of patients who have combined sickle cell and cyanotic congenital heart disease has not been reported. We retrospectively reviewed patient records at our institution and identified 5 patients (3 girls and 2 boys) who had both conditions. Their outcomes were uniformly poor: 4 died (age range, 12 mo–17 yr); 3 had documented cerebrovascular accidents; and 3 developed ventricular dysfunction. The surviving patient had developmental delays. On the basis of this series, we suggest mitigating hypoxemia, and thus the risk of stroke, in patients who have sickle cell disease and cyanotic congenital heart disease. Potential therapies include chronic blood transfusions, hydroxyurea, earlier surgical correction to reduce the duration of hypoxemia, and heart or bone marrow transplantation.


2019 ◽  
Vol 8 (11) ◽  
pp. 2006 ◽  
Author(s):  
Giovanni Merlino ◽  
Gian Luigi Gigli ◽  
Francesco Bax ◽  
Anna Serafini ◽  
Elisa Corazza ◽  
...  

Although seizures are frequently seen after cerebrovascular accidents, their effects on long-term outcome in stroke patients are still unknown. Therefore, the aim of this study was to investigate the relationship between post-stroke seizures and the risk of long-term disability and mortality in stroke patients. This study is part of a larger population-based study. All patients were prospectively followed up by a face-to-face interview or a structured telephone interview. We enrolled 635 patients with first-ever stroke and without a history of seizures. Prevalence of ischemic stroke (IS) was 85.2%, while the remaining 14.8% of patients were affected by intracerebral hemorrhage (ICH). During the study period, 51 subjects (8%) developed post-stroke seizures. Patients with post-stroke seizures were younger, had a higher prevalence of ICH, had a more severe stroke at admission, were more likely to have an IS involving the total anterior circulation, and were more likely to have a lobar ICH than patients without seizures. Moreover, subjects with seizures had more frequently hemorrhagic transformation after IS and cortical strokes. At 24 months, the risk of disability in patients with seizures was almost twice than in those without seizures. However, the negative effect of seizures disappeared in multivariate analysis. Kaplan-Meier survival curves at 12 years were not significantly different between patients with and without post-stroke seizures. Using the Cox multivariate analysis, age, NIHSS at admission, and pre-stroke mRS were independently associated with all-cause long-term mortality. In our sample, seizures did not impair long-term outcome in patients affected by cerebrovascular accidents. The not significant, slight difference in favor of a better survival for patients with seizures may be attributed to the slight age difference between the two groups.


1975 ◽  
Author(s):  
B. Guiraud ◽  
J. David ◽  
G. Géraud ◽  
B. Boneu ◽  
R. Biermé ◽  
...  

The purpose of this study is to determine whether antiaggregating drugs are more effective than vasodilators in the prevention of ischemic cerebrovascular accidents.To date, 350 patients are randomly divided into 3 groups and treated as follows: group 1 – hydergin alone (4.5 mg/day); group 2 – hydergin (4.5 mg/day) plus aspirin (1 g/day); group 3 – hydergin (4.5 mg/day) plus aspirin (1 g/day) plus dipyridamole (15 Omg/day).Only those patients with a history of transient ischemic attacks or a regressive stroke with minimal sequellae are included. Patients with coagulopathy, long term anticoagulant or anti-inflammatory treatment, valvulopathy or peptic ulcus are excluded. Cerebral angiography is performed only when indicated. All patients are clinically examined three times a year with platelet aggregation performed at each visit to control correct drug intake.This study, begun on the june 1st 1973, will be followed for a three years period once a total sample population of 400 patients is reached.A preliminary interpretation of the data will be completed.


2019 ◽  
Vol 9 (3) ◽  
pp. 145-159
Author(s):  
Panyun Wu ◽  
Fei Luo ◽  
Zhenfei Fang

Background: Early revascularization can lead to better prognosis in multivessel coronary artery disease (CAD) patients with chronic kidney disease (CKD). However, whether coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) is better remains unknown. Methods: We searched PubMed and the Cochrane Library database from inception until December 9, 2017, for articles that compare outcomes of CABG and PCI in multivessel CAD patients with CKD. We pooled the odds ratios with a fixed-effects model when I2 < 50% or a random-effects model when I2 > 75% and conducted heterogeneity and quality assessments as well as publication bias analyses. Results: A total of 17 studies with 62,343 patients were included. Compared with CABG, the pooled analysis showed that PCI had a lower risk of short-term all-cause death (OR, 0.56; 95% CI, 0.37–0.84) and cerebrovascular accidents (OR, 0.65; 95% CI, 0.53–0.79) but a higher risk of cardiac death (OR, 1.29; 95% CI, 1.21–1.37), myocardial infarction (MI) (OR, 1.73; 95% CI, 1.35–2.21), and repeat revascularization (RR) (OR, 3.9; 95% CI, 2.99–5.09). There was no significant difference in the risk of long-term all-cause death (OR, 1.08; 95% CI, 0.95–1.23) and major adverse cardiac and cerebrovascular events (MACCE) (OR, 1.58; 95% CI, 0.99–2.52) between the PCI and CABG groups. A subgroup analysis restricted to patients treated with dialysis or with PCI-drug-eluting stent yielded similar results. Conclusions: PCI for patients with CKD and multivessel disease (multivessel CAD) had advantages over CABG with regard to short-term all-cause death and cerebrovascular accidents, but disadvantages regarding the risk of myocardial death, MI, and RR; there was no significant difference in the risk of long-term all-cause death and MACCE. Large randomized controlled trials are needed to confirm our findings.


1974 ◽  
Vol 11 (6) ◽  
pp. 375-381
Author(s):  
Sadanobu Kagamimori ◽  
Shunich Kawano ◽  
Akira Okada ◽  
Teturo Kawanishi ◽  
Shozo Azami ◽  
...  

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