Potential of Natural Products for the Prevention of Oral Cancer

Potential Phytochemical Nanoemulsions in the Treatment of Oral Cancer and Oral Health

10.4018/978-1-7998-8378-4.ch015 ◽

2022 ◽

pp. 330-353

Author(s):

Dharmeswar Barhoi ◽

Sweety Nath Barbhuiya ◽

Sarbani Giri

Keyword(s):

Natural Products ◽

Radiation Therapy ◽

Oral Health ◽

Side Effects ◽

Oral Cancer ◽

Medicinal Plants ◽

Drug Development ◽

Health Management ◽

Free Form ◽

New Drug Development

Oral cancer is one of the most common types of cancer, and lifestyle factors like extensive consumption of tobacco, betel quid, and alcohol are the major etiological factors of oral cancer. Treatment of oral cancer includes surgery, radiation therapy, and chemotherapy, but this treatment possesses lots of side effects. Therefore, scientists and medical experts are utilizing natural products and medicinal plants for new drug development. Natural products and phytochemicals showed better efficacy with less toxicity. However, most of the phytochemicals showed poor permeability and less bioavailability. To combat this problem, scientists developed nanosized nanoemulsions of phytochemicals to treat various ailments. Nanoemulsions of phytochemicals exhibited better efficacy than their free form due to increased permeability and bioavailability. Numerous phytopharmaceuticals have been formulated for nanoemulsions to date and tested for their anticancer potential against various cancers, including oral cancer and oral health management.

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Prevention of oral cancer by natural products

International Journal of Preventive and Clinical Dental Research ◽

10.4103/inpc.inpc_22_20 ◽

2020 ◽

Vol 7 (3) ◽

pp. 72

Author(s):

MohamedYaser Kharma ◽

Baydaa Koussa ◽

Mawada Dadoue ◽

Mohammed Daboul ◽

Rania Hasan ◽

...

Keyword(s):

Natural Products ◽

Oral Cancer

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Selective Killing Natural Products and Drugs in Oral Cancer Treatments

Dental Research and Management ◽

10.33805/2572-6978.e101 ◽

2016 ◽

pp. 1-2

Author(s):

Hsueh-Wei Chang

Keyword(s):

Natural Products ◽

Drug Discovery ◽

Side Effects ◽

Oral Cancer ◽

Cancer Cells ◽

Anticancer Drugs ◽

Cancer Treatments ◽

Normal Cells ◽

Killing Effect ◽

Anticancer Drug Discovery

Most cancer drugs are effective to kill cancer cells but also harm normal cells. Drugs and natural products with the selective killing effect may be helpful to solve this problem. The side effects of many anticancer drugs are partly derived from its damage to both cancer and normal cells without selection. This problem raises the need of anticancer drug discovery with the selective killing effect.

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Chemopreventive and Anti-tumor Potential of Natural Products in Oral Cancer

Nutrition and Cancer ◽

10.1080/01635581.2021.1931698 ◽

2021 ◽

pp. 1-17

Author(s):

Andrés Cardona-Mendoza ◽

Geovanny Olivares-Niño ◽

David Díaz-Báez ◽

Gloria Inés Lafaurie ◽

Sandra J. Perdomo

Keyword(s):

Natural Products ◽

Oral Cancer

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Pleiotrophic effects of natural products in ROS-induced carcinogenesis: The role of plant-derived natural products in oral cancer chemoprevention

Cancer Letters ◽

10.1016/j.canlet.2012.02.025 ◽

2012 ◽

Vol 327 (1-2) ◽

pp. 16-25 ◽

Cited By ~ 27

Author(s):

Dominique Ziech ◽

Ioannis Anestopoulos ◽

Rania Hanafi ◽

Georgia Persephoni Voulgaridou ◽

Rodrigo Franco ◽

...

Keyword(s):

Natural Products ◽

Oral Cancer ◽

Cancer Chemoprevention ◽

Pleiotrophic Effects

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Ultrastructural features of prognostic significance in human oral cancer

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100123490 ◽

1992 ◽

Vol 50 (1) ◽

pp. 618-619

Author(s):

Karvita B. Ahluwalia ◽

Nidhi Sharma

Keyword(s):

Oral Cancer ◽

Squamous Cell ◽

Common Knowledge ◽

Prognostic Significance ◽

Growth Control ◽

Terminal Differentiation ◽

Squamous Cell Carcinomas ◽

Effective Therapy ◽

Invasive Potential ◽

Biological Behaviour

It is common knowledge that apparently similar tumors often show different responses to therapy. This experience has generated the idea that histologically similar tumors could have biologically distinct behaviour. The development of effective therapy therefore, has the explicit challenge of understanding biological behaviour of a tumor. The question is which parameters in a tumor could relate to its biological behaviour ? It is now recognised that the development of malignancy requires an alteration in the program of terminal differentiation in addition to aberrant growth control. In this study therefore, ultrastructural markers that relate to defective terminal differentiation and possibly invasive potential of cells have been identified in human oral leukoplakias, erythroleukoplakias and squamous cell carcinomas of the tongue.

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