Next Step Lymphatic Filariasis Eradication: Current Status in the Development of a Vaccine Against Lymphatic Filariasis

2018 ◽  
pp. 33-46
Author(s):  
Ramaswamy Kalyanasundaram
2018 ◽  
Vol 46 (1) ◽  
pp. 11-20
Author(s):  
Hamida Khanum ◽  
Iftekhar Hossain ◽  
Fahmida Sarkar ◽  
Rimi Farhana Zaman

The present study was carried out in Nilphamari district, Filaria Hospital of Nilphamari district and from randomly selected three villages of Nilphamari Sadar and Paurasava, Sayedpur, Domar, Dimla, Joldhaka and Kishoreganj. The objectives of this study were to find out the status of lymphatic filariasis (LF) in Nilphamari district: An endemic area for LF in Bangladesh. The investigation was carried out among the inhabitants of the villages and the outdoor patients of Filaria Hospital in Nilphamari through a formatted questionnaire. The current status of this disease was 4.43% in Nilphamari Sadar and 3.25% in Paurasava, 4.10% in Sayedpur and similarly 4.82% in Domar, 5.86% in Dimla, 3.85% in Joldhaka and 4.70% in Kishoreganj. In Nilphamari district, it was found that male were more susceptible (58.84%) than female (41.16%). 76.22% male patients had hydrocoele and the disease showed its highest prevalence (41.16%) in the age group of 41-60 years.Bangladesh J. Zool. 46(1): 11-19, 2018


2017 ◽  
Vol 33 (10) ◽  
pp. 788-798 ◽  
Author(s):  
Nils Pilotte ◽  
Thomas R. Unnasch ◽  
Steven A. Williams

2016 ◽  
Vol 25 (2) ◽  
pp. 103-111
Author(s):  
Md Khalid Eakbal Anik ◽  
Hamida Khanum ◽  
Iftekhar Ahmed Rizvi ◽  
Shahela Alam ◽  
Hasina Banu

The present study was carried out in Filaria Hospital of Nilphamari to find out the current status of lymphatic filariasis (LF) in Nilphamari district: An endemic area for lymphatic filariasis in Bangladesh. The inhabitants of the villages, the outdoor patients and hospitalized patients in Filaria Hospital were selected for the study. The current status and the prevalence of filariasis in Nilphamari district was 4.43%, in Nilphamari Sadar was 3.25% and 4.10% in Sayedpur, 4.82% in Domar, 5.86% in Dimla, 3.85% in Joldhaka and 4.70% in Kishoreganj. It was found that 58.84% filarial patients were male and 41.16% were female; highest prevalence of the disease was observed at the age group of 41 - 60 years. Illiteracy and poverty are the important social risk factors of this disease , about 45% patients were illiterate. Most of the infected patients were very poor and belong to low income group. Only 40.5% patients knew about filariasis. Only 26.1% patients used mosquito curtains. During the study period, it was found that 66.15% of hospitalized filarial patients were male and 33.85% were female, in the Filaria Hospital of Nilphamari. The highest outdoor patients in Nilphamari Hospital were of age group 40 - 59 years and 76.22% patients had hydrocele. Dhaka Univ. J. Biol. Sci. 25(2): 103-111, 2016 (July)


2016 ◽  
Vol 14 (1) ◽  
pp. 1-2 ◽  
Author(s):  
Md. Moazzem Hossain

No Abstract is available Journal of Science Foundation 2016;14(1):1-2


2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Happyness J. Mshana ◽  
Vito Baraka ◽  
Gerald Misinzo ◽  
Williams H. Makunde

Background. Tanzania started a countrywide lymphatic filariasis elimination programme in 2000 adopting the mass drug administration (MDA) strategy. The drug used for the programme was the combination of ivermectin and albendazole. However, there is limited information on the current epidemiological trend of the infections, where MDA implementation is ongoing. The present study aimed at assessing the current status of Bancroftian filariasis infection rate and morbidity where MDA has been distributed and administered for over eight rounds. Methodology. The study was a cross-sectional descriptive study involving 272 individuals (>18 years) from endemic communities in Tanga region where MDA has been implemented. Clinical, sociodemographic, and circulating filarial antigen (CFA) test was undertaken using immune chromatographic card test according to the manufacturer’s instructions. Results. A total of 472 individuals were screened: 307/472 (65.1%) were males while 165/472 (34.9%) were females. The overall prevalence of CFA was 5.51%, that of hydrocoele was 73.2%, and that of lymphoedema was 16.0%. The prevalence of hydrocoele combined with lymphoedema was 5.5%. Conclusion. Our findings demonstrate a considerable reduction in filarial infection. However, there is clear evidence of ongoing transmission despite the 8 rounds of MDA. It is unlikely that the annual MDA would interrupt filarial transmission; therefore, additional strategies are needed to accelerate lymphatic filariasis control and elimination.


2020 ◽  
Vol 52 (03) ◽  
pp. 17-21
Author(s):  
Srivastava Pradeep Kumar ◽  

The journey towards elimination of Lymphatic Filariasis (ELF) in India started with the deliberations in a meeting held at Delhi in 1996 recommending for pilot project of Mass Drug Administration (MDA) with DEC. Global Programme to Eliminate Lymphatic Filariasis (GPELF was launched in 2000 subsequent to World Health Assembly (WHA) resolution in 1997 making India as signatory. ELF campaign was launched on 5th June, 2004 with annual MDA in endemic districts. However, all the endemic districts could not initiate MDA due to logistics and preparedness issues, thus the journey initially experienced challenges of hurried start. Serious Adverse Events (SAE) and poor compliance were reported from many states which were tackled through advocacy and capacity building of health workers and community volunteers. MDA was managed with staggering of dates in different states and strong supervision helped in improving drug compliance. The improved reported drug coverage resulted in decline of microfilaria prevalence in many districts except some districts. India’s significant progress was recognised internationally as approximately 200 of 650 million population at risk of Lymphatic Filariasis (LF) was made free of risk by 2017 by passing Transmission Assessment Survey (TAS) though some districts could not clear TAS. Efforts to improve drug compliance were intensified and to achieve goal faster, MDA with three drug Ivermectin, DEC and Albendazole has been initiated in addition to ascertaining the current status of LF endemicity in non-MDA districts. Based on experience of long journey towards ELF with mix of success and challenges, it is suggested to intensify ELF in a mission mode with priority.


2018 ◽  
Vol 12 (5) ◽  
pp. e0006472 ◽  
Author(s):  
Nilmini Chandrasena ◽  
Ranjan Premaratna ◽  
Indeewarie. E. Gunaratna ◽  
Nilanthi R. de Silva

1966 ◽  
Vol 25 ◽  
pp. 266-267
Author(s):  
R. L. Duncombe

An examination of some specialized lunar and planetary ephemerides has revealed inconsistencies in the adopted planetary masses, the presence of non-gravitational terms, and some outright numerical errors. They should be considered of temporary usefulness only, subject to subsequent amendment as required for the interpretation of observational data.


Sign in / Sign up

Export Citation Format

Share Document