Arsenic Exposure and Lifestyle-Related Diseases

In the near future, it is expected that the prevalence of illnesses related to the increasing life expectancies and quality of life, such as neurodegenerative diseases and cardiovascular diseases related to metabolic disorders, will soar to unprecedented levels, leading to high socioeconomic costs. To address this rising threat, natural products are emerging as a novel strategy for the prevention and therapy of these ages- and lifestyle-related diseases, thanks to their high marketability and few side effects. In this patent review, we summarize selected patents for food supplements, functional and fortified foods, filed from 2016 to 2019, categorizing them based on the biological activity of their components.

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Arsenic-contaminated cold-spring water in mountainous areas of Hui County, Northwest China: A new source of arsenic exposure

The Science of The Total Environment ◽

10.1016/j.scitotenv.2011.08.055 ◽

2011 ◽

Vol 409 (24) ◽

pp. 5513-5516 ◽

Cited By ~ 1

Author(s):

Qiang Zhang ◽

Quanmei Zheng ◽

Guifan Sun

Keyword(s):

Arsenic Exposure ◽

Northwest China ◽

Spring Water ◽

Mountainous Areas ◽

Cold Spring

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The Current View of Nonalcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma

Cancers ◽

10.3390/cancers13030516 ◽

2021 ◽

Vol 13 (3) ◽

pp. 516

Author(s):

Tomomi Kogiso ◽

Katsutoshi Tokushige

Keyword(s):

Hepatocellular Carcinoma ◽

Liver Disease ◽

Fatty Liver ◽

Nonalcoholic Fatty Liver Disease ◽

Fatty Liver Disease ◽

Current View ◽

Nonalcoholic Fatty Liver ◽

Obesity And Diabetes ◽

Life Threatening ◽

Lifestyle Related Diseases

Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome and can develop into hepatocellular carcinoma (HCC). The incidence of NAFLD-related HCC, which is accompanied by life-threatening complications, is increasing. Advanced fibrosis and lifestyle-related and metabolic comorbidities, especially obesity and diabetes mellitus, are associated with HCC development. However, HCC is also observed in the non-cirrhotic liver. Often, diagnosis is delayed until the tumor is relatively large and the disease is advanced; an effective screening or surveillance method is urgently required. Recently, the NAFLD/nonalcoholic steatohepatitis (NASH) guidelines of Japan were revised to incorporate new strategies and evidence for the management and surveillance of NAFLD/NASH. Fibrosis must be tested for noninvasively, and the risk of carcinogenesis must be stratified. The treatment of lifestyle-related diseases is expected to reduce the incidence of NAFLD and prevent liver carcinogenesis.

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