A Review of Recent Patents (2016-2019) on Plant Food Supplements with Potential Application in the Treatment of Neurodegenerative and Metabolic Disorders

2020 ◽  
Vol 11 (2) ◽  
pp. 145-153 ◽  
Author(s):  
Rosalba Leuci ◽  
Leonardo Brunetti ◽  
Antonio Laghezza ◽  
Paolo Tortorella ◽  
Fulvio Loiodice ◽  
...  
Keyword(s):  
Metabolic Disorders ◽  
Food Supplements ◽  
Plant Food ◽  
Fortified Foods ◽  
Patent Review ◽  
Novel Strategy ◽  
Lifestyle Related Diseases ◽  
Near Future ◽  
Prevention And Therapy

In the near future, it is expected that the prevalence of illnesses related to the increasing life expectancies and quality of life, such as neurodegenerative diseases and cardiovascular diseases related to metabolic disorders, will soar to unprecedented levels, leading to high socioeconomic costs. To address this rising threat, natural products are emerging as a novel strategy for the prevention and therapy of these ages- and lifestyle-related diseases, thanks to their high marketability and few side effects. In this patent review, we summarize selected patents for food supplements, functional and fortified foods, filed from 2016 to 2019, categorizing them based on the biological activity of their components.

Assessment of the quality of life in the treatment approaches of patients with the comorbid course of arterial hypertension and metabolic disorders aimed at reducing cardiovascular risk

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
V Zlatkina ◽  
V Shkapo ◽  
A Nesen ◽  
T Starchenko
Keyword(s):  
Quality Of Life ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Arterial Hypertension ◽  
Metabolic Disorders ◽  
Clinical Signs ◽  
Blood Analysis ◽  
Sf 36 ◽  
Artery Disease

Abstract Funding Acknowledgements Type of funding sources: None. Introduction. Cardiovascular diseases (CVD) remain the leading cause of premature death worldwide. According to epidemiological studies CVD prevention is highly effective. A 50% reduction in mortality from coronary artery disease (CAD) is associated with exposure to risk factors and only 40% with improved treatment. Purpose.  To assess the quality of life (QOL) in patients with arterial hypertension (AH) and metabolic disorders, to establish its impact on therapy effectiveness. We examined 280 patients with AH and comorbidity - 171 women and 109 men aged 45-75 years. Along with AH, all patients had comorbidities: 72.6 % suffered from coronary artery disease (CAD), 10.5% after myocardial infarction (MI), 35 % had clinical signs of heart failure (HF), 22, 1% - type 2 diabetes mellitus (t2DM), 27.4% - chronic kidney disease (CKD). Methods. Anthropometry, blood pressure (BP) measurement, immunoassay (C-reactive protein), biochemical blood analysis (lipid, carbohydrate metabolism parameters, QOL determination (questionnaire Sf-36). Results. In patients with comorbidity of pathologies (presence of AH, t2DM, CKD, CAD, obesity), there was a decrease in assessments in almost all indicators of QOL, and especially significant limitations in the performance of daily activities due to both physical and mental state. Conclusion. The degree of AH in patients with t2DM decreased QOL of physical activity, role-physical functioning, pain and general health, reflecting physical health, as well as mental health, including vitality, social activity, role emotional functioning. T2DM in patients with AH significantly worsens QOL of this category of patients as in physical component summary and mental component summary. The indicators of QOL are significantly affected by the duration of t2DM, as well as the degree of compensation. Achievement of the target BP levels in patients with AH with t2DM shows an improvement in a number of QOL parameters and makes it possible to recommend the Sf-36 questionnaire as a criterion for the effectiveness of the therapy.

Ever-Single Heterosexual Couples in Nonmarital Cohabitation: Spirituality, Connectedness, and Adjustment

2021 ◽  
pp. 106648072110239
Author(s):  
Samta P. Pandya
Keyword(s):  
Middle Class ◽  
Relationship Quality ◽  
Upper Class ◽  
Heterosexual Couples ◽  
Highly Qualified ◽  
Christian Couples ◽  
Work Intervention ◽  
Do It Yourself ◽  
Near Future

This article reports a study on the effectiveness of WhatsApp-based spiritual posts in promoting connectedness and adjustment among ever-single heterosexual couples in nonmarital cohabitation in four global cities. In comparison with trivia posts, the spiritual posts had greater impact and were more effective for Christian couples, middle class, highly qualified, and professionals-salaried cohabitants. This was in comparison with Hindu–Buddhist–Sikh dyads, upper class, with college degree, and entrepreneurs. However, cohabitation duration, initial cohabitation experience with other partners, having children/cohabitation dependents, and near future marriage plans were not significant predictors. Gender also did not significantly moderate spiritual intervention responses as proposed in the previous research. Couple intervention outcomes were mutually interdependent and intervention compliance in terms of number of posts read and do-it-yourself exercises posted were robust predictors of intervention success. With some subgroup-specific refinements, WhatsApp-based spiritual posts would be an effective spiritually sensitive social work intervention for improving relationship quality of nonmarital cohabitants.

scholarly journals OP0277-PARE METABERN, THE EUROPEAN REFERENCE NETWORK FOR RARE HEREDITARY DISEASES: STRUCTURE, OBJECTIVES, METABOLIC RMDS AND THE ROLES OF EUROPEAN PATIENT ADVOCACY GROUPS (EPAGS)

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 168.2-168
Author(s):  
L. Wagner ◽  
S. Sestini ◽  
C. Brown ◽  
A. Finglas ◽  
R. Francisco ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Care ◽  
Social Science ◽  
Metabolic Pathways ◽  
Metabolic Disorders ◽  
Clinical Care ◽  
Single Point ◽  
Link Type ◽  
The Impact

Background:Inborn metabolic disorders (IMDs) currently encompass more than 1,500 diseases with new ones still to be identified1. Each of them is characterised by a genetic defect affecting a metabolic pathway. Only few of them have curative treatments, that target the respective metabolic pathway. Commonly, treatment examples include diet, substrate reduction therapies, enzyme replacement therapies, gene therapy and biologicals, enabling IMD-patient now to survive to adulthood. About 30 % of all IMDs involve the musculoskeletal system and are here referred to as rare metabolic RMDs. Generally, IMDs are very heterogenous with respect to symptoms and severity, often being systemic and affecting more children than adults. Thus, challenges include certified advanced training of adult metabolic experts, standardised transition plans, social support and development of therapies for diseases that do not have any cure yet.Objectives:Introduction of MetabERN, its structure and objectives, highlighting on the unique features and challenges of metabolic RMDs and describing the involvement of patient representation in MetabERN.Methods:MetabERN is stratified in 7 subnetworks (SNW) according to the respective metabolic pathways and 9 work packages (WP), including administration, dissemination, guidelines, virtual counselling framework, research/clinical trials, continuity of care, education and patient involvement. The patient board involves a steering committee and single point of contacts for each subnetwork and work package, respectively2. Projects include identifying the need of implementing social science to assess the psycho-socio-economic burden of IMDs, webinars on IMDs and their transition as well as surveys on the impact of COVID-193 on IMD-patients and health care providers (HCPs), social assistance for IMD-patients and analysing the transition landscape within Europe.Results:The MetabERN structure enables bundling of expertise, capacity building and knowledge transfer for faster diagnosis and better health care. Rare metabolic RMDs are present in all SNWs that require unique treatments according to their metabolic pathways. Implementation of social science to assess the psycho-socio-economic burden of IMDs is still underused. Involvement of patient representatives is essential for a holistic healthcare not only focusing on clinical care, but also on the quality of life for IMD-patients. Surveys identified unmet needs of patient care, patients having little information on national support systems and structural deficits of healthcare systems to ensure HCP can provide adequate clinical care during transition phases. These results are collected by MetabERN and forwarded to the Directorate-General for Health and Food Safety (DG SANTE) of the European Commission (EC) to be addressed further.Conclusion:MetabERN offers an infrastructure of virtual healthcare for patients with IMDs. Thus, in collaboration with ERN ReCONNET, MetabERN can assist in identifying rare metabolic disorders of RMDs to shorten the odyssey of diagnosis and advise on their respective therapies. On the other hand, MetabERN can benefit from EULAR’s longstanding experience regarding issues affecting the quality of life, all RMD patients are facing, such as pain, stiffness, fatigue, rehabilitation, maintaining work and disability claims.References:[1]IEMbase - Inborn Errors of Metabolism Knowledgebase http://www.iembase.org/ (accessed Jan 29, 2021).[2]MetabERN: European Refence Network for Hereditary Metabolic Disorders https://metab.ern-net.eu/ (accessed Jan 29, 2021).[3]Lampe, C.; Dionisi-Vici, C.; Bellettato, C. M.; Paneghetti, L.; van Lingen, C.; Bond, S.; Brown, C.; Finglas, A.; Francisco, R.; Sestini, S.; Heard, J. M.; Scarpa, M.; MetabERN collaboration group. The Impact of COVID-19 on Rare Metabolic Patients and Healthcare Providers: Results from Two MetabERN Surveys. Orphanet J. Rare Dis.2020, 15 (1), 341. https://doi.org/10.1186/s13023-020-01619-x.Acknowledgements:The authors thank the MetabERN collaboration group, the single point of contacts (SPOC) of the MetabERN patient board and the Transition Project Working Group (TPWG)Disclosure of Interests:None declared

scholarly journals Toward a Better Understanding of Metal Nanoparticles, a Novel Strategy from Eucalyptus Plants

Plants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 929
Author(s):  
Hanadi Sawalha ◽  
Rambod Abiri ◽  
Ruzana Sanusi ◽  
Noor Azmi Shaharuddin ◽  
Aida Atiqah Mohd Noor ◽  
...  
Keyword(s):  
Metal Nanoparticles ◽  
Woody Plants ◽  
Woody Species ◽  
Forest Products ◽  
Ideal Candidate ◽  
Promising Tool ◽  
Novel Strategy ◽  
The Ideal

Nanotechnology is a promising tool that has opened the doors of improvement to the quality of human’s lives through its potential in numerous technological aspects. Green chemistry of nanoscale materials (1–100 nm) is as an effective and sustainable strategy to manufacture homogeneous nanoparticles (NPs) with unique properties, thus making the synthesis of green NPs, especially metal nanoparticles (MNPs), the scientist’s core theme. Researchers have tested different organisms to manufacture MNPs and the results of experiments confirmed that plants tend to be the ideal candidate amongst all entities and are suitable to synthesize a wide variety of MNPs. Natural and cultivated Eucalyptus forests are among woody plants used for landscape beautification and as forest products. The present review has been written to reflect the efficacious role of Eucalyptus in the synthesis of MNPs. To better understand this, the route of extracting MNPs from plants, in general, and Eucalyptus, in particular, are discussed. Furthermore, the crucial factors influencing the process of MNP synthesis from Eucalyptus as well as their characterization and recent applications are highlighted. Information gathered in this review is useful to build a basis for new prospective research ideas on how to exploit this woody species in the production of MNPs. Nevertheless, there is a necessity to feed the scientific field with further investigations on wider applications of Eucalyptus-derived MNPs.

To Make a Choice You Should Know The Option Physiological and Psychological Contribution of the Female Component in National Security and Intelligence

2021 ◽  
Vol 2 (1) ◽  
pp. 36-51
Author(s):  
Sabrina Magris
Keyword(s):  
National Security ◽  
Intelligence Community ◽  
Left Behind ◽  
The World ◽  
Two Factors ◽  
Female Component ◽  
Near Future ◽  
Ways Of Being

The paper addresses the importance of the role of women in Intelligence and National Security with the specific purpose to highlight the quality of female contribution in all different domains. The world is changing and in this change, Intelligence risks being left behind as never before. An epic evolution and change are underway that will upset ways of being and ways of thinking. All this not suddenly and all this without realizing it if not after the fact. The world is changing, women “are gain the upper hand” taking over also numerically and it is not realized that a change must happen in the field of Intelligence with a space left to women, not because they are women but because of their abilities. In all domains, from strategic to an operational one. Blindness to change that many Agencies are having. And those who are making changes often do so because they are obliged by the rules but not by evaluating the concrete capability of individuals. Two factors risk being explosive if no action is taken. The paper highlights the physiological and psychological contribution of the female component in the National Security and Intelligence work, and why diversity is scientifically important to successfully conduct operational and strategic tasks. It also describes the existing lack of models, how to enlarge the interest of young girls to join the Intelligence Community, and a look into the near future regarding the training and the recruitment processes with specific regards to women.

scholarly journals Treatment of Chemotherapy-induced Nausea in Cancer Patients

2010 ◽  
Vol 06 (02) ◽  
pp. 14
Author(s):  
Julie L Ryan ◽  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Metabolic Disorders ◽  
Nausea And Vomiting ◽  
Daily Functioning ◽  
Evidence Based ◽  
Nutritional Depletion

For over 30 years, chemotherapy-induced nausea and vomiting have been the most severe and troublesome symptoms for cancer patients receiving chemotherapy. Unresolved chemotherapy-induced nausea and vomiting can lead to metabolic disorders, dehydration, nutritional depletion and oesophageal tears, and can reduce the daily functioning and quality of life of and interfere with treatment schedules. Despite the widespread use of antiemetics, chemotherapy-induced nausea continues to be problematic. Unlike vomiting, nausea is a subjective and unobservable phenomenon, making it extremely difficult to accurately assess and treat. Current research suggests that management of chemotherapy-induced nausea should focus on treating the symptoms before they occur rather than after they develop. This article highlights evidence-based interventions for the treatment of chemotherapy-related nausea.

scholarly journals CHANNEL ALLOCATION FOR WIRELESS NETWORKS BASED ON INTELLIGENT METHOD

2021 ◽  
Vol 20 (4) ◽  
pp. 32-37
Author(s):  
Dominik NEZNÍK ◽  
◽  
Ľubomír DOBOŠ
Keyword(s):  
Wireless Networks ◽  
Data Transfer ◽  
Channel Allocation ◽  
Smart Cities ◽  
Data Rates ◽  
Different Types ◽  
Fuzzy Logic Method ◽  
Network Technologies ◽  
Near Future

In this paper, will be presented actual research of the intelligent channel allocation. The intelligent channel allocation is based on combination of fuzzy logic method and game theory attributes to increase quality of link in network. The channel allocations will become an important phenomenon in different types of networks such as 5G technology, wireless networks (IEEE 802.11xx), Z-Wave, LoRa, 3G, 4G, etc. In the near future, new network technologies, Internet of Things (IoT) and Smart Cities will need to have intelligent channel allocation to prevent interference on the channels used for data transfer. These networks along with IoT are considered as promising technology, that interconnects different types of networks into one fully functional network. The aim of this paper is to present the concept of a methods for channel allocation in wireless networks, where channels work as communication medium based on IEEE 802.11xx technology. The simulations prove, that proposed method is able to provide lower interference, improve data rates and increase quality of links.

scholarly journals Peer Assessment in Writing: A Critical Review of Previous Studies

2019 ◽  
Vol 10 ◽  
pp. 1478-1487
Author(s):  
Sonia Dutta Gupta ◽  
Fatimah Abdullah ◽  
Gu Li ◽  
Yang Xueshuang
Keyword(s):  
Foreign Language ◽  
Critical Review ◽  
English Language ◽  
Assessment Tool ◽  
Peer Assessment ◽  
Student Centered ◽  
Efl Context ◽  
Effective Assessment ◽  
Near Future

Peer assessment has attracted more attention an effective assessment tool in recent years. Peer assessment refers to the arrangement for peers to consider the quality of learning outcomes of others of similar status, it received attention of various studies due to the growing interest in the student centered approach as learners need to be involved in the learning process even in the assessment. This paper is a critical review of previous studies on peer assessment in English as Second/Foreign Language (ESL/EFL) context. Fifteen peer assessment studies from 2004 to 2017 were extensively reviewed and systematically analyzed. Peer assessment of  the reviewed studies were on the quality of the writing outcomes of students in the EFL/ESL contexts, as writing skill occupies an important role in teaching English language.  As a critical review paper of these studies, this paper highlights practical use of peer assessment and the important challenges or issues that need to be considered when utilizing peer assessment in the classroom. This paper hopes that practical measures of peer assessment will be utilized effectively by educators in the ESL and EFL classrooms in the near future.

scholarly journals Toward an intercultural approach to evaluation: A perspective from INEE in Mexico

2018 ◽  
Vol 26 ◽  
pp. 52
Author(s):  
Sylvia Schmelkes
Keyword(s):  
Standardized Tests ◽  
Cultural Context ◽  
Teaching Profession ◽  
Quality Of Education ◽  
Indigenous Students ◽  
Item Development ◽  
Starting Point ◽  
Indigenous Children ◽  
Near Future

The National Institute for the Evaluation of Education (INEE) in Mexico has begun to meet the challenges in evaluating indigenous children and teachers and the educational programs and policies targeted to them. Several evaluation projects are described in this paper. One is the “Previous, Free and Informed Consultation of Indigenous People,” which focuses on quality of education they receive. A second is the design of a protocol for reducing cultural and linguistic bias in standardized tests, which requires oversampling of indigenous students and the involvement of anthropologists, linguists and indigenous teachers in item development. A third is an indigenous language evaluation for candidates for entry into the teaching profession, which they must pass before they can work in indigenous schools. A fourth is the development of a qualitative instrument for evaluating teacher performance. The instrument asks evaluated teachers to contextualize their planning; scorers decide whether the plan is adapted to the cultural context and the characteristics of the children. The projects described are only a starting point. In the near future, several dilemmas, such as the apparent trade-off between contextualization and quality, have to be faced and solved.

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