Comparison of Germplasm Evaluation Parameters

Author(s):  
Jayalakshmi Narayan Hegde ◽  
Sandeep Singh

Information sharing among the associations is a general development in a couple of zones like business headway and exhibiting. As bit of the touchy principles that ought to be kept private may be uncovered and such disclosure of delicate examples may impacts the advantages of the association that have the data. Subsequently the standards which are delicate must be secured before sharing the data. In this paper to give secure information sharing delicate guidelines are bothered first which was found by incessant example tree. Here touchy arrangement of principles are bothered by substitution. This kind of substitution diminishes the hazard and increment the utility of the dataset when contrasted with different techniques. Examination is done on certifiable dataset. Results shows that proposed work is better as appear differently in relation to various past strategies on the introduce of evaluation parameters.


Author(s):  
Tulsi Bisht ◽  
Rishishwar Poonam

The aim of present work was to develop once daily sustained release matrix tablet of aceclofenac by wet granulation technique using natural gums i.e.: gum acacia, guar gum and Xanthan gum. In this present study matrix tablets were prepared using three different methods and a comparative study was done. Aceclofenac sodium being the newer derivative of diclofenac having short biological half life (4hrs.), so it requires more than one dose per day to maintain therapeutic dose. The prepared tablets were evaluated for various parameters like weight variation, hardness, swelling index, friability, percent drug release and various release profile like zero order, first order, Higuchi's, and Koshemeyrs-peppa. All the evaluation parameters met pharmacopoeial specifications and through dissolution studies it was matrix tablets prepared with method 2 shows heighest percent drug release and matrix tablet prepared by method 3 showed lowest percent drug release at the end of 8 hrs. (Shown in fig. 8, comparative release study of all three formulations). Matrix tablet of aceclofenac were successfully prepared and evaluated and it can be concluded that matrix tablet prepared with natural gums showed release rate for a prolonged time and can be of great importance for “once daily” tablet to reduce side effects and toxicity related with NSAIDs.  


2014 ◽  
Vol 4 (2) ◽  
Author(s):  
Dr. Rakesh Chandra ◽  
Mr. Pravesh Dwivedi ◽  
Dr. Ritesh Dwivedi

Universal immunization of children against common vaccine preventable diseases is the most important aspect of childcare programs. It has long been a goal of the Universal Immunization Program. National Population Policy, 2000 has also stressed on development of Indian Immunization Program, as India is one of the largest in the world, in terms of quantities of vaccines used, numbers of beneficiaries, and the numbers of immunization sessions organized. This program is spread all across the country and seven vaccines are used to protect children and pregnant mothers against tuberculosis, diphtheria, pertusis, polio, measles tetanus and hepatitis-B. Some other supplements like vitamin A and iron tablets have also been added with this delivery mechanism to support overall nutritional level of children and their mothers. To assess the grassroot level condition, this study has tried to explore and compare the different parameters related to routine vaccination and supplement distribution in some selected districts. Role of ASHAs and ANMs is very important for this whole immunization program and to enhance the coverage in qualitative manner, certain evaluation parameters must be established like how many households are aware of sanitation, hygiene, preventive health and healthy lifestyle through ASHA and ANM work.


Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2803
Author(s):  
Rabeea Jaffari ◽  
Manzoor Ahmed Hashmani ◽  
Constantino Carlos Reyes-Aldasoro

The segmentation of power lines (PLs) from aerial images is a crucial task for the safe navigation of unmanned aerial vehicles (UAVs) operating at low altitudes. Despite the advances in deep learning-based approaches for PL segmentation, these models are still vulnerable to the class imbalance present in the data. The PLs occupy only a minimal portion (1–5%) of the aerial images as compared to the background region (95–99%). Generally, this class imbalance problem is addressed via the use of PL-specific detectors in conjunction with the popular class balanced cross entropy (BBCE) loss function. However, these PL-specific detectors do not work outside their application areas and a BBCE loss requires hyperparameter tuning for class-wise weights, which is not trivial. Moreover, the BBCE loss results in low dice scores and precision values and thus, fails to achieve an optimal trade-off between dice scores, model accuracy, and precision–recall values. In this work, we propose a generalized focal loss function based on the Matthews correlation coefficient (MCC) or the Phi coefficient to address the class imbalance problem in PL segmentation while utilizing a generic deep segmentation architecture. We evaluate our loss function by improving the vanilla U-Net model with an additional convolutional auxiliary classifier head (ACU-Net) for better learning and faster model convergence. The evaluation of two PL datasets, namely the Mendeley Power Line Dataset and the Power Line Dataset of Urban Scenes (PLDU), where PLs occupy around 1% and 2% of the aerial images area, respectively, reveal that our proposed loss function outperforms the popular BBCE loss by 16% in PL dice scores on both the datasets, 19% in precision and false detection rate (FDR) values for the Mendeley PL dataset and 15% in precision and FDR values for the PLDU with a minor degradation in the accuracy and recall values. Moreover, our proposed ACU-Net outperforms the baseline vanilla U-Net for the characteristic evaluation parameters in the range of 1–10% for both the PL datasets. Thus, our proposed loss function with ACU-Net achieves an optimal trade-off for the characteristic evaluation parameters without any bells and whistles. Our code is available at Github.


Author(s):  
Seong-Hyeon Kang ◽  
Ji-Youn Kim

The purpose of this study is to evaluate the various control parameters of a modeled fast non-local means (FNLM) noise reduction algorithm which can separate color channels in light microscopy (LM) images. To achieve this objective, the tendency of image characteristics with changes in parameters, such as smoothing factors and kernel and search window sizes for the FNLM algorithm, was analyzed. To quantitatively assess image characteristics, the coefficient of variation (COV), blind/referenceless image spatial quality evaluator (BRISQUE), and natural image quality evaluator (NIQE) were employed. When high smoothing factors and large search window sizes were applied, excellent COV and unsatisfactory BRISQUE and NIQE results were obtained. In addition, all three evaluation parameters improved as the kernel size increased. However, the kernel and search window sizes of the FNLM algorithm were shown to be dependent on the image processing time (time resolution). In conclusion, this work has demonstrated that the FNLM algorithm can effectively reduce noise in LM images, and parameter optimization is important to achieve the algorithm’s appropriate application.


Author(s):  
REHANA BEGUM A. ◽  
GANESH N. S. ◽  
VINEETH CHANDY

This review article deals with the various pelletization techniques utilized in the pharmaceutical industry for spheroidal particle production i.e., pellet for mainly oral administration which can be further formulated into several other dosage forms such as tablets, capsules or can be administered as such. Now-a-days oral administration has become the most versatile, convenient and common route of drug administration which ultimately focuses on patient compliance. The technique which is setting horizon in pelletization is “Extrusion Spheronization” because of its simple and easy steps involved in pellet production in a faster way. This review also includes the characterization and evaluation of pellets to ensure its quality, safety and efficacy to give out the required therapeutic activity after administration.


2013 ◽  
Vol 56 (5) ◽  
pp. 710-717 ◽  
Author(s):  
YanJun Li ◽  
Huan Liu ◽  
LieHui Zhang ◽  
ZongGang Lu ◽  
QiRong Li ◽  
...  

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