Malignant mesenchymomas of soft tissue associated with numerous osteoclast-like giant cells mimicking the so-called giant cell variant of ?malignant fibrous histiocytoma?

1994 ◽  
Vol 424 (5) ◽  
Author(s):  
T. Mentzel ◽  
C. Fletcher
Keyword(s):  
Soft Tissue ◽  
Giant Cell ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Giant Cells ◽  
Cell Variant

scholarly journals Malignant Fibrous Histiocytoma in Dogs and Cats

1979 ◽  
Vol 16 (2) ◽  
pp. 199-208 ◽  
Author(s):  
C. A. Gleiser ◽  
G. L. Raulston ◽  
J. H. Jardine ◽  
K. N. Gray
Keyword(s):  
Soft Tissue ◽  
Giant Cell ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Soft Tissue Tumors ◽  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas ◽  
Multinucleated Cells ◽  
Cell Variant ◽  
And Function

Five soft tissue tumors of varied morphology in dogs and cats were classified as malignant fibrous histiocytomas on the basis of their histologic composition. All were composed of varying mixtures of histiocytes and fibroblasts and three contained large multinucleated cells. This giant cell variant of malignant fibrous histiocytoma was seen only in cats. These tumors are comparable to those described in man as malignant fibrous histiocytoma on the basis of the malignant histiocyte and its varied morphology and function.

Benign Fibrous Histiocytoma: Report of Case

2003 ◽  
Vol 4 (2) ◽  
pp. 74-79 ◽  
Author(s):  
Ümit Ertaş ◽  
M. Cemil Büyükkurt ◽  
Yasin Çiçek
Keyword(s):  
Soft Tissue ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Panoramic Radiograph ◽  
Giant Cells ◽  
Benign Fibrous Histiocytoma ◽  
Multinucleated Giant Cells ◽  
Caucasian Male ◽  
Storiform Pattern ◽  
Radiolucent Lesion

Abstract Benign fibrous histiocytoma is a rare and usually painless oral neoplasm found in adults that may affect either soft tissue or bone typically noted in their fifth decade. This case was found in a 32 year-old Caucasian male who presented with a fairly well circumscribed unilocular radiolucent lesion extending from the mandibular right first incisor to the left first premolar and reaching the inferior mandible on a panoramic radiograph. A bony window was created and the intrabony lesion was curetted. Multiple sections revealed a cellular tumor composed of uniform spindle-shaped cells arranged in a prominent whorled or storiform pattern. Scattered xanthoma cells, multinucleated giant cells, lymphocytes, and deposits of hemosiderin were noted throughout the lesional stroma. Although malignant fibrous histiocytoma of the bone is relatively well known, benign fibrous histiocytoma of the bone is very rare. Citation Ertas U, Büyükkurt MC. Benign Fibrous Histiocytoma: Report of Case. J Contemp Dent Pract 2003 May;(4)2:074-079.

Giant cell variant of malignant fibrous histiocytoma of the head and neck

1991 ◽  
Vol 105 (12) ◽  
pp. 1079-1081 ◽  
Author(s):  
Bhuvanesh Singh ◽  
Vladimir Santos ◽  
Thomas N. Guffin ◽  
Richard Alexis ◽  
Gady Har-El
Keyword(s):  
Head And Neck ◽  
Giant Cell ◽  
Malignant Fibrous Histiocytoma ◽  
Radical Surgery ◽  
Fibrous Histiocytoma ◽  
English Literature ◽  
Rare Entity ◽  
Cell Type ◽  
Cell Variant ◽  
Giant Cell Type

AbstractThe giant cell variant of malignant fibrous histiocytoma is a rare entity in head and neck. Only eight well documented cases of this type are reported in the English literature. These tumours affect the superficial and deep structures of the neck most often and are best treated with prompt radical surgery. The prognosis of the giant cell type of malignant fibrous histiocytoma is dependent on the location of the tumour, with superficial tumours having a much better outlook.

scholarly journals Giant cell variant of malignant fibrous histiocytoma of male breast: A rare case report

2015 ◽  
Vol 11 (3) ◽  
pp. 657 ◽  
Author(s):  
Ashok Kalwar ◽  
KamleshKumar Harsh ◽  
Akhil Kapoor ◽  
ShankarLal Jakhar ◽  
HarvindraSingh Kumar
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Malignant Fibrous Histiocytoma ◽  
Rare Case ◽  
Fibrous Histiocytoma ◽  
Male Breast ◽  
Rare Case Report ◽  
Cell Variant

The Ultrastructure of Malignant Fibrous Histiocytoma (Case Report)

1977 ◽  
Vol 63 (4) ◽  
pp. 387-396 ◽  
Author(s):  
Luciano Lombardi ◽  
Silvana Pilotti ◽  
Antonino Carbone ◽  
Franco Rilke
Keyword(s):  
Electron Microscopy ◽  
Stem Cells ◽  
Case Report ◽  
Soft Tissue ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Light And Electron Microscopy ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Cellular Types

A soft tissue malignant fibrous histiocytoma was studied by light and electron microscopy. The presence of fibroblast-like cells, histiocyte-like cells, undifferentiated stem cells, and xanthomatous cells was confirmed. Fibroblast- and histiocyte-like multinucleated giant cells were also observed. The observation of lysosomes in some fibroblast-like cells, the features of undifferentiated stem cells, and the presence of cells with intermediate characteristics common to xanthomatous, histiocytic, and stem cells suggest a strict relationship among these cellular types.

scholarly journals Ultrastructure of a Feline Extraskeletal Giant Cell Tumor (Malignant Fibrous Histiocytoma)

1981 ◽  
Vol 18 (6) ◽  
pp. 738-744 ◽  
Author(s):  
A. W. Confer ◽  
F. M. Enright ◽  
G. B. Beard
Keyword(s):  
Endoplasmic Reticulum ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Rough Endoplasmic Reticulum ◽  
Malignant Fibrous Histiocytoma ◽  
Mononuclear Cells ◽  
Fibrous Histiocytoma ◽  
Giant Cells ◽  
Cell Tumor ◽  
Multinucleated Giant Cells

A subcutaneous extraskeletal giant cell tumor (malignant fibrous histiocytoma) was excised repeatedly from a 9-year-old Domestic Shorthair cat. Ultrastructurally, the mass was composed of fibroblast-like, histiocyte-like, and multinucleated giant cells, and some undifferentiated cells and mononuclear cells intermediate between the fibroblast-like and histiocyte-like cells. Fibroblast-like cells were characterized by abundant well-developed rough endoplasmic reticulum, relatively smooth cytoplasmic membranes, few lysosomal structures, and finely granular chromatin. Histiocyte-like cells resembled immature macrophages. The cell membranes had many villous projections. Rough endoplasmic reticulum varied in quantity. Lysosomes were numerous. Multinucleated giant cells had characteristics of both the fibroblast-like and histiocyte-like cells. No viral particles were seen.

scholarly journals Primary giant cell malignant fibrous histiocytoma-associated with renal calculus

2014 ◽  
Vol 8 (3-4) ◽  
pp. 193 ◽  
Author(s):  
Adem Altunkol ◽  
Murat Savas ◽  
Halil Ciftci ◽  
Mehmet Gulum ◽  
Ismail Yagmur ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Giant Cell ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Soft Tissue Sarcomas ◽  
Renal Calculus ◽  
Fibrous Histiocytomas ◽  
Malignant Fibrous Histiocytomas ◽  
Visceral Organs

Malignant fibrous histiocytomas (MFH) are the most commonly seen soft tissue sarcomas in adults. It is rarely seen in some visceral organs. Kidneys are the parenchymal organs in which MFHs are most frequently seen. More than 50 cases of primary renal MFH have been reported. Among these cases, only 1 was reported as primary giant cell subtype in association with urolithiasis. This case report is the second such case with the these characteristics.

LOCAL RECURRENCES AFTER THE TREATMENT OF SOFT TISSUE MALIGNANT FIBROUS HISTIOCYTOMA (UNCLASSIFIEDPLEOMORPHIC SARCOMA) OF THE LIMBS

2019 ◽  
Vol 72 (8) ◽  
pp. 1523-1526
Author(s):  
Oleksandr O. Lytvynenko ◽  
Volodymyr F. Konovalenko ◽  
Anton Yu. Ryzhov
Keyword(s):  
Soft Tissue ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Survival Rates ◽  
Soft Tissue Sarcomas ◽  
Primary Treatment ◽  
Radical Excision ◽  
Local Recurrences ◽  
Results Of Treatment

Introduction: The treatment of patients with malignant fibrous histiocytoma as well as other soft tissue sarcomas is not sufficiently effective up to date, and has largely changed and reflects the alterations, occurred in oncology as a whole. The number of amputation decreased over the last 10-15 years. Some researchers associate the improvement of treatment outcomes with the development of combined and complex methods. The aim of the study is an improvement of the results of treatment of patients with soft tissue malignant histiocytoma on the basis of determination of factors, influencing local recurrence development. Materials and methods: The basis of our study was a comprehensive analysis of examination and treatment results of 130 patients with MFH of the soft tissue of limbs, of them in 84 patients (64.6%) the recurrences developed. The group included 45 (53.6%) males and 39 (46.4%) females. The major part of patients – 82.1% (60 patients) were older than 40 years. Results and conclusions: The number of recurrences after the treatment in general surgical facilities is 86.9%, whereas in the patients after the treatment in the specialized oncological facilities this figure is twice lower (40%). The characteristic of the medical facility where the patient receives his/her primary treatment largely affects the development of local recurrences, patients’ quality of life and overall survival rates. The surgical method remains the leading modality in the treatment of MFH of ST. Wide and radical excision of tumors in the specialized oncological facilities allows achieving better survival outcomes of the patients.

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