Synchronization of proximal intratubular pressure oscillations: evidence for interaction between nephrons

1987 ◽  
Vol 408 (5) ◽  
pp. 438-443 ◽  
Author(s):  
N. -H. Holstein-Rathlou

2003 ◽  
Vol 285 (5) ◽  
pp. F972-F989 ◽  
Author(s):  
Darren R. Oldson ◽  
Leon C. Moore ◽  
Harold E. Layton

A mathematical model previously formulated by us predicts that limit-cycle oscillations (LCO) in nephron flow are mediated by tubuloglomerular feedback (TGF) and that the LCO arise from a bifurcation that depends heavily on the feedback gain magnitude, γ, and on its relationship to a theoretically determined critical value of gain, γc. In this study, we used that model to show how sustained perturbations in proximal tubule flow, a common experimental maneuver, can initiate or terminate LCO by changing the values of γ and γc, thus changing the sign of γ - γc. This result may help explain experiments in which intratubular pressure oscillations were initiated by the sustained introduction or removal of fluid from the proximal tubule (Leyssac PP and Baumbach L. Acta Physiol Scand 117: 415–419, 1983). In addition, our model predicts that, for a range of TGF sensitivities, sustained perturbations that initiate or terminate LCO can yield substantial and abrupt changes in both distal NaCl delivery and NaCl delivery compensation, changes that may play an important role in the response to physiological challenge.







Author(s):  
Juliano Pierezan ◽  
Gabriel Maidl ◽  
Eduardo Yamao ◽  
João Paulo Silva Gonçalves ◽  
Flávio Chiesa ◽  
...  


1982 ◽  
Author(s):  
F. E. C. Culick ◽  
F. E. Marble ◽  
E. E. Zukoski


Energies ◽  
2021 ◽  
Vol 14 (6) ◽  
pp. 1609
Author(s):  
Donghyun Hwang ◽  
Kyubok Ahn

An experimental study was performed to investigate the combustion instability characteristics of swirl-stabilized combustors. A premixed gas composed of ethylene and air was burned under various flow and geometric conditions. Experiments were conducted by changing the inlet mean velocity, equivalence ratio, swirler vane angle, and combustor length. Two dynamic pressure sensors, a hot-wire anemometer, and a photomultiplier tube were installed to detect the pressure oscillations, velocity perturbations, and heat release fluctuations in the inlet and combustion chambers, respectively. An ICCD camera was used to capture the time-averaged flame structure. The objective was to understand the relationship between combustion instability and the Rayleigh criterion/the flame structure. When combustion instability occurred, the pressure oscillations were in-phase with the heat release oscillations. Even if the Rayleigh criterion between the pressure and heat release oscillations was satisfied, stable combustion with low pressure fluctuations was possible. This was explained by analyzing the dynamic flow and combustion data. The root-mean-square value of the heat release fluctuations was observed to predict the combustion instability region better than that of the inlet velocity fluctuations. The bifurcation of the flame structure was a necessary condition for combustion instability in this combustor. The results shed new insight into combustion instability in swirl-stabilized combustors.



Water ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 1888
Author(s):  
Óscar E. Coronado-Hernández ◽  
Ivan Derpich ◽  
Vicente S. Fuertes-Miquel ◽  
Jairo R. Coronado-Hernández ◽  
Gustavo Gatica

The study of draining processes without admitting air has been conducted using only steady friction formulations in the implementation of governing equations. However, this hydraulic event involves transitions from laminar to turbulent flow, and vice versa, because of the changes in water velocity. In this sense, this research improves the current mathematical model considering unsteady friction models. An experimental facility composed by a 4.36 m long methacrylate pipe was configured, and measurements of air pocket pressure oscillations were recorded. The mathematical model was performed using steady and unsteady friction models. Comparisons between measured and computed air pocket pressure patterns indicated that unsteady friction models slightly improve the results compared to steady friction models.



2019 ◽  
Vol 215 ◽  
pp. 246-250 ◽  
Author(s):  
C. Peruzzo ◽  
L. Simoni ◽  
B.A. Schrefler


Author(s):  
Corine Meuleman ◽  
Frank Willems ◽  
Rick de Lange ◽  
Bram de Jager

Surge is measured in a low-speed radial compressor with a vaned diffuser. For this system, the flow coefficient at surge is determined. This coefficient is a measure for the inducer inlet flow angle and is found to increase with increasing rotational speed. Moreover, the frequency and amplitude of the pressure oscillations during fully-developed surge are compared with results obtained with the Greitzer lumped parameter model. The measured surge frequency increases when the compressor mass flow is throttled to a smaller flow rate. Simulations show that the Greitzer model describes this relation reasonably well except for low rotational speeds. The predicted amplitude of the pressure rise oscillations is approximately two times too small when deep surge is met in the simulations. For classic surge, the agreement is worse. The amplitude is found to depend strongly on the shape of the compressor and throttle characteristic, which are not accurately known.



1998 ◽  
Vol 120 (1) ◽  
pp. 89-96 ◽  
Author(s):  
R. A. Van den Braembussche ◽  
H. Malys

A lumped parameter model to predict the high frequency pressure oscillations observed in a water brake dynamometer is presented. It explains how the measured low frequency variations of the torque are a consequence of the variation in amplitude of the high frequency flow oscillations. Based on this model, geometrical modifications were defined, aiming to suppress the oscillations while maintaining mechanical integrity of the device. An experimental verification demonstrated the validity of the model and showed a very stable operation of the modified dynamometer even at very low torque.



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