State of the antioxidant system during induction of primary generalized epileptic activity in rats

1985 ◽  
Vol 100 (5) ◽  
pp. 1489-1492 ◽  
Author(s):  
I. R. Tupeev ◽  
M. M. Bordyukov ◽  
G. N. Kryzhanovskii ◽  
E. V. Nikushkin
Keyword(s):  
Antioxidant System ◽  
Epileptic Activity ◽  
Generalized Epileptic Activity

Effect of brain extracts from rats subjected to metrazol kindling on generalized epileptic activity

1989 ◽  
Vol 107 (3) ◽  
pp. 291-294
Author(s):  
G. N. Kryzhanovskii ◽  
M. Yu. Karganov ◽  
A. A. Shandra ◽  
L. S. Godlevskii ◽  
V. K. Lutsenko ◽  
...  
Keyword(s):  
Epileptic Activity ◽  
Brain Extracts ◽  
Generalized Epileptic Activity ◽  
Metrazol Kindling

Binding of3H-diazepam with brain synaptic membranes during the development of generalized epileptic activity

1985 ◽  
Vol 100 (6) ◽  
pp. 1664-1666
Author(s):  
M. M. Bordyukov ◽  
G. N. Kryzhanovskii ◽  
E. V. Nikushkin ◽  
E. D. Bogdanova ◽  
L. L. Prilipko
Keyword(s):  
Epileptic Activity ◽  
Synaptic Membranes ◽  
Generalized Epileptic Activity

Effect of the calcium channel blocker ryodipine on focal and generalized epileptic activity

1989 ◽  
Vol 108 (5) ◽  
pp. 1562-1566
Author(s):  
M. N. Karpova ◽  
O. Yu. Pankov ◽  
R. N. Glebov ◽  
S. K. Germane ◽  
V. E. Klusha ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blocker ◽  
Channel Blocker ◽  
Epileptic Activity ◽  
Generalized Epileptic Activity

scholarly journals Effect of the compound GIZH -290 and levetiracetam on epileptic activity in rat brain structures on EEG models of bemegrid-induced seizures

2021 ◽  
pp. 14-18
Author(s):  
T. A. Voronina ◽  
S. A. Litvinova ◽  
I. G. Kovalev
Keyword(s):  
Rat Brain ◽  
Lateral Hypothalamus ◽  
Sensorimotor Cortex ◽  
Dorsal Hippocampus ◽  
Brain Structures ◽  
High Amplitude ◽  
Epileptic Activity ◽  
Paroxysmal Activity ◽  
Epileptic Discharges ◽  
Generalized Epileptic Activity

The effect of levetiracetam (a derivative of 4-phenylpyrrolidone) and its original analog, the compound GIZH-290, on primary generalized epileptic activity (EpA) in rat brain structures (sensorimotor cortex, dorsal hippocampus-CA3 field and lateral hypothalamus field) on EEG models of bemegridinduced seizures was studied. It was found that EpA, after the introduction of bemegrid, appears in 1–2 minutes in the form of prolonged generalized high-amplitude discharges and is registered within 3 hours. GIZH-290 (5 mg/kg, intraperitoneal, 15 minutes after bemegrid) causes a significant (p < 0.05) decrease in the number of epileptic discharges in the cortex and at the level of the trend in the hippocampus, which is accompanied by a decrease in the amplitude of the Epi-discharges. Levetiracetam at a dose of 200 mg / kg does not significantly change the severity of paroxysmal activity (the number of convulsive discharges and their duration) caused by bemegrid.

scholarly journals Multiple Dural Tuberculomas Presenting as Leptomeningeal Carcinomatosis

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Hasan Kocaeli ◽  
Özgür Taşkapılıoğlu ◽  
Elif Başaran ◽  
Ahmet Karaoğlu ◽  
Ahmet Bekar
Keyword(s):  
Clinical Presentation ◽  
Systemic Disease ◽  
Giant Cells ◽  
Leptomeningeal Carcinomatosis ◽  
Immunocompetent Patient ◽  
Epileptic Activity ◽  
Resonance Imaging ◽  
History Of ◽  
Magnetic Resonance Imaging Mri ◽  
Generalized Epileptic Activity

Objective and Importance. We present the rare occurrence of multiple dural-based tuberculomas mimicking leptomeningeal carcinomatosis in a young immunocompetent patient.Clinical Presentation. A 36-year-old man presented with a 2-month history of generalized epileptic activity and altered perception. Neurological examination was remarkable for bilateral Babinski's sign. Cranial magnetic resonance imaging (MRI) revealed multiple dural-based enhancing lesions with cerebral edema.Intervention. A right frontal craniotomy was performed for diagnosis. Histological examination revealed multiple confluent necrotizing and nonnecrotizing granulomas with giant cells which was consistent with tuberculosis (TB), and the patient was placed on anti-TB therapy for 24 months.Conclusion. To the best of our knowledge isolated diffuse involvement of the dura mater by TB, mimicking leptomeningeal carcinomatosis, as the sole manifestation of disease has not been reported before. Since pachymeningeal TB is rarely suspected when atypical radiological appearance is combined with the absence of systemic disease, biopsy is inevitably required for diagnosis.

The role of antioxidant system in gastroprotective action of camomile (Matricaria recutita L.) oil extract in stress induced stomach mucous ulceration

2004 ◽  
Author(s):  
V. G. Makarov ◽  
M. N. Makarova ◽  
A. E. Alexandrova ◽  
V. E. Ryzhenkov
Keyword(s):  
Antioxidant System ◽  
Matricaria Recutita ◽  
Oil Extract ◽  
Gastroprotective Action

Antioxidant System of Spirulina platensis (Nordst.) Geitler under the LED Lighting of Different Spectral Compositions

2016 ◽  
Vol 18 (2) ◽  
pp. 157-168
Author(s):  
N. V. Kozel ◽  
E. E. Manankina ◽  
Y. V. Viazau ◽  
I. A. Dremuk ◽  
S. M. Savina ◽  
...  
Keyword(s):  
Antioxidant System ◽  
Spirulina Platensis ◽  
Led Lighting

Research of enzyme activity changes in the antioxidant system and the state of NO-system in patients with colon cancer

2008 ◽  
Vol 21 (2) ◽  
pp. 255-258
Author(s):  
Sophia Kovalchuc ◽  
Andriy Revura ◽  
Bohdan Melekh ◽  
Oksana Khavrona ◽  
Yuriy Fedevych ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Enzyme Activity ◽  
Antioxidant System ◽  
The State
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