Cardiac function in premature infants with bronchopulmonary dysplasia —a 1-year follow up

1996 ◽  
Vol 155 (7) ◽  
pp. 622-622 ◽  
Author(s):  
D. Trevisanuto ◽  
O. Milanesi ◽  
F. Cantarutti ◽  
V. Zanardo
Keyword(s):  
Cardiac Function ◽  
Bronchopulmonary Dysplasia ◽  
Premature Infants

Cardiopulmonary function in premature infants with bronchopulmonary dysplasia — a 2-year follow up

1995 ◽  
Vol 154 (10) ◽  
pp. 853-858 ◽  
Author(s):  
Teresa Farstad ◽  
Frans Brockmeier ◽  
Dag Bratlid
Keyword(s):  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Cardiopulmonary Function

scholarly journals Two-Year Follow-Up Outcomes of Premature Infants Enrolled in the Phase I Trial of Mesenchymal Stem Cells Transplantation for Bronchopulmonary Dysplasia

2017 ◽  
Vol 185 ◽  
pp. 49-54.e2 ◽  
Author(s):  
So Yoon Ahn ◽  
Yun Sil Chang ◽  
Ji Hye Kim ◽  
Se In Sung ◽  
Won Soon Park
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Phase I ◽  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Phase I Trial ◽  
Stem Cells Transplantation

scholarly journals Inhaled nitric oxide (iNO) for preventing prematurity-related bronchopulmonary dysplasia (BPD): 7-year follow-up of the European Union Nitric Oxide (EUNO) trial

2021 ◽  
Vol 49 (1) ◽  
pp. 104-110
Author(s):  
Anne Greenough ◽  
Fabrice Decobert ◽  
David Field ◽  
Mikko Hallman ◽  
Helmut D. Hummler ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Oxygen Therapy ◽  
Well Being ◽  
Inhaled Nitric Oxide ◽  
Current Evidence ◽  
Home Oxygen Therapy

AbstractObjectivesMost studies of inhaled nitric oxide (iNO) for prevention of bronchopulmonary dysplasia (BPD) in premature infants have focused on short-term mortality and morbidity. Our aim was to determine the long-term effects of iNO.MethodsA 7-year follow-up was undertaken of infants entered into a multicenter, double-blind, randomized, placebo-controlled trial of iNO for prevention of BPD in premature infants born between 24 and 28 weeks plus six days of gestation. At 7 years, survival and hospital admissions since the 2-year follow-up, home oxygen therapy in the past year, therapies used in the previous month and growth assessments were determined. Questionnaires were used to compare general health, well-being, and quality of life.ResultsA total of 305 children were assessed. No deaths were reported. Rates of hospitalization for respiratory problems (6.6 vs. 10.5%, iNO and placebo group, respectively) and use of respiratory medications (6.6 vs. 9.2%) were similar. Two patients who received iNO and one who received placebo had received home oxygen therapy. There were no significant differences in any questionnaire-documented health outcomes.ConclusionsiNO for prevention of BPD in very premature infants with respiratory distress did not result in long-term benefits or adverse long-term sequelae. In the light of current evidence, routine use of iNO cannot be recommended for prevention of BPD in preterm infants.

scholarly journals Effect of airway administration of budesonide for bronchopulmonary dysplasia in premature infants: A Systematic Review and Meta-Analysis

2019 ◽  
Author(s):  
kaixu wang ◽  
Long Chen ◽  
Fang Li
Keyword(s):  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Optimal Timing ◽  
Composite Outcome ◽  
Long Term Follow Up ◽  
The Cochrane Library

Abstract Objective: Bronchopulmonary dysplasia (BPD) is one of the major challenges in preterm infants despite the therapeutic improvement. Airway administration of budesonide might be a safe and effective way. However, the optimal timing of airway administration is under determined. The meta-analysis was designed to evaluate the effectiveness and safety of early (≤1d after birth) and late (>1d after birth) airway administration of budesonide in decreasing the incidence of BPD and death as the primary outcome . Methods: PubMed, EMBASE, the Cochrane Library, China national knowledge internet (CNKI), China biology medicine disc (CBM), WANFANG data, and China Science and Technology Journal Database were searched for RCTs that compared airway administration of budesonide with controls. The meta-analysis was performed using Review Manager 5.3. Results: Airway administration of budesonide decreased the risk of BPD at 36 weeks PMA and the composite outcome of BPD or death (RR=0.64, 95%CI: 0.55~0.75 and RR=0.71, 95%CI: 0.57~0.89).Moreover, 37% and 36% reduction was observed in the incidence of BPD and the composite outcome of BPD or death in the early airway administration group (≤1d) (RR=0.63, 95%CI: 0.53~0.75 and RR=0.64, 95%CI: 0.47~0.87 ), while no difference was found in late airway administration group (>1d) (RR=0.74, 95%CI: 0.49~1.13 and RR=0.88, 95%CI: 0.64~1.21). Conclusion: early airway administration (≤1d) of budesonide reduced the incidence of BPD alone or composite outcome of death or BPD, and it is safe without increasing death as well as other short-term side effects. However, because of the small number of infants in late airway administration group and lacking of long-term follow-up, more randomized controlled trials are needed to testify for the outcomes. Keywords: Budesonide, bronchopulmonary dysplasia, premature infants, meta-analysis, airway administration.

scholarly journals The capability of chest computed tomography in the diagnosis of bronchopulmonary dysplasia outcomes in premature infants

2019 ◽  
pp. 28-32
Author(s):  
E. B. Pavlinova ◽  
I. A. Kirshina ◽  
G. A. Sakhipova ◽  
A. Yu. Gorlina ◽  
O. A. Savchenko ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Lung Tissue ◽  
Structural Changes ◽  
Late Childhood ◽  
Radiological Findings ◽  
Chest Computed Tomography ◽  
Infant Respiratory Distress Syndrome

Purpose of the study was to establish clinical and radiological features of bronchopulmonary dysplasia (BPD) outcomes in children. Materials and methods. A prospective follow-up study of 132 premature infants with infant respiratory distress syndrome (IRDS) was analyzed. BPD was developed in 66 cases. At a late childhood, clinical and radiological outcomes of the transferred conditions were diagnosed on the basis of anamnesis, clinical examination, and results of chest computed tomography (CT). Results. Clinical recovery was observed significantly more frequently in the outcome of IRDS without BPD development (69.6% versus 31.8% in the case of BPD development). In patients with BPD in the anamnesis, the odds ratio of asthma developed in the late childhood was 5.304 times higher than in children who had IRDS. The majority (62 cases, 93.9%) of children who had IRDS did not have structural changes in lung tissue according to CT (p = 0.000), 21 (31.8%) children with BPD had abnormal CT. In BPD, typical radiological findings were hypoattenuated lung areas (p = 0.020) and areas of pulmonary fibrosis (p = 0.016). Conclusion. Chest CT could be assigned to the patients with BPD in the anamnesis to assess lung tissue structural changes and diagnose outcomes of the disease.

scholarly journals SCENARIOS OF THE COURSE OF BRONCHOPULMONARY DYSPLASIA IN PREMATURE INFANTS WITH PATENT DUCTUS ARTERIOSUS IN FOLLOW-UP TO 3 YEARS

2021 ◽  
Vol 11 (4(42)) ◽  
pp. 15-20
Author(s):  
Y. Sorokolat ◽  
T. Klimenko ◽  
O. Karapetian ◽  
O. Kalutska
Keyword(s):  
Patent Ductus Arteriosus ◽  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Neonatal Period ◽  
Ductus Arteriosus ◽  
Surgical Closure ◽  
Group I ◽  
Perinatal Center ◽  
Patent Ductus

Summary. Bronchopulmonary dysplasia (BPD) is one of the most common long-term complications associated with preterm birth. The severity of BPD is associated with immaturity of a child's body, perinatal infections, and patent ductus arteriosus (PDA).The aim of the study was to identify the features of BPD in the 1st year of life of a child and in the follow- up to 3 years, depending on the condition of the ductus arteriosus.Material and methods. The observations of 146 premature infants with BPD, who were divided into groups depending on the state of the ductus arteriosus, were analyzed: Group I consisted of 58 children with BPD whose ductus arteriosus closed spontaneously in the early neonatal period; II group – 60 children with hemodynamically insignificant PDA, which remained open for 6-12 months; III group – 28 children with hemodynamically significant (HS) PDA, which required surgical closure during the stay of a child in the perinatal center. Results. There were significantly more cases of severe BPD among children of group II compared to group I: 23.3 vs. 8.6 % (p <0.01) and, accordingly, fewer cases of moderate course: 41.7 vs. 58.6 % (p <0.05) at the stage of children treatment in the perinatal center. At the age of 3 years, there were significantly more healthy children who underwent BPD in group I compared to group III: 62.5 vs. 25.9 % (p <0.01), and severe course was significantly more common in both groups II and III compared to group I: 6.8 and 7.4 % vs. 0 % (p <0.01). No significant differences in the severity of BPD at the age of 2-3 months and in the follow-up to 1 year from the date of surgical closure of HS PDA were detected. Conclusions. Sexual dimorphism was found, namely the prevalence of males among preterm infants with delayed closure of the ductus arteriosus. The presence of hemodynamic disorders connected with PDA is associated with a more severe course of BPD at the age of 3 years compared to children whose ductus arteriosus closed on its own in the early neonatal period. At the average term of surgical closure of PDA 21.5 ± 1.6 days of life, significant differences in the severity of BPD from the term of surgical closure of PDA weren`t detected.

Outpatient Management and Follow-Up of Bronchopulmonary Dysplasia

1984 ◽  
Vol 11 (1) ◽  
pp. 101-122 ◽  
Author(s):  
Beverly L. Koops ◽  
Steven H. Abman ◽  
Frank J. Accurso
Keyword(s):  
Bronchopulmonary Dysplasia ◽  
Outpatient Management

THE INCREASING OF PROBABILITY OF BRONCHOPULMONARY DYSPLASIA DEVELOPMENT IN PREMATURE INFANTS AFTER TRANSFUSION OF DONOR RED BLOOD CELLS

2014 ◽  
Vol 4 (3(13)) ◽  
pp. 74-79
Author(s):  
V.I. Pokhylko ◽  
J.O. Goncharova ◽  
G.M. Traverse ◽  
S.M. Zvirenko ◽  
O.V. Korobka
Keyword(s):  
Red Blood Cells ◽  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Blood Cells

Drainage, Irrigation and Fibrinolytic Therapy (DRIFT) in Premature Infants with Post-Haemorrhagic Ventricular Dilatation: 10-Year Follow-Up of a Randomised Controlled Trial

2019 ◽  
Author(s):  
Karen Luyt ◽  
Sally Louise Jary ◽  
Charlotte Louise Lea ◽  
Grace Johanna Young ◽  
David Edward Odd ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Premature Infants ◽  
Controlled Trial ◽  
Fibrinolytic Therapy ◽  
Ventricular Dilatation ◽  
Randomised Controlled
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