Tests of aphicides for possible systemic control of potato blight

1965 ◽  
Vol 8 (2) ◽  
pp. 98-103 ◽  
Author(s):  
A. H. McIntosh ◽  
D. W. Eveling
Keyword(s):  
Potato Blight ◽  
Systemic Control

Gamma Knife surgery combined with resection for treatment of a single brain metastasis: preliminary results

2010 ◽  
Vol 113 (Special_Supplement) ◽  
pp. 90-96 ◽  
Author(s):  
M. Yashar S. Kalani ◽  
Aristotelis S. Filippidis ◽  
Maziyar A. Kalani ◽  
Nader Sanai ◽  
David Brachman ◽  
...  
Keyword(s):  
Survival Data ◽  
Initial Treatment ◽  
Median Survival Time ◽  
Local Tumor Control ◽  
Survival Duration ◽  
Tumor Control ◽  
Local Tumor ◽  
Systemic Control ◽  
Cranial Metastasis

Object Resection and whole-brain radiation therapy (WBRT) have classically been the standard treatment for a single metastasis to the brain. The objective of this study was to evaluate the use of Gamma Knife surgery (GKS) as an alternative to WBRT in patients who had undergone resection and to evaluate patient survival and local tumor control. Methods The authors retrospectively reviewed the charts of 150 patients treated with a combination of stereotactic radiosurgery and resection of a cranial metastasis at their institution between April 1997 and September 2009. Patients who had multiple lesions or underwent both WBRT and GKS were excluded, as were patients for whom survival data beyond the initial treatment were not available. Clinical and imaging follow-up was assessed using notes from clinic visits and MR imaging studies when available. Follow-up data beyond the initial treatment and survival data were available for 68 patients. Results The study included 37 women (54.4%) and 31 men (45.6%) (mean age 60 years, range 28–89 years). In 45 patients (66.2%) there was systemic control of the primary tumor when the cranial metastasis was identified. The median duration between resection and radiosurgery was 15.5 days. The median volume of the treated cavity was 10.35 cm3 (range 0.9–45.4 cm3), and the median dose to the cavity margin was 15 Gy (range 14–30 Gy), delivered to the 50% isodose line (range 50%–76% isodose line). The patients' median preradiosurgery Karnofsky Performance Scale (KPS) score was 90 (range 40–100). During the follow-up period we identified 27 patients (39.7%) with recurrent tumor located either local or distant to the site of treatment. The median time from primary treatment of metastasis to recurrence was 10.6 months. The patients' median length of survival (interval between first treatment of cerebral metastasis and last follow-up) was 13.2 months. For the patient who died during follow-up, the median time from diagnosis of cerebral metastasis to death was 11.5 months. The median duration of survival from diagnosis of the primary cancer to last follow-up was 30.2 months. Patients with a pretreatment KPS score ≥ 90 had a median survival time of 23.2 months, and patients with a pretreatment KPS score < 90 had a median survival time of 10 months (p < 0.008). Systemic control of disease at the time of metastasis was not predictive of increased survival duration, although it did tend to improve survival. Conclusions Although the debate about the ideal form of radiation treatment after resection continues, these findings indicate that GKS combined with surgery offers comparable survival duration and local tumor control to WBRT for patients with a diagnosis of a single metastasis.

POTATO BLIGHT FORECASTING IN CUMBERLAND, 1953?57

1961 ◽  
Vol 10 (4) ◽  
pp. 127-132 ◽  
Author(s):  
H. E. Croxall ◽  
W. A. Davey ◽  
D. C. Gwynne ◽  
W. Johnson
Keyword(s):  
Potato Blight

Mutations in Phytoene Desaturase Gene in Fluridone-Resistant Hydrilla (Hydrilla verticillata) Biotypes in Florida

Weed Science ◽  
2007 ◽  
Vol 55 (5) ◽  
pp. 412-420 ◽  
Author(s):  
Atul Puri ◽  
Gregory E. MacDonald ◽  
Fredy Altpeter ◽  
William T. Haller
Keyword(s):  
Herbicide Resistance ◽  
Single Point ◽  
Hydrilla Verticillata ◽  
The United States ◽  
Phytoene Desaturase ◽  
Day Length ◽  
Single Point Mutation ◽  
Aquatic Weed ◽  
Systemic Control

Hydrilla is one of the most serious aquatic weed problems in the United States, and fluridone is the only U.S. Environment Protection Agency (USEPA)–approved herbicide that provides relatively long-term systemic control. Recently, hydrilla biotypes with varying levels of fluridone resistance have been documented in Florida. One susceptible and five fluridone-resistant biotypes of hydrilla varying in resistance levels were maintained in 950-L tanks under ambient sunlight and day-length conditions from September 2004 to September 2005 in absence of fluridone. Because fluridone is an inhibitor of the enzyme phytoene desaturase (PDS), the gene for PDS (pds) was cloned from fluridone-susceptible and -resistant hydrilla biotypes. Somatic mutations in amino acid 304 of hydrilla PDS are known to confer herbicide resistance. We determinedpdssequence from these hydrilla biotypes at planting and 12-mo after planting. Two independent mutations at the arginine 304 codon ofpdswere found in the resistant hydrilla plants. The codon usage for arginine 304 is CGT, and a single point mutation yielding either serine (AGT) or histidine (CAT) was identified in different resistant hydrilla biotypes. There were no differences at codon 304 in the PDS protein of any hydrilla biotype 12-mo after planting. Several other mutations were also found in resistantpdsalleles, though their possible role in herbicide resistance is unclear.

Pediatric Tumors: Rhabdomyosarcoma

2017 ◽  
Author(s):  
John Groundland ◽  
Sara Shaw ◽  
R L Randall
Keyword(s):  
Skeletal Muscle ◽  
Soft Tissue ◽  
Soft Tissue Sarcomas ◽  
Cytotoxic Chemotherapy ◽  
Embryonal Rhabdomyosarcoma ◽  
Pediatric Tumors ◽  
Skeletal Muscle Differentiation ◽  
Systemic Control ◽  
Therapeutic Radiation ◽  
Pleomorphic Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is a group of soft tissue sarcomas that share a common feature of primitive skeletal muscle differentiation. Three main subtypes have been characterized: embryonal, alveolar, and pleomorphic. Presentation and prognosis of RMS are highly variable, depending on anatomic location, subtype, and risk stratification. Currently, treatment centers on systemic control with cytotoxic chemotherapy and local control with surgery and/or therapeutic radiation. This review contains 3 figures, 10 tables and 50 references  Key words: alveolar rhabdomyosarcoma, embryonal rhabdomyosarcoma, pediatric soft tissue sarcoma, pleomorphic rhabdomyosarcoma, rhabdomyosarcona, t(2;13), t(1;13)

Systemic control of nodule formation by the plant N demand requires autoregulation dependent and independent mechanisms

2021 ◽  
Author(s):  
Marjorie Pervent ◽  
Ilana Lambert ◽  
Marc Tauzin ◽  
Alicia Karouani ◽  
Martha Nigg ◽  
...  
Keyword(s):  
Nitrogen Fixation ◽  
Nodule Formation ◽  
Atmospheric Nitrogen ◽  
Plant Nitrogen ◽  
Systemic Signaling ◽  
Systemic Control ◽  
Whole Plant ◽  
Strong Control ◽  
Mutant Genes ◽  
N Demand

Abstract In legumes interacting with rhizobia the formation of symbiotic organs involved in the acquisition of atmospheric nitrogen is depending of the plant nitrogen (N) demand. We used Medicago truncatula plants cultivated in split-root systems to discriminate between responses to local and systemic N signalings. We evidenced a strong control of nodule formation by systemic N-signaling but obtained no clear evidence of a local control by mineral nitrogen. Systemic signaling of the plant N demand controls numerous transcripts involved in the root transcriptome reprogramming associated to early rhizobia interaction and nodule formation. SUNN has an important role in this control but major systemic N signaling responses remained active in the sunn mutant. Genes involved in the activation of nitrogen fixation are regulated by systemic N signaling in the mutant, explaining why the hypernodulation phenotype is not associated to a higher nitrogen fixation of the whole plant. The control of the transcriptome reprogramming of nodule formation by systemic N signaling requires other pathway(s) that parallel the SUNN/CLE pathway.

Metabolomic linkage reveals functional interaction between glucose-dependent insulinotropic polypeptide and ghrelin in humans

2011 ◽  
Vol 301 (4) ◽  
pp. E608-E617 ◽  
Author(s):  
Natalia N. Rudovich ◽  
Victoria J. Nikiforova ◽  
Baerbel Otto ◽  
Olga Pivovarova ◽  
Özlem Gögebakan ◽  
...  
Keyword(s):  
Molecular Mechanisms ◽  
Gastrointestinal Hormones ◽  
Plasma Metabolites ◽  
Long Chain Fatty Acids ◽  
Long Chain Fatty Acid ◽  
Insulin Levels ◽  
Systemic Control ◽  
Combining Data ◽  
Obese Subjects ◽  
Long Chain

The gastric peptide ghrelin promotes energy storage, appetite, and food intake. Nutrient intake strongly suppresses circulating ghrelin via molecular mechanisms possibly involving insulin and gastrointestinal hormones. On the basis of the growing evidence that glucose-dependent insulinotropic polypeptide (GIP) is involved in the control of fuel metabolism, we hypothesized that GIP and/or insulin, directly or via changes in plasma metabolites, might affect circulating ghrelin. Fourteen obese subjects were infused with GIP (2.0 pmol·kg−1·min−1) or placebo in the fasting state during either euglycemic hyperinsulinemic (EC) or hyperglycemic hyperinsulinemic clamps (HC). Apart from analysis of plasma ghrelin and insulin levels, GC-TOF/MS analysis was applied to create a hormone-metabolite network for each experiment. The GIP and insulin effects on circulating ghrelin were analyzed within the framework of those networks. In the HC, ghrelin levels decreased in the absence (19.2% vs. baseline, P = 0.028) as well as in the presence of GIP (33.8%, P = 0.018). Ghrelin levels were significantly lower during HC with GIP than with placebo, despite insulin levels not differing significantly. In the GIP network combining data on GIP-infusion, EC+GIP and HC+GIP experiments, ghrelin was integrated into hormone-metabolite networks through a connection to a group of long-chain fatty acids. In contrast, ghrelin was excluded from the network of experiments without GIP. GIP decreased circulating ghrelin and might have affected the ghrelin system via modification of long-chain fatty acid pools. These observations were independent of insulin and offer potential mechanistic underpinnings for the involvement of GIP in systemic control of energy metabolism.

scholarly journals The effectiveness of a new biological product Spud on the basis of Bacillus subtilis in the cultivation of potatoes

2019 ◽  
pp. 8-14
Author(s):  
Marina Konstantinovna Derevyagina ◽  
Svetlana Viktorovna Vasilyeva ◽  
Grigory Leonidovich Belov ◽  
Vladimir Nikolaevich Zeyruk ◽  
Irina Igorevna Novikova
Keyword(s):  
Late Blight ◽  
Disease Development ◽  
Dry Rot ◽  
Potato Blight ◽  
Potato Plants ◽  
Moderate Disease ◽  
Rhizoctonia Disease ◽  
The Impact ◽  
Fungistatic Effect ◽  
New Crop

It is shown the efficiency of the application of preparative forms (dry and liquid) of Kartofin during the growing season 2016-2018 years against major diseases of potatoes and the impact on the growth and development of culture. Biopreparation possesses high fungistatic effect, protecting potato plants against rhizoctonia disease, potato blight and late blight under field conditions and tubers of the new crop from dry rot. In years of low and moderate disease development, the effectiveness of the studied Potato biopreparation on the Sante variety was at the level of the reference chemical variant, equally reducing the distribution and degree of disease development. In the years of epiphytotic disease development fungistatic effect of the biopreparation was inferior in efficiency to chemical fungicides, but had a significant protective effect compared to the control, reducing the distribution of rhizoctonia disease by 22.5%, potato blightby 20.7%, late blight by 12.8% on average. The results of tuberous analyses after harvesting showed a decrease in the percentage of tuber damage by dry rot in variants with Kartofin (1.7 and 1.4%). The yield of the standard potatoes after application of Kartofin was slightly higher than in the control – by  5.1–7.7%.

scholarly journals The importance and the role of forensics of mobile

2012 ◽  
Vol 25 (2) ◽  
pp. 121-136 ◽  
Author(s):  
Zaklina Spalevic ◽  
Zeljko Bjelajac ◽  
Marko Caric
Keyword(s):  
Digital Forensics ◽  
Technological Development ◽  
Human Life ◽  
High Technology ◽  
Computer Forensics ◽  
System Support ◽  
Electronic Networks ◽  
Systemic Control

Scientific-technological development, along with initiating integrative forces that offer improvement of the quality of human life, concurrently created prerequisites for individuals to exploit certain innovations for performing criminal activities. Modern criminals wander through electronic networks, and assisted by high technology, perform a variety of criminal acts and ?launder? large sums of money. Computer forensics is a technological, systemic control of the computer system and its content for the purpose of gathering evidence of a criminal act or other abuse that it has been used for. Digital forensics requires particular expertise that goes beyond traditional data collection, as well as employment of techniques available to the final user or system support personnel. In this context, this article examines principles, methods and procedures in mobile device investigation, which nowadays represent a multifunctional, powerful computer weapon, and considers the necessity to update concrete procedures in accordance with the development and growth of IT.

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