The functional relationship of the longitudinal and circular muscle of the guinea-pig uterus and human fallopian tube

1975 ◽  
Vol 144 (1) ◽  
pp. 319-329
Author(s):  
W. J. Hall ◽  
Catherine M. Ryan
1977 ◽  
Vol 55 (5) ◽  
pp. 1102-1106
Author(s):  
K. Rajkumar ◽  
P. L. Sharma

The affinity of phenylephrine (pD2 value) and KB value for phentolamine for the α-adrenergic receptors of circular and longitudinal muscle of isthmus of rabbit fallopian tube and rabbit aorta have been estimated. The affinity of both phenylephrine and phentolamine was significantly more for the α adrenoceptors of the longitudinal muscle of isthmus of rabbit fallopian tube and rabbit aorta than circular muscle of isthmus of fallopian tube.The results of this investigation suggest that α adrenoceptors of circular muscle of isthmus are atypical. If this holds good for the human fallopian tube, the development of selective α-adrenergic-receptor agonists and antagonists may be of potential practical application for the control of fertility.


1986 ◽  
Vol 251 (6) ◽  
pp. R1126-R1136
Author(s):  
M. Nozaki ◽  
Y. Ito

The shapes and frequencies of spontaneous contractions of circular muscle strips of the human oviduct differ during the menstrual cycles. However, under given conditions, the frequency and amplitude of the contractions were continuously reduced during perfusion with Krebs solution. In the presence of prostaglandin (PG) synthesis inhibitors or an antagonist, a gradual and continuous reduction was no longer observed, and low concentrations (10(-15)-10(-10) M) of PGE2 markedly suppressed the amplitude and frequency of the spontaneous contractions. The highest sensitivity of smooth muscle cells to PGE2 was observed during the periovulatory phases. Spontaneous prepotentials followed by slow waves were observed, and the latter potentials triggered contraction of the tissue. PGE2 (10(-14)-10(-12) M) inhibited, and PGF2 alpha (10(-9)-10(-7) M) enhanced the frequency of these slow waves. The amount of PGE series released from the tissues was twice of PGF series. These results suggest that endogenous prostaglandins play a physiological role in the transport of ovum in the human fallopian tube as a result of the regulation of spontaneous membrane and mechanical activities.


1999 ◽  
Vol 26 (3) ◽  
pp. 160-165 ◽  
Author(s):  
Zell A. Mcgee ◽  
Robert L. Jensen ◽  
Christopher M. Clemens ◽  
David Taylor-Robinson ◽  
Alan P. Johnson ◽  
...  

1979 ◽  
Author(s):  
C Cierniewski ◽  
T Krajewski ◽  
E Janiak

Various studies on the interaction of immobilized mammalian fibrinogen and fibrin monomers with some fibrinogen derivatives demonstrated the presence of two sets of polymerization sites in the mammalian fibrinogen molecule. We obtained the same results while investigating the fibrinogen molecules of other classes of vertebrates /Pisces. Amphibia. Aves/. Despite significant differences among their subunit structures, all of them contain polymerization sites homologous to mammalian counterparts. Moreover, due to great functional similarity, fibrinogen or fibrin monomers of the analyzed species of Pisces. Amphibia. Aves and Mammalia interacted in a specific way with immobilized pig fibrin monomers or fibrinogen, respectively. Using these pig affinity adsorbents, fibrinogen and fibrin monomers of different vertebrates were isolated directly from plasma and analyzed by SDS polyacrylamide gel electrophoresis. Polypeptide compositions of eluted proteins were identical to those obtained for corresponding fibrinogen preparations isolated by cold-ethanol fractionation method. It appears to indicate that the nature of polymerization sites in vertebrate fibrinogens is alike.


1969 ◽  
Vol 61 (1_Suppl) ◽  
pp. S80 ◽  
Author(s):  
Hubertus A. van Leusden

2000 ◽  
Vol 15 (7) ◽  
pp. 1597-1603 ◽  
Author(s):  
Hisao Ando ◽  
Miya Kobayashi ◽  
Shigeru Toda ◽  
Fumitaka Kikkawa ◽  
Tetsuo Masahashi ◽  
...  

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