Total body and regional bone mineral content in hemodialysis patients

1994 ◽  
Vol 8 (1) ◽  
pp. 41-46 ◽  
Author(s):  
Satoshi Hagiwara ◽  
Hideyuki Aratani ◽  
Takami Miki ◽  
Yoshiki Nishizawa ◽  
Terue Okamura ◽  
...  
Metabolism ◽  
1994 ◽  
Vol 43 (2) ◽  
pp. 263-266 ◽  
Author(s):  
H. Rico ◽  
M. Revilla ◽  
L.F. Villa ◽  
M.Alvarez del Buergo ◽  
D. Ruiz-Contreras

Author(s):  
Annie M. Constable ◽  
Josie E. Porter ◽  
Danielle Benger ◽  
Dimitris Vlachopoulos ◽  
Alan R. Barker ◽  
...  

Purpose: Moderate-to-vigorous physical activity (MVPA) positively influences bone mineral content (BMC) in prepubertal children, but it is unknown whether this relationship is partially mediated by free leptin index. The aim of this study was to examine whether the relationship between MVPA and total body less head (TBLH) BMC is mediated or moderated by free leptin index in prepubertal children. Methods: We performed a cross-sectional analysis on 401 children (194 girls) from baseline examinations of the Physical Activity and Nutrition in Childhood Study. We applied the four-way decomposition mediation analysis method to assess whether free leptin index, measured from fasted blood samples, mediated the relationship between accelerometer-measured MVPA and TBLH BMC measured by dual-energy X-ray absorptiometry. Results: MVPA had a positive controlled direct effect on TBLH BMC in girls and boys (β = 0.010 to 0.011, p < 0.05). There was no mediation or interaction between MVPA, free leptin index and TBLH BMC in girls or boys (β = −0.000 to 0.001, p > 0.05). Conclusion: Our study indicates that MVPA positively influences TBLH BMC through pathways not related to free leptin index in predominantly normal-weight prepubertal children, likely primarily through mechanical loading. The relationships between MVPA, free leptin index and TBLH BMC may be influenced by other factors such as pubertal status and adiposity, so it is unknown whether these observations extend to overweight and obese children at different stages of puberty.


2019 ◽  
Vol 316 (1) ◽  
pp. R59-R67
Author(s):  
Tamara Hew-Butler ◽  
Kailyn Angelakos ◽  
Joshua Szczepanski

The purpose of this study was to assess relationships between plasma sodium concentration ([Na+]) and bone mineral content (BMC) after an acute sodium load plus treadmill walking and then quantify the amount of sodium the dual energy X-ray absorptiometry (DXA) scan could detect. The primary study was a single-blind randomized control crossover trial under two conditions: ingestion of six flour tablets (placebo trial) or six 1-g NaCl tablets (salt intervention trial). The tablets were ingested after baseline blood and urine collection followed immediately by the DXA scan. After 60 min of rest, a 45-min treadmill walk was conducted. Immediately postexercise, blood and urine were collected and the DXA scan was repeated. Main outcomes included changes (∆: post minus pre) in plasma [Na+] and BMC. Additionally, six 1-g NaCl tablets were superimposed over a DXA spine phantom for separate quantification of sodium as BMC. Fourteen subjects completed the primary study. Two-way repeated measures ANOVA tests revealed significant interaction ( F = 13.06; P = 0.0007), condition ( F = 21.88; P < 0.001), and time ( F = 6.51; P = 0.014) effects in plasma [Na+]. A significant condition ( F = 6.46; P = 0.014) effect was also noted in urine [Na+]. Total body BMC∆ was negatively correlated with plasma [Na+]∆ ( r = −0.43; P = 0.02) and urine [Na+]∆ ( r = −0.47; P = 0.01). Total body BMC∆ in the salt intervention trial [−5.5 (27) g] closely approximated the amount of NaCl ingested and subsequently absorbed into the bloodstream. The DXA scan quantified 67% of NaCl tablets as BMC in spine phantom analyses. Total body BMC∆ was negatively related to plasma and urine [Na+]∆ after treadmill walking. Reductions in total body BMC closely approximated the amount of NaCl ingested (~6 g). The DXA scan quantified NaCl as BMC.


1993 ◽  
Vol 26 (11) ◽  
pp. 1691-1696
Author(s):  
Yoshio Nomura ◽  
Hiroaki Mizoguchi ◽  
Masayuki Nakagawa ◽  
Nobuyoshi Nasu ◽  
Tsutomu Nishida ◽  
...  

1992 ◽  
Vol 24 (Supplement) ◽  
pp. S11 ◽  
Author(s):  
P. C. Fehling ◽  
R. J. Stillman ◽  
K. A. Boileau ◽  
M. H. Slaughter ◽  
J. L. Clasey ◽  
...  

1991 ◽  
Vol 142 (3) ◽  
pp. 227-230 ◽  
Author(s):  
E.R. Hernandez ◽  
M. Revilla ◽  
H. Rico

1997 ◽  
Vol 61 (2) ◽  
pp. 134-138 ◽  
Author(s):  
M. Revilla ◽  
L. F. Villa ◽  
A. Sánchez-Atrio ◽  
E. R. Hernández ◽  
H. Rico

Sign in / Sign up

Export Citation Format

Share Document