Active oxygen radical scavenging ability of water-soluble fullerenols

1997 ◽  
Vol 42 (9) ◽  
pp. 748-752 ◽  
Author(s):  
Dayong Sun ◽  
Yanshi Zhu ◽  
Ziyang Liu ◽  
Guizhen Liu ◽  
Xinghua Guo ◽  
...  
Keyword(s):  
Radical Scavenging ◽  
Oxygen Radical ◽  
Active Oxygen ◽  
Water Soluble ◽  
Radical Scavenging Ability

Synthesis of water-soluble cystine C60 derivative with catalyst and its active oxygen radical scavenging ability

2007 ◽  
Vol 18 (1) ◽  
pp. 51-54 ◽  
Author(s):  
Zhen Hu ◽  
Wen Chao Guan ◽  
Xiang Ying Tang ◽  
Li Zhen Huang ◽  
Hong Xu
Keyword(s):  
Radical Scavenging ◽  
Oxygen Radical ◽  
Active Oxygen ◽  
Water Soluble ◽  
Radical Scavenging Ability

scholarly journals Radical Scavenging Ability by ESR Spin Trapping and Oxygen Radical Absorbance Capacity of Hot Water Extracts from Mushrooms

2013 ◽  
Vol 60 (4) ◽  
pp. 173-178 ◽  
Author(s):  
Tomomi Kanno ◽  
Shouei Kawamura ◽  
Etsuko Harada ◽  
Hiromi Kameya ◽  
Mitsuko Ukai ◽  
...  
Keyword(s):  
Radical Scavenging ◽  
Spin Trapping ◽  
Oxygen Radical ◽  
Hot Water ◽  
Oxygen Radical Absorbance Capacity ◽  
Water Extracts ◽  
Esr Spin Trapping ◽  
Radical Scavenging Ability

Improved antioxidative performance of a water-soluble copper nanoparticle@fullerenol composite formed via photochemical reduction

2021 ◽  
Vol 45 (37) ◽  
pp. 17660-17666
Author(s):  
Jie Wan ◽  
Jiaxin Ma ◽  
Yuyuan Zhang ◽  
Yuxuan Xia ◽  
Liu Hong ◽  
...  
Keyword(s):  
Copper Nanoparticles ◽  
Radical Scavenging ◽  
Water Soluble ◽  
Copper Nanoparticle ◽  
Photochemical Reduction ◽  
Radical Scavenging Ability

We synthesized a water-soluble nanocomposite consisting of ultrasmall copper nanoparticles and fullerenol, which showed excellent radical scavenging ability (IC50 = 14.5 μg mL−1).

Seasonal variations of oxygen radical scavenging ability in rosemary leaf extract

2018 ◽  
Vol 245 ◽  
pp. 270-274 ◽  
Author(s):  
Yoshimi Sueishi ◽  
Misato Sue ◽  
Hiroaki Masamoto
Keyword(s):  
Seasonal Variations ◽  
Leaf Extract ◽  
Radical Scavenging ◽  
Oxygen Radical ◽  
Radical Scavenging Ability

Is the Oxygen Radical Absorbance Capacity (ORAC) Method a Peroxyl-radical Scavenging Assay?

2010 ◽  
Vol 224 (06) ◽  
pp. 921-928 ◽  
Author(s):  
Yoshimi Sueishi ◽  
Daisuke Yoshioka ◽  
Shigeru Oowada ◽  
Nobuyuki Endoh ◽  
Shunji Kohri ◽  
...  
Keyword(s):  
Peroxyl Radical ◽  
Radical Scavenging Activity ◽  
Aqueous Media ◽  
Radical Scavenging ◽  
Spin Trapping ◽  
Oxygen Radical ◽  
Water Soluble ◽  
Oxygen Radical Absorbance Capacity ◽  
Peroxyl Radicals ◽  
Radical Initiator

AbstractThe oxygen radical absorbance capacity (ORAC) method employs a water soluble azo-radical initiator, AAPH (2,2’-azobis(2-amidinopropane) dihydrochloride) as a free radical generator, by which the fluorescent probe fluorescein is damaged to result in the loss of fluorescence. Antioxidants can protect the probe from the damage and the degree of protection is quantified. Because AAPH has been used as a lipid-peroxidation reagent, “oxygen radical” in ORAC is generally accepted as peroxyl radicals; however, in the present spin trapping experiments using a newly developed spin trap, CYPMPO, there was no indication of peroxyl-radical formation in AAPH decomposition in aqueous media. These spin trapping studies demonstrated that alkoxyl (RO·) radical adduct was the sole product of AAPH decomposition. In contrast, alkyl-peroxyl (ROO·) radical was spin-trapped during the decomposition of a lipid soluble azo-radical initiator AIBN (azobis(isobutyronitrile)) in non-aqueous media. We speculate that alkyl-peroxyl radicals are short-lived in water, rapidly converted into alkoxyl radicals. Although the possibility that ORAC method monitors peroxyl-radical scavenging activity cannot be completely eliminated, spin trapping evidence strongly indicates that ORAC method is a scavenging capacity assay for alkoxyl radicals.

PHARMACOGNOSTIC, ANTIOXIDANT AND ACUTE TOXICITY STUDY OF Ficus sycomorus (Linn) (Moraceae) ROOT AND STEM BARK

2020 ◽  
Vol 4 (2) ◽  
pp. 605-614
Author(s):  
Murtala M. Namadina ◽  
H. Haruna ◽  
U. Sanusi
Keyword(s):  
Acute Toxicity ◽  
Radical Scavenging ◽  
Stem Bark ◽  
The Body ◽  
Toxicity Study ◽  
Bark Extract ◽  
Root Extract ◽  
Acute Toxicity Study ◽  
Radical Scavenging Ability ◽  
Phytochemical Components

Most of biochemical reactions in the body generates Reactive Oxygen Species (ROS), which are involved in the pathogenesis of oxidative stress-related disorders like diabetes, nephrotoxicity, cancer, cardiovascular disorders, inflammation and neurological disorders when they attack biochemical molecules like proteins, lipids and nucleic acid. Antioxidants are used to protect the cells or tissues against potential attack by ROS. Most medicinal plants possess a rich source of antioxidants such as flavonoids, phenols, tannins, alkaloids among others. These phytochemicals are currently pursued as an alternative and complimentary drug. In this study, phytochemical components, antioxidant and acute toxicity study of the methanol extract of stem bark and root of F. sycomorus were carried out using standard methods. Findings from this study revealed the presence of some diagnostic microscopical features such as calcium oxalate, starch, gum/mucilage, lignin, Aleurone grain, suberized/Cuticular cell wall and inulin but calcium carbonate was absent in stem bark but present in the powdered root. Quantitative physical constants include moisture contents (6.40% and 7.82%), ash value (7.20% and 9.30 %) in stem bark and root respectively. Carbohydrates, alkaloid, flavonoids, saponins, tannins, glycoside, steroid, triterpenes and phenols were present in all the extracts. They were found to exhibit potent 1,1,-diphenyl 2-picryl hydrazyl (DPPH) free scavenging activity. The DPPH radical scavenging ability of the extracts showed the following trend Ascorbic acid < stem bark extract˃ root extract. The LD50 of the methanolic stem bark and root extracts were found to be greater than 5000 mg /kg and is considered safe for use. Nonetheless, further

Sign in / Sign up

Export Citation Format

Share Document