Vitamin D receptor polymorphisms, bone ultrasound and mineral density in post-menopausal women

2005 ◽  
Vol 17 (2) ◽  
pp. 121-124 ◽  
Author(s):  
Katerina Zajickova ◽  
Ivana Zofkova ◽  
Martin Hill
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Mineral Density ◽  
Bone Ultrasound ◽  
Menopausal Women ◽  
Post Menopausal

Association between vitamin D and bone mineral density in post-menopausal women with metabolic syndrome

2015 ◽  
Vol 22 (1) ◽  
pp. 7-14
Author(s):  
Jolanta Dadonienė ◽  
Alma Čypienė ◽  
Egidija Rinkūnienė ◽  
Jolita Badarienė ◽  
Jelizaveta Burca ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Metabolic Syndrome ◽  
Vitamin D ◽  
Bone Mineral ◽  
Density Lipoprotein ◽  
Serum Glucose ◽  
Mineral Density ◽  
Normal Bone Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal

Background. The aim of this study was to identify the relation between vitamin D level and mineral bone density in post-menopausal women with metabolic syndrome. Materials and methods. This study included 100 post-menopausal women at age between 50 and 65 with metabolic syndrome. All participants underwent anthropometric measurements. Laboratory tests were performed to determine lipid profile, serum glucose, creatinine, C-reactive protein, vitamin D (25(OH) D), ionized calcium concentration and urine albumin / creatinine ratio. Bone mineral density of the lumbar spine (L1– L4) and total hip was measured by dual-energy X-ray absorptiometry. Results. According to the vitamin D concentration level in the blood all women were divided into four groups: the average failure was observed in 57%, mild failure in 33%, severe failure in 5%; and only 5% of women had normal vitamin levels. The mean 25(OH) D level was 47.40  ±  16.91  nmol/l. According to bone densitometry we found that 77% of all participants had normal bone mineral density, 22% had osteopenia and 5% were diagnosed with osteoporosis. No correlation was found between bone mineral density and 25(OH)  D levels. We found a weak positive correlation between high density lipoprotein cholesterol and 25(OH) D (r = 0.3, p 

scholarly journals Raloxifene administration in post-menopausal women with osteoporosis: effect of different BsmI vitamin D receptor genotypes

2003 ◽  
Vol 18 (1) ◽  
pp. 192-198 ◽  
Author(s):  
S. Palomba ◽  
F. G. Numis ◽  
G. Mossetti ◽  
D. Rendina ◽  
P. Vuotto ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Menopausal Women ◽  
Post Menopausal

Does vitamin D receptor polymorphism influence response of bone to brisk walking in post-menopausal women?

1996 ◽  
Vol 6 (S1) ◽  
pp. 138-138
Author(s):  
I. Tsuritani ◽  
K. Brooke-Wavell ◽  
S. S. Mastana ◽  
P. R. M. Jones ◽  
A. E. Hardman ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Brisk Walking ◽  
Menopausal Women ◽  
Vitamin D Receptor Polymorphism ◽  
Post Menopausal ◽  
Receptor Polymorphism

Distinct association of gene polymorphisms of estrogen receptor and vitamin D receptor with lumbar spondylosis in post-menopausal women

2005 ◽  
Vol 15 (10) ◽  
pp. 1521-1528 ◽  
Author(s):  
Yu Koshizuka ◽  
Naoshi Ogata ◽  
Masataka Shiraki ◽  
Takayuki Hosoi ◽  
Atsushi Seichi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Estrogen Receptor ◽  
Vitamin D Receptor ◽  
Gene Polymorphisms ◽  
Lumbar Spondylosis ◽  
Menopausal Women ◽  
Post Menopausal

Association of serum vitamin D with bone mineral density and breastfeeding in post-menopausal women from a Mexican rural community

2016 ◽  
Author(s):  
Nicole Ellis-Infante ◽  
Fernando Blanco-Rodriguez ◽  
Victor Lopez-Rivas ◽  
Sherlin May-Kim ◽  
Charlotte Pickett ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Mineral ◽  
Rural Community ◽  
Serum Vitamin ◽  
Mineral Density ◽  
Serum Vitamin D ◽  
Menopausal Women ◽  
Post Menopausal

Do Vitamin D Receptor Gene Polymorphisms Correlate With Osteoporosis in Post- Menopausal Women?

2015 ◽  
Vol 04 (04) ◽  
Author(s):  
Reza Najafipour Aida Alesmail ◽  
Homayoun Sheikholeslami ◽  
Safar Ali Alizadeh ◽  
Zahra Rashvand Amir Mohammad
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Gene Polymorphisms ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Menopausal Women ◽  
Receptor Gene Polymorphisms ◽  
Post Menopausal

scholarly journals Vitamin D Receptor Gene Variants Susceptible to Osteoporosis in Arab Post-Menopausal Women

2021 ◽  
Vol 43 (3) ◽  
pp. 1325-1334
Author(s):  
Mohammed. G. A. Ansari ◽  
Abdul Khader Mohammed ◽  
Kaiser A. Wani ◽  
Syed D. Hussain ◽  
Abdullah M. Alnaami ◽  
...  
Keyword(s):  
Vitamin D ◽  
Postmenopausal Women ◽  
Vitamin D Receptor ◽  
Elderly Women ◽  
Gene Variants ◽  
Mineral Density ◽  
Vdr Gene ◽  
Post Menopausal Osteoporosis ◽  
Increased Risk ◽  
Post Menopausal

Post-menopausal osteoporosis (PMO) is a multifactorial bone disorder in elderly women. Various vitamin D receptor (VDR) gene variants have been studied and associated with osteoporosis in other populations, but not in a homogenous Arab ethnic group. Herein, the current study explores the association between VDR polymorphisms and susceptibility to osteoporosis in Saudi postmenopausal women. In total, 600 Saudi postmenopausal women (N = 300 osteoporosis; N = 300 control) were genotyped for VDR gene variants (rs7975232, rs1544410, rs731236) using TaqMan® SNP genotyping assays. Bone mineral density (BMD) for the lumbar spine and femur was assessed using dual-energy X-ray absorptiometry (DEXA). The heterozygous frequency distributions AC of rs7975232, CT of rs1544410, and AG of rs731236 were significantly higher in the osteoporosis group than controls (p < 0.05). Heterozygous AC of rs7975232 (1.6; 95% CI 1.1–2.3; p < 0.023), CT of rs1544410 (1.6; 95% CI 1.1–2.4; p < 0.022), and AG of rs731236 (1.6; 95% CI 1.1–2.4; p < 0.024) were significantly associated with increased risk of osteoporosis, independent of age and BMI. In conclusion, VDR gene variants rs7975232, rs1544410, rs731236 had a significant effect on BMD and were associated with osteoporosis risk in Saudi postmenopausal women.

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