scholarly journals Dietary inflammatory index and type 2 diabetes risk in a prospective cohort of 70,991 women followed for 20 years: the mediating role of BMI

Diabetologia ◽  
2019 ◽  
Vol 62 (12) ◽  
pp. 2222-2232 ◽  
Author(s):  
Nasser Laouali ◽  
Francesca Romana Mancini ◽  
Mariem Hajji-Louati ◽  
Douae El Fatouhi ◽  
Beverley Balkau ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Prospective Cohort ◽  
Diabetes Risk ◽  
Dietary Inflammatory Index ◽  
Inflammatory Index ◽  
Mediating Role

scholarly journals A Selective Role of Dietary Anthocyanins and Flavan-3-ols in Reducing the Risk of Type 2 Diabetes Mellitus: A Review of Recent Evidence

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 841 ◽  
Author(s):  
Britt Burton-Freeman ◽  
Michał Brzeziński ◽  
Eunyoung Park ◽  
Amandeep Sandhu ◽  
Di Xiao ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Risk Reduction ◽  
Critical Role ◽  
Glucose Absorption ◽  
Diabetes Risk ◽  
Fiber Plant

Type 2 diabetes mellitus (T2DM) is the most common form of DM and its prevalence is increasing worldwide. Because it is a progressive disease, prevention, early detection and disease course modification are possible. Diet plays a critical role in reducing T2DM risk. Therapeutic dietary approaches routinely recommend diets high in plant foods (i.e., vegetables, fruits, whole-grains). In addition to essential micronutrients and fiber, plant-based diets contain a wide-variety of polyphenols, specifically flavonoid compounds. Evidence suggests that flavonoids may confer specific benefits for T2DM risk reduction through pathways influencing glucose absorption and insulin sensitivity and/or secretion. The present review assesses the relationship between dietary flavonoids and diabetes risk reduction reviewing current epidemiology and clinical research. Collectively, the research indicates that certain flavonoids, explicitly anthocyanins and flavan-3-ols and foods rich in these compounds, may have an important role in dietary algorithms aimed to address diabetes risk factors and the development of T2DM.

scholarly journals Diabetes inHFEHemochromatosis

2017 ◽  
Vol 2017 ◽  
pp. 1-16 ◽  
Author(s):  
James C. Barton ◽  
Ronald T. Acton
Keyword(s):  
Type 2 Diabetes ◽  
Serum Ferritin ◽  
Iron Homeostasis ◽  
Reference Range ◽  
Clinical Manifestations ◽  
Diabetes Type 2 ◽  
Diabetes Risk ◽  
European Descent

Diabetes in whites of European descent with hemochromatosis was first attributed to pancreatic siderosis. Later observations revealed that the pathogenesis of diabetes inHFEhemochromatosis is multifactorial and its clinical manifestations are heterogeneous. Increased type 2 diabetes risk inHFEhemochromatosis is associated with one or more factors, including abnormal iron homeostasis and iron overload, decreased insulin secretion, cirrhosis, diabetes in first-degree relatives, increased body mass index, insulin resistance, and metabolic syndrome. In p.C282Y homozygotes, serum ferritin, usually elevated at hemochromatosis diagnosis, largely reflects body iron stores but not diabetes risk. In persons with diabetes type 2 without hemochromatosis diagnoses, serum ferritin levels are higher than those of persons without diabetes, but most values are within the reference range. Phlebotomy therapy to achieve iron depletion does not improve diabetes control in all persons withHFEhemochromatosis. The prevalence of type 2 diabetes diagnosed today in whites of European descent with and withoutHFEhemochromatosis is similar. Routine iron phenotyping orHFEgenotyping of patients with type 2 diabetes is not recommended. Herein, we review diabetes inHFEhemochromatosis and the role of iron in diabetes pathogenesis in whites of European descent with and withoutHFEhemochromatosis.

Relationship style and glycaemic control in women with type 2 diabetes: The mediating role of psychological distress

2018 ◽  
Vol 34 (3) ◽  
pp. 462-467 ◽  
Author(s):  
Omar Braizat ◽  
Richard Feinn ◽  
Gina Abbott ◽  
Julie Wagner
Keyword(s):  
Type 2 Diabetes ◽  
Psychological Distress ◽  
Glycaemic Control ◽  
Mediating Role ◽  
Relationship Style

scholarly journals Association of Lifecourse Socioeconomic Status with Chronic Inflammation and Type 2 Diabetes Risk: The Whitehall II Prospective Cohort Study

PLoS Medicine ◽  
2013 ◽  
Vol 10 (7) ◽  
pp. e1001479 ◽  
Author(s):  
Silvia Stringhini ◽  
G. David Batty ◽  
Pascal Bovet ◽  
Martin J. Shipley ◽  
Michael G. Marmot ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Socioeconomic Status ◽  
Cohort Study ◽  
Chronic Inflammation ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Diabetes Risk

scholarly journals Relationship Between Social Capital and Depressive Symptoms Among Type 2 Diabetes Mellitus Patients in Northwest China: A Mediating Role of Sleep Quality

2021 ◽  
Vol 12 ◽  
Author(s):  
Liqun Wang ◽  
Jiangping Li ◽  
Yuqi Dang ◽  
Haiyu Ma ◽  
Yang Niu
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Depressive Symptoms ◽  
Sleep Quality ◽  
Northwest China ◽  
Mediating Role ◽  
The Relationship

Objective: There are few studies about the relationship between social capital (SC) and depression among type 2 diabetes mellitus (T2DM) patients, and the mechanism explaining how SC leads to decreased depression is unclear. The current study aims to explore the relationship between SC and depressive symptoms among the T2DM patients in northwest China, with a particular focus on the mediating role of sleep quality.Methods: A cross-sectional study of 1,761 T2DM patients from Ningxia Province was conducted. The Center for Epidemiological Survey Depression Scale (CES-D) and self-report sleep quality questionnaire coupled with the SC scales were administered during the face-to-face survey. The Bootstrap methods PROCESS program is employed to test the mediation model.Results: The prevalence of depressive symptoms among T2DM patients was 24.8%. After controlling for covariates, the SC (r = −0.23, p < 0.001) was negatively correlated with CES-D score; the sleep quality was also negatively correlated with CES-D score (r = −0.31, p < 0.001); and the SC was positively correlated with sleep quality (r = 0.10, p < 0.001). Logistic regression analysis showed that SC was inversely related to the risk of depressive symptoms. Meanwhile, sleep quality was negatively associated with depressive symptoms. Sleep quality has mediated the relationship between SC and depressive symptoms among T2DM patients (explaining 12.6% of the total variance).Conclusions: We elucidated how SC interacted with depressive symptoms through the mediation pathway of sleep quality using a representative sample of the Chinese diabetes patients. The findings indicate that the improvement of SC and sleep quality may help in maintaining mental health among T2DM patients. Hence, clinicians can suggest that patients communicate more with others to improve the SC and, in turn, maintain their health.

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