scholarly journals Multiscale thermal and thermo-structural optimization of three-dimensional lattice structures

2021 ◽  
Vol 65 (1) ◽  
Author(s):  
Chikwesiri Imediegwu ◽  
Ryan Murphy ◽  
Robert Hewson ◽  
Matthew Santer
Keyword(s):  
Structural Optimization ◽  
Response Surface ◽  
Optimization Problems ◽  
Structural Characteristics ◽  
Three Dimensional ◽  
Structural Response ◽  
Continuous Functions ◽  
Small Scale ◽  
Multiscale Approach ◽  
Free Material

AbstractThis paper develops a robust framework for the multiscale design of three-dimensional lattices with macroscopically tailored thermal and thermo-structural characteristics. A multiscale approach is implemented where the discrete evaluations of small-scale lattice unit cell characteristics are converted to response surface models so that the properties exist as continuous functions of the lattice micro-parameters. The derived framework constitutes free material optimization in the space of manufacturable lattice micro-architecture. The optimization of individual lattice member dimensions is enabled by the adjoint method and the explicit expressions of the response surface material property sensitivities. The approach is demonstrated by solving thermal and thermo-structural optimization problems, significantly extending previous work which focused on linear structural response. The thermal optimization solution shows a design with improved optimality compared to the SIMP methodology. The thermo-structural optimization solution demonstrates the method’s capability for attaining a prescribed displacement in response to temperature gradients.

Extrusion-Based 3D Printing for Pharmaceuticals: Contemporary Research and Applications

2019 ◽  
Vol 24 (42) ◽  
pp. 4991-5008 ◽  
Author(s):  
Mohammed S. Algahtani ◽  
Abdul Aleem Mohammed ◽  
Javed Ahmad
Keyword(s):  
Cosmetic Surgery ◽  
Fused Deposition Modeling ◽  
Personalised Medicine ◽  
Organ Transplant ◽  
Three Dimensional ◽  
Dosage Forms ◽  
Release Profile ◽  
Small Scale ◽  
Drug Release Profile ◽  
Fused Deposition

Three-dimensional printing (3DP) has a significant impact on organ transplant, cosmetic surgery, surgical planning, prosthetics and other medical fields. Recently, 3 DP attracted the attention as a promising method for the production of small-scale drug production. The knowledge expansion about the population differences in metabolism and genetics grows the need for personalised medicine substantially. In personalised medicine, the patient receives a tailored dose and the release profile is based on his pharmacokinetics data. 3 DP is expected to be one of the leading solutions for the personalisation of the drug dispensing. This technology can fabricate a drug-device with complicated geometries and fillings to obtain the needed drug release profile. The extrusionbased 3 DP is the most explored method for investigating the feasibility of the technology to produce a novel dosage form with properties that are difficult to achieve using the conventional industrial methods. Extrusionbased 3 DP is divided into two techniques, the semi-solid extrusion (SSE) and the fused deposition modeling (FDM). This review aims to explain the extrusion principles behind the two techniques and discuss their capabilities to fabricate novel dosage forms. The advantages and limitations observed through the application of SSE and FDM for fabrication of drug dosage forms were discussed in this review. Further exploration and development are required to implement this technology in the healthcare frontline for more effective and personalised treatment.

scholarly journals Coupled Fluid–Solid Numerical Simulation for Flow Field Characteristics and Supporting Performance of Flexible Support Cylindrical Gas Film Seal

Aerospace ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 97
Author(s):  
Junfeng Sun ◽  
Meihong Liu ◽  
Zhen Xu ◽  
Taohong Liao ◽  
Xiangping Hu ◽  
...  
Keyword(s):  
Flow Field ◽  
Film Thickness ◽  
Fluid Dynamic ◽  
Structural Characteristics ◽  
Structural Parameters ◽  
Equivalent Stress ◽  
Three Dimensional ◽  
High Rotational Speed ◽  
Flexible Support ◽  
Flow Field Characteristics

A new type of cylindrical gas film seal (CGFS) with a flexible support is proposed according to the working characteristics of the fluid dynamic seal in high-rotational-speed fluid machinery, such as aero-engines and centrifuges. Compared with the CGFS without a flexible support, the CGFS with flexible support presents stronger radial floating characteristics since it absorbs vibration and reduces thermal deformation of the rotor system. Combined with the structural characteristics of a film seal, an analytical model of CGFS with a flexible wave foil is established. Based on the fluid-structure coupling analysis method, the three-dimensional flow field of a straight-groove CGFS model is simulated to study the effects of operating and structural parameters on the steady-state characteristics and the effects of gas film thickness, eccentricity, and the number of wave foils on the equivalent stress of the flexible support. Simulation results show that the film stiffness increases significantly when the depth of groove increases. When the gas film thickness increases, the average equivalent stress of the flexible support first decreases and then stabilizes. Furthermore, the number of wave foils affects the average foils thickness. Therefore, when selecting the number of wave foils, the support stiffness and buffer capacity should be considered simultaneously.

scholarly journals Quantification of Measurement and Model Effects in Monopile Foundation Scour Protection Experiments

2021 ◽  
Vol 9 (6) ◽  
pp. 585
Author(s):  
Minghao Wu ◽  
Leen De Vos ◽  
Carlos Emilio Arboleda Chavez ◽  
Vasiliki Stratigaki ◽  
Maximilian Streicher ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Flow Field ◽  
Three Dimensional ◽  
Small Scale ◽  
Maximum Wave Height ◽  
Chaotic Flow ◽  
The Mean ◽  
Scour Protection ◽  
Damage Number ◽  
Measurement Effects

The present work introduces an analysis of the measurement and model effects that exist in monopile scour protection experiments with repeated small scale tests. The damage erosion is calculated using the three dimensional global damage number S3D and subarea damage number S3D,i. Results show that the standard deviation of the global damage number σ(S3D)=0.257 and is approximately 20% of the mean S3D, and the standard deviation of the subarea damage number σ(S3D,i)=0.42 which can be up to 33% of the mean S3D. The irreproducible maximum wave height, chaotic flow field and non-repeatable armour layer construction are regarded as the main reasons for the occurrence of strong model effects. The measurement effects are limited to σ(S3D)=0.039 and σ(S3D,i)=0.083, which are minor compared to the model effects.

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