Electronic search programs are effective in identifying patients with minimal trauma fractures

AbstractObjectivesTo understand and identify factors that promote and prevent research participation among early career psychiatrists (ECPs), in order to understand what would encourage more ECPs to pursue a research career.MethodsWe conducted an electronic search of databases (PubMed and the Cochrane library) using the keywords ‘doctors’, ‘trainees’, ‘residents’, ‘physicians’ and ‘psychiatric trainees’ as well as ‘research’ (MeSH) and ‘publishing’ (MeSH). This search was complemented by a secondary hand search.ResultsWe identified 524 articles, of which 16 fulfilled inclusion criteria for this review. The main barriers included lack of dedicated time for research, lack of mentoring and lack of funding. The main facilitators were opportunities to receive mentorship and access to research funding.ConclusionsAction is needed to counteract the lack of ECPs interested in a career in research. Specific programs encouraging ECPs to pursue research careers and having access to mentors could help increase the current numbers of researching clinicians in the field.

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Dampak Anemi Defisiensi Besi pada Kehamilan : a Literature Review

Gaster | Jurnal Ilmu Kesehatan ◽

10.30787/gaster.v18i1.464 ◽

2020 ◽

Vol 18 (1) ◽

pp. 50

Author(s):

Lilik Hidayanti ◽

M.Zen Rahfiludin

Keyword(s):

Literature Review ◽

Search Engine ◽

Electronic Search

Ibu hamil yang menderita anemia defisiensi besi dapat memberikan dampak negative pada kesehatan ibu maupun bayi yang dilahirkan sehingga dapat meningkatkan angka kematian ibu (AKI) dan angka kematian anak (AKB). Literature review ini bertujuan untuk melakukan telaah terhadap artikel-artikel hasil penelitian eksplanatori dan eksperimental yang dipublikasikan 10 tahun yang lalu atau mulai dari tahun 2008 terkait dengan dampak anemia defisiensi besi pada ibu saat hamil dengan outcome kehamilannya seperti prematuritas, BBLR, kejadian preeklamsi, perkembangan kognitif anak dan kematian bayi. Hasil penelusuran melalui 4 electronic search engine yaitu Proquest, CINAHL Medline, dan Scopus menemukan 220 artikel. Setelah dilakukan proses skrining berdasarkan kriteria inklusi yang ditetapkan, maka diperoleh 50 artikel yang akan ditelaah. Hasil telaah artikel yang telah kami lakukan menemukan bahwa paling banyak (21) artikel membahas mengenai dampak anemia defisiensi besi pada ibu hamil dengan kejadian BBLR, 18 artikel dengan kejadian prematuritas, 6 artikel dengan perkembangan mental anak, dan sisanya (5) artikel dengan kadar zat besi dalam tubuh bayi baru lahir dan ourcome kehamilan yang lainnya. Hasil penelitian di berbagai Negara baik Negara berkembang maupun Negara maju menunjukan bahwa anemia yang terjadi pada masa kehamilan dapat memberikan dampak kelahiran dengan BBLR, prematuritas, kematian neonatus, anemia neonatus, kelahiran denga metode sectio, hambatan perkembangan mental, dan rendahnya skor APGAR.

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Impact of Vibration on the Levels of Biomarkers: A Systematic Review

The Journal of Indian Orthodontic Society ◽

10.1177/03015742211019520 ◽

2021 ◽

pp. 030157422110195

Author(s):

Ashish Agrawal ◽

TM Chou

Keyword(s):

Systematic Review ◽

Web Of Science ◽

Tooth Movement ◽

Orthodontic Tooth Movement ◽

Cochrane Collaboration ◽

Risk Of Bias ◽

Cochrane Library ◽

Inclusion Criteria ◽

Electronic Search ◽

Proquest Dissertation

Introduction: The objective of this systematic review is to assess the effect of vibrational force on biomarkers for orthodontic tooth movement. Methods: An electronic search was conducted for relevant studies (up to December 31, 2020) on the following databases: Pubmed, Google scholar, Web of Science, Cochrane Library, Wiley Library, and ProQuest Dissertation Abstracts and Thesis database. Hand searching of selected orthodontic journals was also undertaken. The selected studies were assessed for the risk of bias in Cochrane collaboration risk of bias tool. The “traffic plot” and “weighted plot” risk of bias distribution are designed in the RoB 2 tool. The 2 authors extracted the data and analyzed it. Results: Six studies fulfilled the inclusion criteria. The risks of biases were high for 4, low and some concern for other 2 studies. The biomarkers, medium, device, frequency and duration of device, as well as other data were extracted. The outcomes of the studies were found to be heterogenous. Conclusion: One study showed highly statistically significant levels of IL-1 beta with <.001. Rate of tooth movement was correlated with levels of released biomarkers under the influence of vibrational force in 3 studies, but it was found to be significant only in 1 study. It was further observed that vibration does not have any significant reduction in pain and discomfort.

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A novel technique for mapping biopsy of bile duct cancer

Endoscopy ◽

10.1055/a-1248-2138 ◽

2020 ◽

Author(s):

Hirokazu Okada ◽

Norimitsu Uza ◽

Tomoaki Matsumori ◽

Shimpei Matsumoto ◽

Yuya Muramoto ◽

...

Keyword(s):

Bile Duct ◽

Intrahepatic Bile Duct ◽

Preoperative Assessment ◽

Median Number ◽

Novel Technique ◽

Minimal Trauma ◽

Adequate Sampling ◽

Novel Method ◽

Longitudinal Extension ◽

Mapping Biopsy

Abstract Background Accurate preoperative assessment of the longitudinal extension of perihilar cholangiocarcinoma (PHCC) is essential for treatment planning. Mapping biopsies for PHCC remain challenging owing to technical difficulties and insufficient sample amounts. The aim of this study was to investigate the usefulness of a novel technique for mapping biopsies of PHCC. Methods Our novel method focused on a biliary stent delivery system for mapping biopsies. Fifty patients with PHCC undergoing endoscopic transpapillary mapping biopsy using the novel method were reviewed from August 2015 to June 2019. Results The median number of biopsy samples was six (range 1 – 17), and the rate of adequate sampling was 91.4 % (266 /291). Biopsy from the intrahepatic bile duct was possible in 82.0 % of patients (41 /50), and negative margins were confirmed in the resected specimens from 34 /39 patients who underwent surgery (87.2 %). None of the patients had post-endoscopic retrograde cholangiopancreatography pancreatitis. Conclusions With our novel method, accurate assessment of the longitudinal extension of PHCC might be expected with minimal trauma to the duodenal papilla.

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Otitis Media and Obesity—An Unusual Relationship in Children

Healthcare ◽

10.3390/healthcare9040458 ◽

2021 ◽

Vol 9 (4) ◽

pp. 458

Author(s):

Cristina Gavrilovici ◽

Elena-Lia Spoială ◽

Anca-Viorica Ivanov ◽

Adriana Mocanu ◽

Violeta Ștreangă ◽

...

Keyword(s):

Risk Factors ◽

Otitis Media ◽

Tobacco Exposure ◽

Taste Changes ◽

Electronic Search ◽

Obesity And Overweight ◽

High Incidence ◽

Ear Infections ◽

The Relationship ◽

Published Research

Otitis media (OM) represents a public health matter, being the main cause of preventable hearing loss in pediatric patients. Besides well-established risk factors for developing OM, such as craniofacial abnormalities, prematurity, low birth weight, or tobacco exposure, there is evidence that obesity could be associated with a high incidence of OM. Our aim is to perform a literature review on the state of current published research on the relationship between OM and obesity and to discuss the interconnectivity between these two entities. We conducted an electronic search in PubMed and EMBASE databases. Out of 176 references, 15 articles were included in our study. Our findings suggest that obesity and overweight might be risk factors for developing OM, and vice versa. The main mechanisms for developing OM in obese patients include alteration in cytokine profile, increased gastroesophageal reflux, and/or fat accumulation. Conversely, ear infections exposure might increase the risk of obesity, mostly by taste changes through middle ear cavity inflammation.

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A Bibliometric Evaluation of the Top 100 Cited Dimethyl Fumarate Articles

Molecules ◽

10.3390/molecules26041085 ◽

2021 ◽

Vol 26 (4) ◽

pp. 1085

Author(s):

Francisco Javier García-Fernández ◽

Alba Estela García-Fernández ◽

Ichiro Ikuta ◽

Eduardo Nava ◽

Julian Solis García del Pozo ◽

...

Keyword(s):

Dimethyl Fumarate ◽

Original Research ◽

H Index ◽

Early Access ◽

Research Areas ◽

Electronic Search ◽

Time Period ◽

The Usa ◽

Immunomodulatory Drug ◽

Number Of Citations

Dimethyl fumarate is a cytoprotective and immunomodulatory drug used in the treatment of multiple sclerosis. We performed a bibliometric study examining the characteristics and trends of the top 100 cited articles that include dimethyl fumarate in the title. On 21 September 2020 we carried out an electronic search in the Web of Science (WOS), seeking articles that include the following terms within the title: dimethyl fumarate, BG-12, or Tecfidera. To focus our investigation on original research, we refined the search to include only articles, early access, others, case report, and clinical trials. We obtained a total of 1115 items, which were cited 7169 times, had a citation density of 6.43 citations/item, and an h-index of 40. Around 2010, there was a jump in the number of published articles per year, rising from 5 articles/year up to 12 articles/year. We sorted all the items by the number of citations and selected the top 100 most cited (T100). The T100 had 4164 citations, with a density of 37 citations/year and contained 16 classic research articles. They were published between 1961 and 2018; the years 2010–2018 amassed nearly 80% of the T100. We noted 17 research areas with articles in the T100. Of these, the number one ranking went to neurosciences/neurology with 39 articles, and chemistry ranked second on the T100 list with 14 items. We noticed that the percentage of articles belonging to different journals changed depending on the time period. Chemistry held the highest number of papers during 1961–2000, while pharmacology andneurosciences/neurology led the 2001–2018 interval. A total of 478 authors from 145 institutions and 25 countries were included in the T100 ranking. The paper by Gold R et al. was the most successful with 14 articles, 1.823 citations and a density of 140.23 citations/year. The biotechnological company Biogen led the T100 list with 20 articles. With 59 published articles, the USA was the leading country in publications. We concluded that this study analyzed the use of and research on dimethyl fumarate from a different perspective, which will allow the readership (expert or not) to understand the relevance of classic and recent literature on this topic.

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Are sniffer dogs a reliable approach for diagnosing SARS-CoV-2 infection?

Diagnosis ◽

10.1515/dx-2021-0034 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Giuseppe Lippi ◽

Camilla Mattiuzzi ◽

Brandon M. Henry

Keyword(s):

Severe Acute Respiratory Syndrome ◽

Operating Characteristic ◽

Characteristic Curve ◽

Pooled Analysis ◽

Diagnostic Efficiency ◽

Diagnostic Specificity ◽

Summary Receiver Operating Characteristic ◽

Electronic Search ◽

Individual Variations ◽

Infected Material

Abstract Objectives Despite inter-individual variations in their diagnostic efficiency, dogs have been trained to investigate many human pathologies, especially cancer, diabetes, migraine, seizures and even infectious diseases. To this end, we performed a critical review and pooled analysis of current scientific literature on the performance of dogs trained for identifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive human specimens. Methods We carried out an electronic search in PubMed, Scopus and Web of Science with the keywords “dog(s)” AND “sniffer” OR “scent” OR “smell” AND “SARS-CoV-2” OR “severe acute respiratory syndrome coronavirus 2” OR “coronavirus disease 2019” OR “COVID-19” within all fields, without date or language restrictions, to identify studies describing dogs’ performance for identifying SARS-CoV-2 infected material. Results Three studies could be finally included in pooled analysis, totaling 17 dogs (47% females), aged between 0.5 and 12 years. The pooled diagnostic sensitivity was 0.88 (95% CI, 0.84–0.91; I 2, 85.3%), the diagnostic specificity 0.99 (95% CI, 0.99–0.99; I 2, 97.4%), whilst the area under the summary receiver operating characteristic curve (SROC) was 0.979 (standard error, 0.003). Conclusions The notable performance observed in this pooled analysis would persuade us to suggest that adequately trained dogs could represent an intriguing and sustainable resource for purposes of rapid SARS-CoV-2 mass screening.

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The assessment and pharmacological management of osteoporosis after admission for minimal‐trauma fracture at a major metropolitan centre

Journal of Pharmacy Practice and Research ◽

10.1002/jppr.1674 ◽

2020 ◽

Vol 50 (6) ◽

pp. 481-489

Author(s):

Ria E. Hopkins ◽

Victoria Warner ◽

Shoshana Sztal‐Mazer ◽

Susan Poole ◽

Amy Page

Keyword(s):

Pharmacological Management ◽

Minimal Trauma Fracture ◽

Minimal Trauma

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Minimal trauma causing fractures in patients with spinal cord injury

Disability and Rehabilitation ◽

10.3109/09638289209167081 ◽

1992 ◽

Vol 14 (2) ◽

pp. 108-109 ◽

Cited By ~ 36

Author(s):

J. F. Keating ◽

M. Kerr ◽

M. Delargy

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Minimal Trauma ◽

Cord Injury

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Alcohol use and bipolar disorder comorbidity: Synthesis and perspectives

European Psychiatry ◽

10.1016/j.eurpsy.2017.01.535 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S470-S470

Author(s):

A. Dahdouh ◽

B. Semaoune ◽

A. Tremey ◽

L. Samalin ◽

V. Flaudias ◽

...

Keyword(s):

Bipolar Disorder ◽

Alcohol Use ◽

Dual Diagnosis ◽

Public Health Problem ◽

Major Public Health Problem ◽

Systematic Screening ◽

Electronic Search ◽

Clinical Interest ◽

Competing Interest ◽

The Relationship

ObjectiveAlcohol use disorders and bipolar disorder commonly co-occur and both are associated with more pejorative outcomes, thus constituting a major public health problem. We undertook this synthetic review to provide an update on this issue in order to clarify the nature of the relationship between the two disorders, improve clinical outcomes, prevent complications and therefore optimize management of patients.MethodsWe conducted an electronic search by keywords in databases MEDLINE, EMBASE, PsychINFO, published in English and French from January1985 to December 2015.ResultsThe AUD prevalence is important among BD patients in whom the effects of alcohol are more severe. However, in terms of screening, it appears that the comorbidity is not systematically sought. The concept of co-occurrence finds its clinical interest in the development of specific screening and therapeutic strategies. To date, there are only few recommendations about the management of dual diagnosis and the majority of them support “integrated” approaches.ConclusionsRecommendations should emphasize this strong co-occurrence and promote systematic screening and offered integrated cares.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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