scholarly journals A Bibliometric Evaluation of the Top 100 Cited Dimethyl Fumarate Articles

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1085
Author(s):  
Francisco Javier García-Fernández ◽  
Alba Estela García-Fernández ◽  
Ichiro Ikuta ◽  
Eduardo Nava ◽  
Julian Solis García del Pozo ◽  
...  

Dimethyl fumarate is a cytoprotective and immunomodulatory drug used in the treatment of multiple sclerosis. We performed a bibliometric study examining the characteristics and trends of the top 100 cited articles that include dimethyl fumarate in the title. On 21 September 2020 we carried out an electronic search in the Web of Science (WOS), seeking articles that include the following terms within the title: dimethyl fumarate, BG-12, or Tecfidera. To focus our investigation on original research, we refined the search to include only articles, early access, others, case report, and clinical trials. We obtained a total of 1115 items, which were cited 7169 times, had a citation density of 6.43 citations/item, and an h-index of 40. Around 2010, there was a jump in the number of published articles per year, rising from 5 articles/year up to 12 articles/year. We sorted all the items by the number of citations and selected the top 100 most cited (T100). The T100 had 4164 citations, with a density of 37 citations/year and contained 16 classic research articles. They were published between 1961 and 2018; the years 2010–2018 amassed nearly 80% of the T100. We noted 17 research areas with articles in the T100. Of these, the number one ranking went to neurosciences/neurology with 39 articles, and chemistry ranked second on the T100 list with 14 items. We noticed that the percentage of articles belonging to different journals changed depending on the time period. Chemistry held the highest number of papers during 1961–2000, while pharmacology andneurosciences/neurology led the 2001–2018 interval. A total of 478 authors from 145 institutions and 25 countries were included in the T100 ranking. The paper by Gold R et al. was the most successful with 14 articles, 1.823 citations and a density of 140.23 citations/year. The biotechnological company Biogen led the T100 list with 20 articles. With 59 published articles, the USA was the leading country in publications. We concluded that this study analyzed the use of and research on dimethyl fumarate from a different perspective, which will allow the readership (expert or not) to understand the relevance of classic and recent literature on this topic.

2020 ◽  
Vol 21 (9) ◽  
pp. 685-703
Author(s):  
Waseem Hassan ◽  
Jean Paul Kamdem ◽  
Mohammad Amjad Kamal ◽  
Joao Batista Teixeira da Rocha

Background: Scopus is regularly covering Current Drug Metabolism from 2000 onwards. Objective: The major objective is to perform the 1st bibliometric analysis of Current Drug Metabolism (CDM). Methods: The data was retrieved from Scopus in April-May 2020 for detail analysis. Results: The total number of publications was found to be 1551, with 955 reviews (61.57%) and 466 articles (30.05%). From 2000 onwards, we calculated the relative growth rate and doubling time. Based on the number of publications, total 4418 authors, 3235 institutions and 83 countries were directly involved in all publications. M.A. Kamal is the highly productive scientist with fifty-three (53 or 3.73%) publications, King Abdulaziz University is the top university with the highest number of publications (58 or 4.13%) and the USA is the top-ranked country with 365 publications (25.96%). We also provided the h-index, total citations (TC), h-index without self-citations (WSC) and total WSC of the top ten authors, universities and countries. In citations analysis, Prof. Zhou S.F. was the top scientist with the highest (1594) number of citations. In institutional category Department of Drug Metabolism, Merck Research Laboratories, Rahway, United States, is the top ranked institutes with 654 total citations. While, United States is the top-ranked country with 18409 total citations. In co-words analysis, 3387, 30564 and 17333 terms in titles of the manuscripts, abstracts and keywords were recorded, respectively. This indicated that CDM principally focused on understanding drug development ranging from its efficacy to delivery, metabolism, distribution, safety and mechanism of actions. Similarly, various specific drugs were thoroughly discussed in publications. Various enzymatic, genetics, proteins and cancer-related aspects were also described. For data presentations, we used VOSviewer graphical maps. Conclusion: The data confirm that CDM showed continuous growth in the number of publications and citations. However significant measures are needed to make overall progress and improve the rankings in relevant categories.


2021 ◽  

Purpose: To assess the present landscape and future research directions, a bibliometric analysis was performed to identify the characteristics of the 100 most-cited articles (T100 articles) on CRPC research. Methods: A list of the T100 articles investigating CRPC was generated by searching the Web of Science (WoS) Core Collection database. Different characteristics of the T100 articles, including the countries/territories, journals, authors, and research areas, were analyzed. Results: The number of citations of T100 articles published between 1992 and 2017 ranged from 282 to 3594, with an average of 654.9 citations. According to the topic of the article, ''Mechanisms related to tumor progression or metastasis'' ranked first with 41 T100 articles, while immunotherapy ranked fourth with 7 T100 articles. The T100 articles originated from 31 countries, with more than half originating from the USA (n = 89). Professor Scher HI published the most T100 articles as the first author (4) and as the corresponding author (5), while Pro De Bono JS from the Institute of Cancer Research published 3 articles as the first author and 8 articles as the corresponding author. The journal Cancer Research published 20 T100 articles with a total of 8946 citations. The number of T100 articles(r = 0.485, P = 0.01) and the total number of citations(r = 0.626, P < 0.001) were all positively correlated with the IF of the journal. Conclusions: This analysis offers a historical perspective on the progress and attempts to reveal future trends in CRPC research using bibliometric analysis. This study's results suggest that immunotherapy and the study of androgen receptors as well as their signaling axes will possibly be hot topics and trends in CRPC research.


2018 ◽  
Vol 103 (1) ◽  
pp. 18-25 ◽  
Author(s):  
Matthew Yu Heng Wong ◽  
Nicholas Y Q Tan ◽  
Charumathi Sabanayagam

We analysed the 100 top cited articles in ophthalmology to identify and characterise the most influential articles of the past four decades. Two independent investigators searched the Scopus database to determine the 100 most frequently cited articles in ophthalmology (T100-Eye) and general non-ophthalmology journals (T100-Gen) published from 1975 to December 2017. The T100-Eye list consisted of 83 original articles and 17 reviews, and the number of citations ranged from 582 to 2833. Seventy-eight of these articles were published in three journals alone (impact factor (IF): 5.05–8.2), led by the Archives of Ophthalmology. The T100-Gen list consisted of 84 original articles and 16 reviews and the number of citations ranged from 358 to 3272. Forty-five of these articles were published in four journals alone (IF: 9.66–72.41). In both lists, majority of the first authors were from the USA (T100-Eye, n=80; T100-Gen, n=66), and were men (n=76 in T100-Eye; n=72 in T100-Gen). With regard to the article type, in the T100-Eye, among the 83 original research articles, most were randomised controlled trials (n=26) or clinical observational studies related to description of a new condition or new management (n=26). In the T100-Gen, of the 84 original research articles, many were clinical observational studies (n=27) or basic science research (n=26). In both lists, the most frequently examined diseases were age-related macular degeneration, diabetic retinopathy and glaucoma. Our analysis reveals landmark articles, trends and medical advancements in ophthalmology over the past four decades. It also highlights gender disparity and influence of the USA in seminal ophthalmic research.


2015 ◽  
Vol 46 (1) ◽  
pp. 96-106 ◽  
Author(s):  
Emma Barker ◽  
Kairi Kõlves ◽  
Diego De Leo

Asthma is a highly prevalent chronic condition worldwide, and is particularly common in younger people compared to other chronic conditions. Asthma can result in a number of symptoms that are detrimental to the quality of life of sufferers. The aim of the present systematic literature review was to analyse the existing literature on the relationship between asthma and fatal and nonfatal suicidal behaviours.Articles were retrieved from Scopus, PubMed, ProQuest and Web of Knowledge. We searched for the terms (suicid* OR self-harm) AND (asthma* OR “bronchial hyperreactivity”) published in English-language peer-reviewed journals between 1990 and December 2014. Original research papers providing empirical evidence about the potential link between asthma and suicidal behaviours were included.The initial search identified 746 articles. Specific limiting criteria reduced the number of articles to the 19 articles that were finally included in the systematic review.The review found a potential link between asthma and suicide mortality, ideation and attempts across the age groups. Limitations of the review include the restriction to English-language papers published within the chosen time period, the limited number of papers involving suicide mortality, and the fact that the majority of papers originated from the USA.


2014 ◽  
Vol 1073-1076 ◽  
pp. 2728-2733
Author(s):  
Jing Wen Zhan ◽  
Lan Zhou Chen ◽  
Song Hong

The study used the bibiometric analysis to assess papers on emission inventory from 2001-2012, based on the SCIE and SSCI databases. The paper analyzed publication outputs, subject categories, major journals, authors’ outputs, geographic distribution of publications, international collaboration and author keywords. Our research identified a total of 5995 emission inventory-related publications during the period. Most of the papers related to emission inventory were published in journals linkd to the atmosphere. Streets, DG from Argonne National Laboratory contributed most in the research of emission inventory whose total papers, total citations, the average number of citations and H-index were all in the leading position. The USA, with the most independent and internationally collaborative papers, cooperated with China most. Global emission inventory research focused on life cycle assessment, greenhouse gases, models, remote sensing and so on, which may serve as a foundation for further research in emission inventory field.


2018 ◽  
Vol 6 (2) ◽  
pp. 18 ◽  
Author(s):  
Serdar Çiftci

This study examines the tendencies of studies carried out using text mining methods under the title of “serious game”. A query was run for the “serious game” keyword in the Web of Science search engine to acquire the data. The study included publications that were scanned in the SCI-EXPANDED, SSCI and A&HCI indices between 2007-2017. Information could be acquired for a total of 1431 publications. Firstly, the obtained data were cleansed of erroneous and unnecessary information by way of a pre-process. According to the data set cleansed of errors, the total number of common citations was 12701, number of citations per publication was 8.88, whereas h-index was determined as 51. Analyses were carried out by examining all “serious games” publications on the basis of: year, author, journal/symposium name, keywords, research areas and common citation parameters. According to the results, there was a continuous increase over time in the number of publications and citations. Even though “serious games” is a topic that is frequently studied in the field of education technology studies in fields such as psychology, health care sciences, environmental sciences, ecology, public environmental occupational health, rehabilitation, business economics and psychiatry shows that “serious game” is also a popular topic for studies in different disciplines.


2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Yong Chen ◽  
Feiyang Yu ◽  
Ziwen Cheng ◽  
Qiuxia Jin ◽  
Zhi Pei ◽  
...  

The cellular automata algorithm is one of the most important developments recently and is becoming an area of great potential in scheduling problems. There has been an increase in the quality and quantity of publications related to this topic. To formally illustrate the research status of the cellular automata algorithm at the global level, bibliometric analysis was used based on the Web of Science and Scopus databases, and 3086 documents were retrieved from different countries and regions. Institutions, journals, authors, research areas, author keywords, and highly cited articles are discussed in detail. The results show that the USA and China are the dominant countries in this field. The USA is the most active country cooperating with other 47 countries or regions, especially with China. The Journal of Cellular Automata is the most productive journal in this field, and the Democritus University of Thrace is the most productive institution also with the highest h-index. “Computer Science” is the most investigated area, with 544 documents involved. In addition, the major topics focused by author keywords are “genetic algorithm,” “swarm intelligence,” and “evolutionary computation.” In addition, the cellular automata algorithm is viewed as a new and effective method to solve the scheduling problems in manufacturing system; meanwhile, historical developments of the application of cellular automata in scheduling are displayed and analyzed.


2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Waleed M. Sweileh

Abstract Background Antimicrobial resistance (AMR) is a global challenge that requires a “One Health” approach to achieve better public health outcomes for people, animals, and the environment. Numerous bibliometric studies were published on AMR in humans. However, none was published in food-producing animals. The current study aimed at assessing and analyzing scientific publications on AMR in food-producing animals. Method A validated search query was developed and entered in Scopus advanced search function to retrieve and quantitatively analyze relevant documents. Bibliometric indicators and mapping were presented. The study period was from 2000 to 2019. Results The search query retrieved 2852 documents. During the period from 2015 to 2019, approximately 48% of the retrieved documents were published. The article about the discovery of plasmid-mediated colistin resistance in pigs received the highest number of citations (n = 1970). The Journal of Food Protection (n = 123; 4.3%) ranked first in the number of publications while the Applied and Environmental Microbiology journal ranked first in the number of citations per document. The USA led with 576 (20.2%) documents followed by China (n = 375; 13.1%). When the number of publications was standardized by income and population size, India (n = 51.5) ranked first followed by China (n = 38.3) and Brazil (n = 13.4). The growth of publications from China exceeded that of the USA in the last 3 years of the study period. Research collaboration in this field was inadequate. Mapping author keywords showed that E. coli, Salmonella, poultry, Campylobacter, chicken, cattle, and resistant genes were most frequent. The retrieved documents existed in five research themes. The largest research theme was about AMR in Salmonella in food-producing animals. The most recent research theme was about the dissemination and molecular transfer of AMR genes into the environment and among different bacterial strains. Conclusion Hot spots of research on AMR in food-producing animals match the world regions of reported hot spots of AMR in animals. Research collaboration in this field is of great importance, especially with low- and middle-income countries. Data on AMR need to be collected nationally and internationally to implement the “One Health” approach in the fight against AMR.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Guanrong Peng ◽  
Zhenhua Guan ◽  
Yunfei Hou ◽  
Jiaxiang Gao ◽  
Wenqun Rao ◽  
...  

Abstract Background Hip fracture is common and carries high morbidity and mortality; thus, it has become a vital concern. We aim to analyse the present status, worldwide trends in hip fracture and state of clinical research. Methods Publications from 2000 to 2019 were retrieved from the Web of Science database and analysed using a bibliometric methodology. VOSviewer software was utilised for analysis. Results In total, 6139 publications were included, and publications increased annually from 152 in 2000 to 592 in 2019. U.S. researchers have produced the most publications, the highest H-index and the greatest number of citations. Osteoporosis International has published the most papers on the topic. Leading researchers, contributing institutions, their cooperative relationships and scientific masterpieces have been identified. The publications can be divided into five clusters: ‘mortality’, ‘surgical management’, ‘rehabilitation’, ‘osteoporosis’ and ‘epidemiology’. A clear developing trend was described, which began with fracture epidemiology and prevention, transitioned to perioperative management, orthogeriatric care and patient safety and then to functional recovery, disease burden and national audits in recent times. Conclusions Hip fractures result in conditions that extend far beyond orthopaedics concerning epidemiology and preventive medicine, internal medicine and endocrinology, as well as critical care and gerontology. Interest, research and publications are on the rise.


2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Ron E. Gray ◽  
Alexis T. Riche ◽  
Isabel J. Shinnick-Gordon ◽  
James C. Sample

AbstractDespite earning half of all science and engineering undergraduate degrees between 2007 and 2016 in the USA, women were awarded only 39% of earth science degrees in the same time period. In order to better understand why women are both choosing and staying in geology programs, we conducted a multi-case study of nine current female undergraduate geology majors at a large public university in the USA within a department that is at gender parity among its undergraduate majors. The main data source was audio-recorded critical incident interviews of each participant. Data from the interviews were analyzed through an iterative coding process using codes adapted from previous studies that focused on factors both internal and external to the department. The students said that personal interests, influence by others outside of the department, and introductory classes attracted them to the geology program, but once declared, departmental factors such as relationship with faculty caused them to stay. We also found an emphasis on female role models, especially those teaching introductory courses. We believe this study offers important insights into the ways in which factors leading to recruitment and retention play out in the lived experiences of female geology majors.


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