scholarly journals Polyene macrolide biosynthesis in streptomycetes and related bacteria: recent advances from genome sequencing and experimental studies

2016 ◽  
Vol 100 (9) ◽  
pp. 3893-3908 ◽  
Author(s):  
Patrick Caffrey ◽  
Eimear De Poire ◽  
James Sheehan ◽  
Paul Sweeney
Sensors ◽  
2021 ◽  
Vol 21 (13) ◽  
pp. 4425
Author(s):  
Ana María Pineda-Reyes ◽  
María R. Herrera-Rivera ◽  
Hugo Rojas-Chávez ◽  
Heriberto Cruz-Martínez ◽  
Dora I. Medina

Monitoring and detecting carbon monoxide (CO) are critical because this gas is toxic and harmful to the ecosystem. In this respect, designing high-performance gas sensors for CO detection is necessary. Zinc oxide-based materials are promising for use as CO sensors, owing to their good sensing response, electrical performance, cost-effectiveness, long-term stability, low power consumption, ease of manufacturing, chemical stability, and non-toxicity. Nevertheless, further progress in gas sensing requires improving the selectivity and sensitivity, and lowering the operating temperature. Recently, different strategies have been implemented to improve the sensitivity and selectivity of ZnO to CO, highlighting the doping of ZnO. Many studies concluded that doped ZnO demonstrates better sensing properties than those of undoped ZnO in detecting CO. Therefore, in this review, we analyze and discuss, in detail, the recent advances in doped ZnO for CO sensing applications. First, experimental studies on ZnO doped with transition metals, boron group elements, and alkaline earth metals as CO sensors are comprehensively reviewed. We then focused on analyzing theoretical and combined experimental–theoretical studies. Finally, we present the conclusions and some perspectives for future investigations in the context of advancements in CO sensing using doped ZnO, which include room-temperature gas sensing.


2014 ◽  
Vol 22 (2) ◽  
pp. 99-108
Author(s):  
Krzysztof Sadowski ◽  
Sergiusz Jóźwiak

SUMMARYIntroduction.Epilepsy that is associated with neurocutaneous disorders seriously deteriorates quality of life and cognitive outcome of affected children. Recent advances in epilepsy pathophysiology raise hopes for better treatment results in this difficult group of patients.Aim.The aim of this review is to present recent treatment recommendations as well as current research progress in the most frequent neurocutaneous disorders.Material and methods.We analyzed PubMed database to select the most prominent and recent (up to 2014 year) publications on the treatment and mechanisms of epilepsy in selected neurocutaneous disorders. We aimed to emphasize evidence-based medicine recommendations as well as basic experimental studies dealing with molecular mechanisms of epileptogenesis.Discussion and conclusions.Recent advances in disease-modifying treatment options such as mTOR inhibitors in patients with tuberous sclerosis complex open up new perspectives for neurologists. Traditional resective surgery has still a major role as a treatment of choice in carefully selected cases.


2017 ◽  
Vol 11 ◽  
pp. 117954681773952 ◽  
Author(s):  
Makarand Deo ◽  
Seth H Weinberg ◽  
Patrick M Boyle

This Special Collection will gather all studies highlighting recent advances in theoretical and experimental studies of arrhythmia, with a specific focus on research seeking to elucidate links between calcium homeostasis in cardiac cells and organ-scale disruption of heart rhythm.


2007 ◽  
Vol 25 (3) ◽  
pp. 347-363 ◽  
Author(s):  
P.V. Nickles ◽  
S. Ter-Avetisyan ◽  
M. Schnürer ◽  
T. Sokollik ◽  
W. Sandner ◽  
...  

New perspectives have been opened up in the field of laser–matter interactions due to recent advances in laser technology, leading to laser systems of high contrast and extreme intensity values, where the frontier of maximum intensity is pushed now to about 1022 W/cm2. Many striking phenomena such as laser-acceleration of electrons up to the GeV level, fast moving ions with kinetic energies of several 10s of MeV, as well as nuclear physics experiments have already actuated a broad variety of theoretical as well as experimental studies. Also highly relativistic effects like laser induced electron-positron pair production are under discussion. All these activities have considerably stimulated the progress in understanding the underlying physical processes and possible applications. This article reviews recent advances in the experimental techniques as well as the associated plasma dynamics studies at relativistic intensities performed at the Max-Born-Institute (MBI). Interactions of a laser pulse at intensities above 1019 W/cm2 with water- and heavy-water droplets, as well as, with thin foils are discussed. Rear and front side acceleration mechanisms, particle dynamics inside the dense target, proton source characteristics, strong modulations in proton and deuteron emission spectra, and finally generation of quasi-monoenergetic deuteron bursts are the topics covered in the article.


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