scholarly journals Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy

2020 ◽  
Vol 69 (3) ◽  
pp. 449-463 ◽  
Author(s):  
Remy Thomas ◽  
Hibah Shaath ◽  
Adviti Naik ◽  
Salman M. Toor ◽  
Eyad Elkord ◽  
...  
Keyword(s):  
Lactate Dehydrogenase ◽  
Cancer Immunotherapy ◽  
Lactate Dehydrogenase C ◽  
Novel Targets

scholarly journals Lactate Dehydrogenase C and Energy Metabolism in Mouse Sperm

2011 ◽  
Vol 85 (3) ◽  
pp. 556-564 ◽  
Author(s):  
F. Odet ◽  
S. A. Gabel ◽  
J. Williams ◽  
R. E. London ◽  
E. Goldberg ◽  
...  
Keyword(s):  
Lactate Dehydrogenase ◽  
Energy Metabolism ◽  
Mouse Sperm ◽  
Lactate Dehydrogenase C

Alternative Splicing of Testis-Specific Lactate Dehydrogenase C Gene in Mammals and Pigeon

2012 ◽  
Vol 23 (2) ◽  
pp. 114-123 ◽  
Author(s):  
Lin Huang ◽  
Yaqiu Lin ◽  
Suyu Jin ◽  
Wei Liu ◽  
Yaou Xu ◽  
...  
Keyword(s):  
Alternative Splicing ◽  
Lactate Dehydrogenase ◽  
Lactate Dehydrogenase C

Assignment of human gene encoding testis-specific lactate dehydrogenase C to chromosome 11, region p14.3-p15.5

1988 ◽  
Vol 14 (5) ◽  
pp. 515-518 ◽  
Author(s):  
Fa-Ten Kao ◽  
Kun C. Wu ◽  
Martha L. Law ◽  
Judith A. Hartz ◽  
Yun-Fai Lau
Keyword(s):  
Lactate Dehydrogenase ◽  
Human Gene ◽  
Chromosome 11 ◽  
Gene Encoding ◽  
Lactate Dehydrogenase C

Results of the safety evaluation of cancer vaccines dealing with novel targets for cancer immunotherapy

2016 ◽  
Vol 259 ◽  
pp. S151-S152
Author(s):  
A. Mancebo ◽  
A.M. Bada ◽  
A. Casacó ◽  
B. González ◽  
A. León ◽  
...  
Keyword(s):  
Cancer Immunotherapy ◽  
Cancer Vaccines ◽  
Safety Evaluation ◽  
Novel Targets

scholarly journals Cloning and Sequence Analysis of Multiple Splice Variants of Lactate Dehydrogenase C in Yak Testes

2008 ◽  
Vol 54 (3) ◽  
pp. 229-232 ◽  
Author(s):  
Qinghua HE ◽  
Jian HONG ◽  
Yucai ZHENG ◽  
Suyu JIN
Keyword(s):  
Lactate Dehydrogenase ◽  
Sequence Analysis ◽  
Splice Variants ◽  
Lactate Dehydrogenase C

scholarly journals DETERMINATION OF DIAGNOSTIC ACCURACY OF BIOCHEMICAL PARAMETERS (CRP, LDH & FERRITIN) IN THE DIAGNOSIS OF COVID-19 IN SUSPECTED COVID CASES

2021 ◽  
Vol 71 (5) ◽  
pp. 1722-26
Author(s):  
Tayyaba Ashiq ◽  
Abdus Sattar ◽  
Nasir Uddin ◽  
Qamar Bashir ◽  
Sajida Shaheen ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Lactate Dehydrogenase ◽  
Diagnostic Accuracy ◽  
Biochemical Parameters ◽  
C Reactive Protein ◽  
Chain Reaction ◽  
Reactive Protein ◽  
Poor Predictor ◽  
Lactate Dehydrogenase C ◽  
Polymerase Chain

Objective: To determine the diagnostic accuracy of the Lactate Dehydrogenase, C-Reactive Protein and Ferritin in suspected patients of COVID-19. Study Design: Cross-sectional validation study. Place and Duration of Study: Pathology department of Combined Military Hospital Lahore in the month of May 2020. Methodology: We included 101 adult (>18 years) symptomatic suspected COVID-19 patients of both genders. Children, pregnant women and asymptomatic patients were excluded from study. Age, gender and results of Reverse Transcriptase Polymerase Chain Reaction, Lactate Dehydrogenase, C-Reactive Protein, ferritin were recorded. Results: Lactate Dehydrodenase had highest sensitivity (75%) with positive predictive value of 71.6% and diagnostic accuracy of 65.3% among three biochemical parameters studied. Receiver Operator Characteristic curve was studied. Area under curve of Lactate Dehydrogenase (AUC=0.65) and Ferritin (AUC=0.59) reflected their ability to prognosticate the presence of COVID19 disease. However, C-Reactive Protein (AUC=0.42) appeared to be a poor predictor of the disease. Conclusion: Raised serum Lactate Dehydrogenase (>490 U/L) and Ferritin (>152 ng/L) levels can be used to predict the Reverse Transcriptase Polymerase Chain Reaction positivity for COVID-19 in the population of suspected patients of COVID19. However, C-Reactive Protein is a poor predictor of COVID-19.

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