Semi-IPN hydrogels based on Poly(vinyl alcohol) for controlled release studies of chemotherapeutic agent and their Swelling characteristics

2008 ◽  
Vol 61 (1) ◽  
pp. 81-90 ◽  
Author(s):  
K. S. V. Krishna Rao ◽  
A. B. V. Kiran Kumar ◽  
K. Madhusudhan Rao ◽  
M. C. S. Subha ◽  
Yong-Ill Lee
Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 691
Author(s):  
O. Sánchez-Aguinagalde ◽  
Ainhoa Lejardi ◽  
Emilio Meaurio ◽  
Rebeca Hernández ◽  
Carmen Mijangos ◽  
...  

Chitosan (CS) and poly (vinyl alcohol) (PVA) hydrogels, a polymeric system that shows a broad potential in biomedical applications, were developed. Despite the advantages they present, their mechanical properties are insufficient to support the loads that appear on the body. Thus, it was proposed to reinforce these gels with inorganic glass particles (BG) in order to improve mechanical properties and bioactivity and to see how this reinforcement affects levofloxacin drug release kinetics. Scanning electron microscopy (SEM), X-ray diffraction (XRD), swelling tests, rheology and drug release studies characterized the resulting hydrogels. The experimental results verified the bioactivity of these gels, showed an improvement of the mechanical properties and proved that the added bioactive glass does affect the release kinetics.


Polymer ◽  
1995 ◽  
Vol 36 (13) ◽  
pp. 2579-2583 ◽  
Author(s):  
Kokoro Lio ◽  
Norihiko Minoura ◽  
Masanobu Nagura

2007 ◽  
Vol 459 (1-2) ◽  
pp. 390-396 ◽  
Author(s):  
El-Refaie Kenawy ◽  
Fouad I. Abdel-Hay ◽  
Mohamed H. El-Newehy ◽  
Gary E. Wnek

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