Comparison of semiquantitative chest CT scoring systems to estimate severity in coronavirus disease 2019 (COVID-19) pneumonia

Abstract Background: lung ultrasound (LUS) and chest computed tomography (chest-CT) are largely employed to evaluate coronavirus-disease-19 (COVID-19) pneumonia. We investigated semi-quantitative LUS and CT scoring in hospitalized COVID-19 patients.Methods: LUS and chest-CT were performed within 24 hours upon admission. Both were analyzed according to semi-quantitative scoring systems. Subgroups were identified according to median LUS score.Results: patients within higher LUS-score group were older (79 vs 60 years, p<0.001), had higher C-reactive protein (CRP) (7.2 vs 1.3 mg/dl, p<0.001) and chest-CT score (10 vs 4, p=0.027) as well as lower PaO2/FiO2 (286 vs 356, p=0.029) as compared to patients within lower scores. We found a significant correlation between scores (r=0.390, p=0.023). Both LUS and CT scores correlated directly with patients age (r=0.586, p<0.001 and r=0.399, p=0.021 respectively) and CRP (r=0.472, p=0.002 and r=0.518, p=0.002 respectively), inversely with PaO2/FiO2 (r=-0.485, p=0.003 and r=-0.440, p=0.017 respectively). LUS-score only showed significant correlation with hs-Troponin T, NT-pro-BNP and creatinine (r=0.433, p=0.019; r=0.411, p=0.027 and r=0.497, p=0.001 respectively).Conclusions: semi-quantitative bedside LUS related to the severity of COVID-19 pneumonia similarly to chest-CT. Correlation of LUS-score with markers of cardiac and renal injury suggests that LUS might contribute to a more comprehensive evaluation of this heterogeneous population.

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Comparison of chest CT severity scoring systems for COVID-19

European Radiology ◽

10.1007/s00330-021-08432-5 ◽

2022 ◽

Author(s):

Ali H. Elmokadem ◽

Ahmad M. Mounir ◽

Zainab A. Ramadan ◽

Mahmoud Elsedeiq ◽

Gehad A. Saleh

Keyword(s):

Scoring Systems ◽

Chest Ct ◽

Severity Scoring

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Diagnostic accuracy of Computed Tomography for Identifying Hospitalization in Patients with Suspected COVID-19

Digital Diagnostics ◽

10.17816/dd46818 ◽

2021 ◽

Author(s):

S. P. Morozov ◽

Roman V. Reshetnikov ◽

Victor A. Gombolevskiy ◽

N. V. Ledikhova ◽

I. A. Blokhin ◽

...

Keyword(s):

Computed Tomography ◽

Diagnostic Accuracy ◽

Scoring System ◽

Scoring Systems ◽

Chest Ct ◽

Ct Scans ◽

Quantitative Ct ◽

System Sensitivity ◽

Thoracic Computed Tomography ◽

Sensitivity Specificity

Background and Objectives The use of computed tomography (CT) in COVID-19 screening is controversial. The controversy is associated with ambiguous characteristics of chest CT as a diagnostic test. The reported values of CT sensitivity and especially specificity calculated using reverse transcription polymerase chain reaction as a reference standard vary widely, raising reasonable doubts about the applicability of the method. The objective of this study was to reevaluate the diagnostic and prognostic value of CT using an alternative approach. Methods This study included 973 symptomatic COVID-19 patients aged 42 17 years, 56% females. For all of them, we reviewed the disease dynamics between the initial and follow-up CT studies using a "CT0-4" visual semi-quantitative grading system to assess the severity of the disease. Sensitivity and specificity were calculated as conditional probabilities that a patient's condition would improve or deteriorate, depending on the results of the initial CT examination. For the calculation of negative (NPV) and positive (PPV) predictive values, we estimated the COVID-19 prevalence in Moscow. The data on total cases of COVID-19 from March 6, 2020, to August 24, 2020, were taken from the Rospotrebnadzor website. We used several ARIMA and EST models with different parameters to fit the data and forecast the incidence. Results The "CT0-4" grading scale demonstrated low sensitivity (28%), but high specificity (95%). The best statistical model for describing the epidemiological situation in Moscow was ARIMA(0,2,1). According to our calculations, with the predicted point prevalence of 3.9%, the values of NPV and PPV would be 97% and 18%, correspondingly. Discussion We associate the low sensitivity and PPV values of the "CT0-4" grading scale with the small sample size of the patients with severe symptoms and non-optimal methodological setup for measuring these specific characteristics. We found that the grading scale was highly specific and predictive for identifying admissions to hospitals of COVID-19 patients. Only 5% of patients assigned to home treatment were eventually hospitalized. Despite the ambiguous accuracy, chest CT proved to be an effective practical tool for patient management during the pandemic, provided that the necessary infrastructure and human resources are available.

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390: The Use of Validated Scoring Systems to Improve Objective Assessment of Comorbid Risk in Men with Localised Prostate Cancer

The Journal of Urology ◽

10.1016/s0022-5347(18)37652-3 ◽

2004 ◽

Vol 171 (4S) ◽

pp. 102-103

Author(s):

Rajinder Singh ◽

Declan Cahill ◽

Rick Popert ◽

Ronald Beaney ◽

Anthony Wierzbicki ◽

...

Keyword(s):

Prostate Cancer ◽

Objective Assessment ◽

Scoring Systems

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Practice materials for learning the scoring systems

Motivation and Personality ◽

10.1017/cbo9780511527937.039 ◽

1992 ◽

pp. 537-630

Author(s):

Carol E. Franz

Keyword(s):

Scoring Systems

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Personal Problem Solving of Partners in Divorce Proceedings

Rorschachiana Journal of the International Society for the Rorschach ◽

10.1027/1192-5604/a000053 ◽

2015 ◽

Vol 36 (1) ◽

pp. 82-103 ◽

Cited By ~ 1

Author(s):

Tereza Soukupova ◽

Petr Goldmann

Keyword(s):

Gender Differences ◽

Problem Solving ◽

Thematic Apperception Test ◽

Scoring Systems ◽

Personal Control ◽

Personality Characteristics ◽

Personal Problem ◽

Thematic Apperception ◽

And Gender ◽

The Given

Abstract. The Thematic Apperception Test is one of the most frequently administered apperceptive techniques. Formal scoring systems are helpful in evaluating story responses. TAT stories, made by 20 males and 20 females in the situation of legal divorce proceedings, were coded for detection and comparison of their personal problem solving ability. The evaluating instrument utilized was the Personal Problem Solving System-Revised (PPSS-R) as developed by G. F. Ronan. The results indicate that in relation to card 1, men more often than women saw the cause of the problem as removable. With card 6GF, women were more motivated to resolve the given problem than were men, women had a higher personal control and their stories contained more optimism compared to men’s stories. In relation to card 6BM women, more often than men, used emotions generated from the problem to orient themselves within the problem. With card 13MF, the men’s level of stress was less compared to that of the women, and men were more able to plan within the context of problem-solving. Significant differences in the examined groups were found in those cards which depicted significant gender and parental potentials. The TAT can be used to help identify personality characteristics and gender differences.

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Lung Ultrasound Findings in a Covid-19 Patient with Negative Chest CT

Ultraschall in der Medizin - European Journal of Ultrasound ◽

10.1055/a-1248-9068 ◽

2020 ◽

Author(s):

Yale Tung Chen ◽

Milagros Martí de Gracia ◽

Maria Luz Parra Gordo ◽

Silvia Ossaba Velez ◽

Sergio Agudo-Fernández

Keyword(s):

Lung Ultrasound ◽

Chest Ct ◽

Ultrasound Findings

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Myelodysplastisches Syndrom (MDS): Neue Erkenntnisse zu Diagnostik und Risikostratifizierung

Onkologische Welt ◽

10.1055/s-0038-1630262 ◽

2012 ◽

Vol 03 (06) ◽

pp. 253-253

Author(s):

Günter Springer

Keyword(s):

Scoring Systems ◽

Molekulare Marker ◽

Myelodysplastisches Syndrom

Es zeichnet sich ab, dass molekulare Marker zukünftig Diagnose, Risikostratifizierung und Therapieentscheidung beim MDS beeinflussen werden. Mit der revidierten Form des Internationalen Prognostischen Scoring Systems (IPSS) lässt sich der MDS-Verlauf präziser voraussagen als mit dem bisherigen Goldstandard.

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