Molecular determination of progesterone receptor’s PROGINS allele (Alu insertion) and its association with the predisposition and susceptibility to polycystic ovary syndrome (PCOS)

2022 ◽  
Author(s):  
Rashid Mir ◽  
Malik A. Altayar ◽  
Abdullah Hamadi ◽  
Faris J. Tayeb ◽  
Nizar H. Saeedi ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Alu Insertion ◽  
Molecular Determination

scholarly journals Determination of the source of androgen excess in functionally atypical polycystic ovary syndrome by a short dexamethasone androgen-suppression test and a low-dose ACTH test

2011 ◽  
Vol 26 (11) ◽  
pp. 3138-3146 ◽  
Author(s):  
Robert L. Rosenfield ◽  
Monica Mortensen ◽  
Kristen Wroblewski ◽  
Elizabeth Littlejohn ◽  
David A. Ehrmann
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Low Dose ◽  
Polycystic Ovary ◽  
Acth Test ◽  
Androgen Excess ◽  
Ovary Syndrome ◽  
Suppression Test ◽  
Androgen Suppression

scholarly journals Determination of Ovarian Reserve with Anti-Mullerian Hormone in Patients with Polycystic Ovary Syndrome and Premenopausal Women

2014 ◽  
Vol 4 (2) ◽  
pp. 62-68
Author(s):  
Cihan Inan ◽  
Nese Yucel ◽  
Banu Isbilen ◽  
Kemal Ferruh Isman ◽  
Ergun Bilgic ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Ovarian Reserve ◽  
Polycystic Ovary ◽  
Premenopausal Women ◽  
Ovary Syndrome

scholarly journals Determination of Serum Adiponectin Levels in Normal Weight Women with Polycystic Ovary Syndrome

2015 ◽  
Vol 57 (2) ◽  
pp. 175-178
Author(s):  
Rana A. Hamdi ◽  
◽  
Nawar S. Mohammed ◽  
Afraa M. AL-Naddawi ◽  
◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Normal Weight ◽  
Serum Adiponectin ◽  
Ovary Syndrome

Impact of Autoimmune Thyroiditis on Reproductive and Metabolic Parameters in Patients with Polycystic Ovary Syndrome

2018 ◽  
Vol 126 (04) ◽  
pp. 198-204 ◽  
Author(s):  
Jan Ulrich ◽  
Julia Goerges ◽  
Christoph Keck ◽  
Dirk Müller-Wieland ◽  
Sven Diederich ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Autoimmune Thyroiditis ◽  
Polycystic Ovary ◽  
Metabolic Parameters ◽  
Ovary Syndrome ◽  
Free Androgen Index ◽  
Patient Groups ◽  
Using Data ◽  
The Impact

Abstract Background Autoimmune thyroiditis (AIT) has been found to be associated with polycystic ovary syndrome (PCOS). The aim of this retrospective cohort study using data from a fertility clinic, with patients recruited from 2009 to 2010, was to confirm the higher prevalence of AIT in PCOS and to evaluate the impact of AIT on reproductive and metabolic parameters of PCOS patients. Methods Patients comprised 827 PCOS subjects seen for reproductive or metabolic complaints. Patients presenting primarily for thyroid problems were excluded. All patients were tested for the presence of AIT by laboratory testing and thyroid ultrasound. The impact of AIT on PCOS was evaluated by determination of reproductive and metabolic parameters. Results Patients with PCOS and AIT as compared to those only with PCOS, had a lower prevalence of elevated testosterone (45 vs. 61%; p=0,0001), free androgen index (5,96±5,41 vs. 7,02±7,6; p<0,001) and hyperandrogenemia (66 vs. 78%; p<0,001). Also testosterone levels were lower in PCOS patients with AIT (0,50±0,30 vs. 0,63±0,71; p=0,0006). Consequently, in these patients, hirsutism was less frequent (51 vs. 66%; p=0,0021). There was no difference in the prevalence of acne, alopecia, a-/ or oligomenorrhea or PCO-morphology in the two patient groups. Patients with PCOS and AIT were more obese by 2 kg/m² BMI on average. A higher BMI correlated with a higher TSH value, although all patients were euthyroid. Conclusions AIT is more prevalent in PCOS than in controls. PCOS patients with AIT have less severe hyperandrogenemia and hyperandrogenism but are likely to suffer from an elevated metabolic risk.

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