Prevalence of insulin resistance and determination of risk factors for glucose intolerance in polycystic ovary syndrome: a cross-sectional study of Chinese infertility patients

2009 ◽  
Vol 91 (5) ◽  
pp. 1864-1868 ◽  
Author(s):  
Hsiao-Jui Wei ◽  
Robert Young ◽  
I-Li Kuo ◽  
Chian-Mey Liaw ◽  
Han-Sun Chiang ◽  
...  
2016 ◽  
Vol 4 (4) ◽  
pp. 607-612
Author(s):  
Sasha Jovanovska-Mishevska ◽  
Aleksandra Atanasova-Boshku ◽  
Iskra Bitoska ◽  
Irfan Ahmeti ◽  
Biljana Todorova ◽  
...  

BACKGROUND: Polycystic ovary syndrome (PCOS) is complex hormonal, metabolic and reproductive disorder and is a leading cause of female infertility. Hyperinsulinemia secondary to insulin resistance plays important role in the pathogenesis of PCOS.AIM: To assess the sensitivity of different indices of insulin resistance and their relevance in a clinical setting.MATERIAL AND METHODS: A cross-sectional study of 43 patients with PCOS and 29 noromo ovulatory women as a control group was conducted. Standard clinical, anthropometrical and hormonal testing for hyperandrogenism was conducted, as well as oral glucose tolerance test with determination of basal and stimulated glucose and insulin values.RESULTS: The dynamic I/G index showed the highest sensitivity and specificity, but the static indexes HOMA-IR and QUICKI, although based on only basal glycemic and insulinemic values, showed good sensitivity, 90.38% and 94.01% respectively. HOMA-IR showed significant positive correlation with the stimulated insulin values.CONCLUSIONS: Our results support the use of static indexes in the evaluation of insulin resistance in women with PCOS in a clinical setting, offering a simple assessment of insulin resistance in PCOS, which holds great prognostic and treatment implications.


2010 ◽  
Vol 8 (1) ◽  
pp. 151 ◽  
Author(s):  
Dimitrios Panidis ◽  
Konstantinos Tziomalos ◽  
Ekaterini Koiou ◽  
Eleni A Kandaraki ◽  
Elena Tsourdi ◽  
...  

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