Effect of a magnetic field on the rheological properties of iron oxide–water–glycerol system

2016 ◽  
Vol 55 (2) ◽  
pp. 155-161 ◽  
Author(s):  
Sergey A. Vshivkov ◽  
Elena V. Rusinova ◽  
Andrei G. Galyas
2019 ◽  
Vol 16 (1) ◽  
pp. 119-140
Author(s):  
S.E. E. Hamza

The study of magnetic suspensions (MS) and magnetic field effects on their rheological properties is of evident practical importance due to its ability to orient and change their physical properties, especially their viscosity, by magnetic fields. This research presents the effect of a uniform magnetic field on the flow of MS in the annular region between two concentric cylinders. The motion of the fluid is due to the rotation of the inner cylinder with a constant angular velocity. An exact solution of the governing equations is obtained in the form of modified Bessel functions of the first and second kinds. The torque, which must be applied to the inner cylinder in order to maintain the rotation, is also calculated. The results show that as the magnetic parameter increases, the velocity profile decreases, while the torque increases due to the effect of magnetic force against the flow direction. In order to model the magnetoviscous effects, experiments were performed for different shear rates and different magnetic field strengths by using specially designed rheometers. The studied samples are iron oxide-water-glycerol system,  ferrofluid nanoparticles, MAG DX biocompatible ferrofluid. The theoretical analysis is based on Giesekus model for MS. This model gives more accurate results and takes into account the effects of viscoelastic shear thinning characteristics. It is found that a magnetic field increases the viscosity of all suspensions under consideration. Finally, new proposed correlation for the viscosity of MS as a function of both shear rate and magnetic field has been suggested.


Magnetorheological fluid is an admirable class of smart material. This fluid responses and adapts itself to the external magnetic field applied and hence, its rheological properties vary with respect to the field intensity. In this research work, Iron oxide nanoparticles are synthesized by co–precipitation method with ammonia as base reagent. Basic surface and size and magnetic field morphologies of the prepared particles are studied. Synthesized iron particles are used to prepare magnetorheological fluid. The rheological properties of the prepared fluid are studied to know about its viscosity and shearing stress-strain behavior.


2017 ◽  
Vol 6 (5) ◽  
pp. 449-472 ◽  
Author(s):  
Marina Fontes de Paula Aguiar ◽  
Javier Bustamante Mamani ◽  
Taylla Klei Felix ◽  
Rafael Ferreira dos Reis ◽  
Helio Rodrigues da Silva ◽  
...  

AbstractThe purpose of this study was to review the use of the magnetic targeting technique, characterized by magnetic driving compounds based on superparamagnetic iron oxide nanoparticles (SPIONs), as drug delivery for a specific brain locus in gliomas. We reviewed a process mediated by the application of an external static magnetic field for targeting SPIONs in gliomas. A search of PubMed, Cochrane Library, Scopus, and Web of Science databases identified 228 studies, 23 of which were selected based on inclusion criteria and predetermined exclusion criteria. The articles were analyzed by physicochemical characteristics of SPIONs used, cell types used for tumor induction, characteristics of experimental glioma models, magnetic targeting technical parameters, and analysis method of process efficiency. The study shows the highlights and importance of magnetic targeting to optimize the magnetic targeting process as a therapeutic strategy for gliomas. Regardless of the intensity of the patterned magnetic field, the time of application of the field, and nanoparticle used (commercial or synthesized), all studies showed a vast advantage in the use of magnetic targeting, either alone or in combination with other techniques, for optimized glioma therapy. Therefore, this review elucidates the preclinical and therapeutic applications of magnetic targeting in glioma, an innovative nanobiotechnological method.


2017 ◽  
Vol 16 (2) ◽  
pp. 145-148
Author(s):  
Sergey Kolesov ◽  
Andrey Panteleyev ◽  
Maxim Sazhnev ◽  
Arkadiy Kazmin

ABSTRACT Objective: To determine the amount of loss of function after spinal cord transection of varying extents, and whether magnetic iron oxide nanoparticles, in combination with an external magnetic field, improve the rate of subsequent functional recovery in rats. Methods: The animals were divided into groups with 50%, 80% and complete spinal cord transection. The animals of all three study groups were administered magnetic iron oxide nanoparticle suspension to the area of injury. The three control groups were not administered magnetic nanoparticles, but had corresponding transection levels. All animals were exposed to a magnetic field for 4 weeks. Loss of postoperative function and subsequent recovery were assessed using the BBB motor function scale and somatosensory evoked potential monitoring on the first day after surgery, and then weekly. Terminal histological analysis was also conducted in all the groups. Results: The animals in the control or complete transection groups did not demonstrate statistically significant improvement in either the BBB scores or evoked potential amplitude over the four-week period. In the group with 50% transection, however, a statistically significant increase in evoked potential amplitude and BBB scores was observed four weeks after surgery, with the highest increase during the second week of the study. In the group with 80% transection, only improvement in evoked potential amplitude was statistically significant, although less pronounced than in the 50% transection group. Conclusion: The use of magnetic iron oxide nanoparticles in combination with a magnetic field leads to higher rates of functional recovery after spinal cord injury in laboratory animals. The mechanism of this functional improvement needs further investigation.


1970 ◽  
Vol 12 (4) ◽  
Author(s):  
Md. Shariful Islam, Yoshihumi Kusumoto, Md. Abdulla Al-Mamun And Yuji Horie

We synthesized mixed α and γ-Fe2O3 nanoparticles and investigated their toxic effects against HeLa cells under induced AC (alternating current) magnetic-fields and photoexcited conditions at room temperature. The findings revealed that the cell-killing percentage was increased with increasing dose for all types of treatments. Finally, 99% cancer cells were destructed at 1.2 mL dose when exposed to combined AC magnetic-field and photoexcited conditions (T3) whereas 89 and 83 % of HeLa cells were killed under only AC magnetic-field induced (T1) or only photoexcited (T2) condition at the same dose.ABSTRAK: Campuran α dan zarah γ-Fe2O3 bersaiz nano disintesiskan dan kesan toksidnya terhadap sel HeLa dikaji dibawah aruhan medan magnet arus ulang-alik (alternating current (AC)) dan keadaan photoexcited (proses ransangan atom atau molekul suatu bahan dengan penyerapan tenaga sinaran) pada suhu bilik. Penemuan mendedahkan bahawa peratusan sel yang musnah bertambah dengan pertambahan dos untuk semua jenis rawatan. Akhirnya, 99% sel kanser dimusnahkan pada kadar dos 1.2mL setelah didedahkan terhadap kombinasi medan magnet AC dan keadaan photoexcited (T3) dimana 89% dan 83% sel HeLa dimusnahkan dengan hanya di bawah aruhan medan magnet AC (T1) atau hanya pada keadaan photoexcited (T2) pada kadar dos yang sama.KEY WORDS : Cancer, Hyperthermia, Iron oxide nanoparticles, Heat dissipation,    Cytotoxicity, HeLa cell.


2008 ◽  
Vol 23 (12) ◽  
pp. 3415-3424 ◽  
Author(s):  
Koichiro Hayashi ◽  
Toshifumi Shimizu ◽  
Hidefumi Asano ◽  
Wataru Sakamoto ◽  
Toshinobu Yogo

Size-controlled spinel iron oxide (SIO) nanoparticle/organic hybrid was synthesized in situ from iron (III) allylacetylacetonate (IAA) at around 80 °C. The formation of SIO particles chemically bound with organics was confirmed by infrared and x-ray photoelectron spectroscopy. The sizes of SIO nanoparticles in the hybrids were monodispersed and ranged from 7 to 23 nm under controlled hydrolysis conditions. The hybrid including SIO particles of 7.3 nm was superparamagnetic, whereas those dispersed with particles above 11 nm were ferrimagnetic. The specific absorption rate (SAR) value was dependent upon the magnetic properties of the hybrid at 100 Oe. The SAR was 15.2 W g−1 in a 230 kHz alternating magnetic field and 100 Oe when the crystallite size of SIO particle in the hybrid was 16 nm. The temperatures of agars dispersed with hybrid powders of 5 and 8 mg ml−1 reached the optimum temperature (42 °C) for 17 and 8 min, respectively. The increase in temperature was controlled in terms of the strength of magnetic field. The simulation of heat transfer in the agar phantom model revealed that the suitable temperature distribution for therapy was attained from 15 to 20 min at 230 kHz and 100 Oe.


2018 ◽  
Vol 14 (5) ◽  
pp. 1643-1654 ◽  
Author(s):  
Mookkandi Palsamy Kesavan ◽  
Niranjan G. Kotla ◽  
Srinivasan Ayyanaar ◽  
Gujuluva Gangatharan Vinoth Kumar ◽  
Gurusamy Rajagopal ◽  
...  

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