scholarly journals Comparison of protective effect of ascorbic acid on redox and endocannabinoid systems interactions in in vitro cultured human skin fibroblasts exposed to UV radiation and hydrogen peroxide

2017 ◽  
Vol 309 (4) ◽  
pp. 285-303 ◽  
Author(s):  
Agnieszka Gęgotek ◽  
Katarzyna Bielawska ◽  
Michał Biernacki ◽  
Ilona Zaręba ◽  
Arkadiusz Surażyński ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Ascorbic Acid ◽  
Protective Effect ◽  
Human Skin ◽  
Uv Radiation ◽  
Skin Fibroblasts ◽  
Human Skin Fibroblasts

The Effect of Practolol, In Vitro Generated Metabolites of Practolol and Chemical Analogues on the Rate of Growth of Human Skin Fibroblasts

1984 ◽  
Vol 12 (2) ◽  
pp. 89-97
Author(s):  
Graham R. Elliott ◽  
H.E. Amos ◽  
James W. Bridges
Keyword(s):  
Human Skin ◽  
Psoriasis Patient ◽  
Skin Fibroblasts ◽  
Human Skin Fibroblasts ◽  
Cell Type ◽  
Normal Human Skin ◽  
Rate Of Growth ◽  
Structural Analogues ◽  
Normal Human

The rate of growth of normal human skin fibroblasts was inhibited in a dose related, reversible, fashion by practolol (N-4-(2-hydroxy)-3 (1-methyl)-aminopropoxyphenylacetamine) (ID50 1.35 ± 0.14 x 10-3M), propranolol (1-(isopropylamino)-3(1-naphthyl-oxy)-2-propranolol) (ID50 0.145 ± 0.02 x 10-3M) and paracetamol (N-(4-hydroxyphenyl) acetamide) (ID50 0.85 ± 0.2 x 10-3M). Skin fibroblasts isolated from a psoriasis patient were more sensitive towards practolol (ID50 0.48 ± 0.14 x 10-3M) and propranolol (ID50 0.032 ± 0.002 x 10-3M), but less sensitive towards paracetamol (ID50 1.3 ± 0.07 x 10-3M). In vitro generated metabolites of practolol, using normal or Arochlor 1254-pretreated hamster liver preparations, and structural analogues of practolol had no effect upon the growth of either cell type.

scholarly journals Anethole prevents hydrogen peroxide-induced apoptosis and collagen metabolism alterations in human skin fibroblasts

2014 ◽  
Vol 394 (1-2) ◽  
pp. 217-224 ◽  
Author(s):  
Anna Galicka ◽  
Rafał Krętowski ◽  
Jolanta Nazaruk ◽  
Marzanna Cechowska-Pasko
Keyword(s):  
Hydrogen Peroxide ◽  
Human Skin ◽  
Skin Fibroblasts ◽  
Collagen Metabolism ◽  
Human Skin Fibroblasts ◽  
Induced Apoptosis

The effects of ascorbic acid on collagen synthesis by cultured human skin fibroblasts

1991 ◽  
Vol 19 (1) ◽  
pp. 48S-48S ◽  
Author(s):  
SHONA M.L. ANDERSON ◽  
W.H. IRWIN McLEAN ◽  
ROBERT J. ELLIOTT
Keyword(s):  
Ascorbic Acid ◽  
Human Skin ◽  
Collagen Synthesis ◽  
Skin Fibroblasts ◽  
Human Skin Fibroblasts

scholarly journals Basal Level of Autophagy Is Increased in Aging Human Skin Fibroblasts In Vitro, but Not in Old Skin

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0126546 ◽  
Author(s):  
Dino Demirovic ◽  
Carine Nizard ◽  
Suresh I. S. Rattan
Keyword(s):  
Human Skin ◽  
Skin Fibroblasts ◽  
Human Skin Fibroblasts
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