Fertility-sparing surgery for patients with malignant ovarian germ cell tumors: 10 years of clinical experience from a tertiary referral center

2020 ◽  
Vol 301 (5) ◽  
pp. 1227-1233 ◽  
Author(s):  
Mislav Mikuš ◽  
Nikolina Benco ◽  
Luka Matak ◽  
Pavao Planinić ◽  
Mario Ćorić ◽  
...  
Keyword(s):  
Germ Cell ◽  
Clinical Experience ◽  
Germ Cell Tumors ◽  
Tertiary Referral ◽  
Tertiary Referral Center ◽  
Referral Center ◽  
Fertility Sparing Surgery ◽  
Fertility Sparing

Bilateral Testicular Germ Cell Tumors: A Case-Series From a UK-Based Tertiary Referral Center Over 19 Years

2018 ◽  
Vol 16 (3) ◽  
pp. e513-e516 ◽  
Author(s):  
Robert A. Watson ◽  
Robert D. Morgan ◽  
Johnson Joseph ◽  
Shivan Sivakumar ◽  
Clare Verrill ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumors ◽  
Case Series ◽  
Testicular Germ Cell Tumors ◽  
Tertiary Referral ◽  
Testicular Germ Cell ◽  
Tertiary Referral Center ◽  
Referral Center

Short-term outcome of fertility-sparing laparoscopic excision of deeply infiltrating pelvic endometriosis performed in a tertiary referral center

2010 ◽  
Vol 93 (1) ◽  
pp. 39-45 ◽  
Author(s):  
George K. Pandis ◽  
Ertan Saridogan ◽  
Alastair C.J. Windsor ◽  
Cagri Gulumser ◽  
C. Richard G. Cohen ◽  
...  
Keyword(s):  
Pelvic Endometriosis ◽  
Tertiary Referral ◽  
Short Term ◽  
Term Outcome ◽  
Tertiary Referral Center ◽  
Referral Center ◽  
Short Term Outcome ◽  
Fertility Sparing ◽  
Laparoscopic Excision

scholarly journals Fertility sparing surgery in malignant ovarian germ cell tumors (MOGCTs): 15 years experiences

2021 ◽  
Author(s):  
Shima Alizadeh ◽  
Narges Zamani ◽  
Mohadese Rezaei Poor ◽  
Sedigheh Ghasemian Dizajmehr ◽  
Mitra Modares Gilani
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumors ◽  
Fertility Sparing Surgery ◽  
Fertility Sparing

scholarly journals Treatment outcomes in malignant ovarian germ cell tumors

2017 ◽  
Vol 6 (12) ◽  
pp. 5256
Author(s):  
Ram Kumar B.
Keyword(s):  
Germ Cell ◽  
Chemotherapy Regimen ◽  
Primordial Germ Cells ◽  
Germ Cell Tumour ◽  
Germ Cell Tumors ◽  
Cystic Teratoma ◽  
Germ Cell Tumours ◽  
Fertility Sparing Surgery ◽  
Fertility Sparing ◽  
Yolk Sac Tumour

Background: Malignant ovarian germ cell tumours are rare group of ovarian neoplasms derived from primordial germ cells of the ovary. Objective of present study was to evaluate the outcome of treatment in malignant germ cell tumours.Methods: 21 Patients of malignant ovarian germ cell tumours registered at Department of Medical Oncology, Institute of Obstetrics and Gynaecology, Chennai for the period from January 2012 to December 2015 were retrospectively analyzed for treatment outcomes.Results: The median age at presentation was 21 years with age range between 14 and 40 years. 9patients (43%) presented with mixed germ cell tumour, 6 patients (29%) with dysgerminoma, 3 patients (14%) with yolk sac tumour and 3 patients (14%)with mature cystic teratoma. 13 patients (62%) presented with Stage I disease, 5 patients (24%) with Stage III and 3 patients (14%) with Stage II. Fertility sparing surgery was done in 15 patients (71%), and 4 patients (19%) who completed family had TAH with BSO done. Adjuvant Chemotherapy was given for 16 patients (76%) and as Neoadjuvant in 2patients (10%) who had biopsy alone performed. 4patients (19%) developed recurrence and was taken for salvage PVI chemotherapy.Conclusions: Malignant ovarian germ cell tumours are relatively uncommon neoplasms characterized by high chemo sensitivity. This study confirms that malignant ovarian germ cell tumours have excellent prognosis and the effectiveness of BEP chemotherapy regimen. Fertility sparing surgery is feasible in most cases. Advanced Stage configured as an important risk factor for survival. The chemotherapy regimen was associated with significant but manageable toxicity.

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