scholarly journals Can preoperative results predict the need for future reintervention following injection laryngoplasty for unilateral vocal fold paralysis?

2021 ◽  
Author(s):  
Beata Miaśkiewicz ◽  
Aleksandra Panasiewicz ◽  
Elżbieta Gos ◽  
Paulina Krasnodębska ◽  
Piotr H. Skarżyński ◽  
...  
Keyword(s):  
Relative Risk ◽  
Vocal Fold ◽  
Statistical Significance ◽  
Vocal Fold Paralysis ◽  
Control Group ◽  
Study Group ◽  
Injection Laryngoplasty ◽  
Unilateral Vocal Fold Paralysis ◽  
Voice Assessment ◽  
The Difference

Abstract Purpose The objective was to investigate whether a patient’s preoperative test results can predict the need for future reoperation in unilateral vocal fold paralysis (UVFP). Methods A single-centre retrospective study was performed. The study group consisted of 18 patients with UVFP who had been treated with injection laryngoplasty but who required further treatment and were augmentated again within 36 months. The control group consisted of 33 injected patients who had not required reintervention up to 36 months later. Results Only glottal gap was associated with a relative risk for reinjection. Glottal gap was found to be severe in 77.8% of the patients from the study group compared to 42.4% of the controls, and the difference was statistically significant. The kind of injected material (calcium hydroxylapatite or hyaluronic acid), age, and voice assessment (perceptual, objective, or subjective) did not seem to affect the likelihood of reoperation being needed. There were no between-group statistically significant differences in individual aspects of the GRBAS scale. The global score was slightly higher in the study group, but it did not reach statistical significance (U = 198.5; p = 0.09). A comparison of VHI scores did not yield statistically significant differences between the study and control groups. No significant differences in objective acoustic voice parameters were observed between the groups. Conclusion Only glottal gap occurred to be associated with a relative risk for reinjection. A kind of injected material (CaHA or HA), age, perceptual, objective and subjective voice assessment do not seem to impact the likelihood of reoperation in patients with UVFP.

Analysis of Nursing Cooperation in Microscopic Pituitary Tumor Resection via Transsphenoidal Approach

2021 ◽  
Vol 7 (6) ◽  
pp. 6445-6452
Author(s):  
Haijuan Hu ◽  
Yishu Zhao ◽  
Jianhua Ma
Keyword(s):  
Statistical Significance ◽  
Tumor Resection ◽  
Nursing Intervention ◽  
Transsphenoidal Approach ◽  
Control Group ◽  
Mechanical Equipment ◽  
Study Group ◽  
Observation Group ◽  
The Difference ◽  
Better Than

To analyze the clinical effect of nursing cooperation in transsphenoidal approach microscopic hypophysectomy. From January 2017 to January 2020, 80 patients who underwent transsphenoidal microscopic hypophysectomy in our hospital were selected to participate in the analysis and study. They were divided into two groups according to the randomized allocation, namely the observation group and the control group. Among them, 40 patients in the observation group and 40 patients in the control group were given routine nursing care for the patients in the control group, and comprehensive nursing intervention was adopted for the patients in the observation group, and the overall nursing effect of the two groups of patients was compared. After taking different nursing methods, the condition of patients in both groups was effectively controlled, and the effective rate of patients in the observation group with comprehensive nursing intervention was significantly better than that of patients in the control group with conventional nursing methods, and the difference had certain statistical significance (P < 0.05); The satisfaction degree of patients in the study group was significantly better than that of patients in the control group, and the difference was statistically significant (P < 0.05). The degree of negative emotions of patients in the study group was significantly better than that of patients in the control group after receiving comprehensive nursing intervention, and the difference was statistically significant (P < 0.05), and the difference in the incidence of adverse events between the two groups was not statistically significant (P > 0.05); The scores of each index of SF-36 questionnaire of patients in both groups were higher than those before nursing, and the scores of each index of patients in observation group were higher than those of patients in control group, and the difference was statistically significant (P > 0.05). With adequate preoperative preparation and mastery of the use of mechanical equipment, comprehensive nursing intervention can effectively improve the treatment effect of patients, make patients more satisfied with the nursing work, and can soothe patients’ negative psychological mood, eliminate panic, improve patients' life confidence, enhance intraoperative cooperation, and ensure that the operation can be completed smoothly.

scholarly journals Evaluation of Diffusional Characteristics and Microstructure in Unilateral Vocal Fold Paralysis Using Diffusion Tensor Imaging

2019 ◽  
pp. 014556131987472
Author(s):  
Jie Cai ◽  
Logan Klein ◽  
Pinhong Wu ◽  
Azure Wilson ◽  
Xinlin Xu ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Diffusion Tensor ◽  
Vocal Fold Paralysis ◽  
Cross Sectional Area ◽  
Control Group ◽  
Sectional Area ◽  
Unilateral Vocal Fold Paralysis ◽  
Cross Sectional ◽  
Injury Group ◽  
The Cross

Objective: To investigate the value of diffusion tensor imaging (DTI) in the evaluation of vocal fold tissue microstructure after recurrent laryngeal nerve (RLN) injury. Methods: Six canines were divided into 2 groups: a unilateral vocal fold paralysis group (n = 4) and a control group (n = 2). The RLN was cut in the unilateral vocal fold paralysis group, and no intervention was applied in the control group. After 4 months, the canines’ larynges were removed and placed in a small animal magnetic resonance imaging (MRI) system (9.4T BioSpec MRI; Bruker, Germany). After scanning, the vocal folds were isolated, sectioned, and stained. The slides were then analyzed for the cross-sectional area and muscle fiber density through feature extraction technology. Pearson correlation analysis was performed on the DTI scan and histological section extraction results. Results: In the vocal fold muscle layer, the fractional anisotropy (FA) of the unilateral RLN injury group was higher than that of the control group, and the Tensor Trace was lower than that of the control group. This difference was statistically significant, P < .05. In the lamina propria, the FA of the unilateral RLN injury group was lower than that of the control group, P > .05, and the Tensor Trace was lower than that of the control group, P < .05. The muscle fiber cross-sectional area of the RLN injury group was significantly smaller than the control group with statistical significance, P < .05, and the density of muscle fibers was lower, P < .05. The correlation coefficient between FA and the cross-sectional area was −0.838, P = .002, and .726; P = .017 between Tensor Trace and the cross-sectional area. Conclusion: Diffusion tensor imaging is an effective method to assess the changes in the microstructure of atrophic vocal fold muscle tissue after RLN injury.

The Efficacy of Injection Laryngoplasty in Managing Unilateral Vocal Fold Paralysis

2004 ◽  
Vol 131 (2) ◽  
pp. P213-P213
Author(s):  
Siew Shuen Chao ◽  
Scott M Graham ◽  
Lucy Karnell ◽  
Alexander PM Jay ◽  
Henry T Hoffman
Keyword(s):  
Vocal Fold ◽  
Vocal Fold Paralysis ◽  
Injection Laryngoplasty ◽  
Unilateral Vocal Fold Paralysis

Cardiothoracic Patients with Unilateral Vocal Fold Paralysis: Pneumonia Rates Following Injection Laryngoplasty

2020 ◽  
Vol 129 (11) ◽  
pp. 1129-1134 ◽  
Author(s):  
Jason H. Barnes ◽  
Diana M. Orbelo ◽  
Michael F. Armstrong ◽  
Semirra L. Bayan ◽  
Christine M. Lohse ◽  
...  
Keyword(s):  
Aspiration Pneumonia ◽  
Vocal Fold ◽  
Proportional Hazards ◽  
Retrospective Chart Review ◽  
Vocal Fold Paralysis ◽  
Cox Proportional Hazards ◽  
Cardiothoracic Surgery ◽  
Injection Laryngoplasty ◽  
Unilateral Vocal Fold Paralysis ◽  
Level Of Evidence

Objective: Recurrent laryngeal nerve injury is a potential complication of cardiothoracic surgery and cause of unilateral vocal fold paralysis (UVFP). Injection laryngoplasty (IL) is an intervention offered to patients with UVFP to alleviate symptoms including dysphagia, dysphonia and weak cough. There is no definitive evidence that IL prevents pneumonia. In this study, we compare rates of pneumonia in patients with UVFP secondary to cardiothoracic surgery who did or did not undergo IL. Methods: A retrospective chart review identified patients diagnosed with UVFP by an otolaryngologist using flexible laryngoscopy following cardiothoracic surgery from January 1, 2008 to December 31, 2017. Each subject was grouped by IL status and assessed for subsequent pneumonia within 6 months of their diagnosis of UVFP. The association of IL with pneumonia was evaluated using Cox proportional hazards regression. Results: Of 92 patients who met inclusion criteria, 35 (38%) underwent IL and 57 (62%) did not. Twenty patients developed pneumonia, four who had undergone IL and 16 who had not; 12 patients developed aspiration pneumonia including two having undergone IL and 10 who had not. Those who had IL were less likely to develop total pneumonia compared to those who had not (HR = 0.33, P = .045). The protective effect of IL was not as clearly sustained when measuring for aspiration pneumonia, specifically (HR = 0.34; P = .10). Discussion: Injection laryngoplasty may reduce the risk of pneumonia in patients with UVFP secondary to cardiothoracic surgery; however, further research is needed to quantify the potential protective nature of IL in this patient population. Level of evidence: 3 (A retrospective cohort study).

scholarly journals Injection laryngoplasty as miniinvasive office-based surgery in patients with unilateral vocal fold paralysis – voice quality outcomes

2017 ◽  
Vol 3 ◽  
pp. 277-284 ◽  
Author(s):  
Ewelina M. Sielska-Badurek ◽  
Maria Sobol ◽  
Katarzyna Jędra ◽  
Anna Rzepakowska ◽  
Ewa Osuch-Wójcikiewicz ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Voice Quality ◽  
Vocal Fold Paralysis ◽  
Injection Laryngoplasty ◽  
Unilateral Vocal Fold Paralysis ◽  
Quality Outcomes

Adiponectin and leptin levels in normal weight women with polycystic ovary syndrome

2020 ◽  
Vol 41 (4) ◽  
Author(s):  
Murat Gözüküçük ◽  
Aslı Yarcı Gürsoy ◽  
Emre Destegül ◽  
Salih Taşkın ◽  
Hakan Şatıroğlu
Keyword(s):  
Insulin Resistance ◽  
Polycystic Ovary ◽  
Statistical Significance ◽  
Free Testosterone ◽  
Normal Weight ◽  
Control Group ◽  
Study Group ◽  
Model Assessment ◽  
Homeostatic Model Assessment ◽  
The Difference

Abstract Objectives Since polycystic ovarian syndrome (PCOS) is prevalent in reproductive women with obesity and insulin resistance, adipocytokines are often accused and investigated for pathophysiology. The aim of this study was to evaluate the adiponectin and leptin levels in normal-weight women with PCOS. Methods Forty women with PCOS and 40 age and body mass index (BMI) matched controls were included in the study. Adiponectin and leptin levels in addition to other biochemical parameters were measured. Results Leptin levels were statistically significantly higher in the study group compared to the control group (6.53 ± 2.670 vs 3.37 ± 2.002 ng/mL, p < 0.001 respectively). Although Adiponectin levels were lower in the study group compared to the control group (28.89 ± 16.124 μg/mL vs 31.05 ± 20.507, p = 0.714 respectively) the difference did not reach statistical significance. Leptin levels were positively correlated with fasting glucose, fasting insulin, free testosterone levels and homeostatic model assessment of insulin resistance (HOMA-IR) values. Adiponectin levels were negatively correlated with BMI. Conclusions Adiponectin and leptin have been suggested to play a crucial role in the pathogenesis of PCOS. Different adipocytokine levels in the normal weight PCOS group compared to age and BMI matched controls support the idea that adipose tissue in this group of women has some distinctive features not only in high BMI subgroup but also in normal weight subgroup.

Role of Temporary Injection Laryngoplasty in Acute Unilateral Vocal Fold Paralysis with Aspiration

2009 ◽  
Vol 52 (3) ◽  
pp. 237 ◽  
Author(s):  
Hyun Chang ◽  
Youngjin Ahn ◽  
Yune Sung Lim ◽  
J. Hun Hah ◽  
Myung-Whun Sung ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Vocal Fold Paralysis ◽  
Injection Laryngoplasty ◽  
Unilateral Vocal Fold Paralysis
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