Predicting gene phenotype by multi-label multi-class model based on essential functional features

Author(s):  
Lei Chen ◽  
Zhandong Li ◽  
Tao Zeng ◽  
Yu-Hang Zhang ◽  
Hao Li ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-20 ◽  
Author(s):  
Mirosław Targosz ◽  
Wojciech Skarka ◽  
Piotr Przystałka

The article presents a method for optimizing driving strategies aimed at minimizing energy consumption while driving. The method was developed for the needs of an electric powered racing vehicle built for the purposes of the Shell Eco-marathon (SEM), the most famous and largest race of energy efficient vehicles. Model-based optimization was used to determine the driving strategy. The numerical model was elaborated in Simulink environment, which includes both the electric vehicle model and the environment, i.e., the race track as well as the vehicle environment and the atmospheric conditions. The vehicle model itself includes vehicle dynamic model, numerical model describing issues concerning resistance of rolling tire, resistance of the propulsion system, aerodynamic phenomena, model of the electric motor, and control system. For the purpose of identifying design and functional features of individual subassemblies and components, numerical and stand tests were carried out. The model itself was tested on the research tracks to tune the model and determine the calculation parameters. The evolutionary algorithms, which are available in the MATLAB Global Optimization Toolbox, were used for optimization. In the race conditions, the model was verified during SEM races in Rotterdam where the race vehicle scored the result consistent with the results of simulation calculations. In the following years, the experience gathered by the team gave us the vice Championship in the SEM 2016 in London.


Author(s):  
Ioulia Papageorgiou

Quantitative Archaeology had a rapid development in the past few decades due to the parallel development of methodologies in Physics, Chemistry and Geology that can be implemented in archaeological findings and produce measurements on a number of variables. Those measurements form the data, the basis for a statistical analysis, which in turn can provide us with objective results and answers, within the prediction or estimation framework, about the archaeological findings. Exploratory statistical analysis was almost exclusively used initially for analyzing such data mainly because of their simplicity. The simplicity originates from the fact that exploratory techniques do not rely on any distribution assumption and conduct a non-parametric statistical analysis. However the recent development of the statistical methodology and the computing software allows us to make use of more sophisticated statistical techniques and obtain more informative results. We explore and present applications of three such techniques. The finite mixture approach for model based clustering, the latent class model and the Bayesian mixture of normal distributions with unknown number of components. All three methods can be used for identifying sub-groups in the sample and classify the items.


2014 ◽  
Vol 989-994 ◽  
pp. 2037-2042
Author(s):  
Li Min Niu ◽  
Hao Guo ◽  
Jun Jie Chen

In order to analyze the gap of function network between Major depressive disorder and health person, this paper studies with modeling approach. This paper analyzes the function network of Major depressive disorder with the model based on anatomical distance and the number of common neighbor. The result shows that the distribution of the optimal brain function network is linear in all volunteer. And the slope of the linear relationship in the patients is less than health, so we hope this point can be as secondary evidence to determine the person whether fall ill. And we also propose two models and those models of brain function are based on anatomical distance or the number of common neighbor. Create the evaluation criteria for select the optimal brain function model network in each class model based on select the maximum value in the proportion of the common edges of two network accounted all edges. Select the model that can simulate the real brain function network by comparison with real data fMRI network. Finally, the results show the best model only is based on anatomical distance .


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